Protein

MCA_04619_1

Length
692 amino acids

Gene name: NOP2

Description: 25S rRNA (cytosine(2870)-C(5))-methyltransferase

Browser: contigC:3525177-3527256-

RNA-seq: read pairs 2341, FPKM 41.7, percentile rank 61.3% (100% = highest expression)

Protein function

Annotation:NOP225S rRNA (cytosine(2870)-C(5))-methyltransferase
KEGG:K14835NOP2 25S rRNA (cytosine2870-C5)-methyltransferase [EC:2.1.1.310]
EGGNOG:0PHXVNOP2S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein
SGD closest match:S000005005NOP225S rRNA (cytosine(2870)-C(5))-methyltransferase
CGD closest match:CAL0000190202CAALFM_CR04170WArRNA (Cytosine-C5-)-methyltransferase

Protein alignments

%idAln lengthE-value
MIA_01937_183.36%5290.0MIA_01937_1
A0A0J9X2K7_GEOCN73.37%5220.0Similar to Saccharomyces cerevisiae YNL061W NOP2 Probable RNA m(5)C methyltransferase OS=Geotrichum candidum GN=BN980_GECA01s03079g PE=3 SV=1
Q6CF36_YARLI69.69%5410.0YALI0B10560p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10560g PE=3 SV=1
UniRef50_G0W9F768.00%5500.0Uncharacterized protein n=64 Tax=Eukaryota TaxID=2759 RepID=G0W9F7_NAUDC
A0A167E8P3_9ASCO78.18%4400.0Ncl1p OS=Sugiyamaella lignohabitans GN=NCL1 PE=3 SV=1
A0A1D8PSN8_CANAL78.05%4420.0rRNA (Cytosine-C5-)-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR04170WA PE=3 SV=1
A0A1E3PMD8_9ASCO68.89%4790.0Putative RNA m(5)C methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23656 PE=3 SV=1
NOP2_YEAST76.36%4400.025S rRNA (cytosine(2870)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP2 PE=1 SV=1
A0A060T860_BLAAD68.70%5240.0ARAD1C33880p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33880g PE=3 SV=1
A0A1E4TAK6_9ASCO65.15%4390.0Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13118 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1256

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 692

Detailed signature matches

  1. Family IPR023267
    RNA (C5-cytosine) methyltransferase
    1. PR02008 (RCMTFAMILY)
  2. Family IPR023273
    RNA (C5-cytosine) methyltransferase, NOP2
    1. PR02012 (RCMTNOP2)
  3. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  4. Domain IPR031341
    Ribosomal RNA small subunit methyltransferase F, N-terminal
    1. PF17125 (Methyltr_R...)
  5. Domain IPR001678
    SAM-dependent methyltransferase RsmB/NOP2-type
    1. PF01189 (Methyltr_R...)
    2. PS51686 (SAM_MT_RSM...)
  6. Domain IPR011023
    Nop2p
    1. TIGR00446
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.70...
  3. G3DSA:3.40.50...
  4. mobidb-lite (disord...)

Protein sequence

>MCA_04619_1
MGRKAKNKQGVPPTLDEFLQDKEGTKKPTKQFSKKNSKRDSLTSKDKSDKKNKKEPKSKNSEEKSSKSSNKKNSKKSQDN
EEEEEDLESSRKSLFDNEDDNEVELEKDEFDDMEEESGDDVYDSEEEERARPKPMFSDDEDDEDPSTLEALNQQAIDQAL
AMDSDEPDSEDEIFASSEDEEGEGEDEEDEEERAKNPRAKILPDVVEGGIDEAPQDLAMIRTRILEIVKVLEDFKNLAEE
GRSRAEYVDQLIHDIATYYGYTRFLAEKLFNLFSPSEAIDFFEANEVARPVTIRTNTLKTRRRDLAQALVNRGVNLQPIP
GKWTKVGLQVFDSQVPIGATPEYLAGHYILQAASSFLPVMALDPQENERILDMAAAPGGKTTYISALMKNTGCVFANDFN
KERTKSLIANIHRLGCTNTIVCNYDAREFPRVIGGFNRVLLDAPCSGTGVIGKDPQVKTSRTELDFIQLPYLQKQLLLSA
IDSVDANVPEGQAVIVYSTCSVTVDENESVVDYALRKRPNVKLVDTGLQIGKPGFTSYRGKTFHPSVSLTRRYYPHTYNV
DGFYVAKFVKTAPSPHDKSKAGAKEKEDAARAEAEEEGISIINNDFAKFDDKEDEKYIDQARRTRLKRKGVDPRADPKKA
KKTKEDEDNETEGKKEKKKEKVSEEKKKEKTSEEKKKEKTSEEKKKKKKSEK

GO term prediction

Biological Process

GO:0006364 rRNA processing

Molecular Function

GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity

Cellular Component

None predicted.