Protein

MCA_04558_1

Length
1,980 amino acids


Gene name: DNF1B

Description: Phospholipid-transporting ATPase DNF1; Aminophospholipid translocase (flippase)

Browser: contigC:3369169-3375204+

RNA-seq: read pairs 5475, FPKM 34.1, percentile rank 56.3% (100% = highest expression)

Protein function

Annotation:DNF1BPhospholipid-transporting ATPase DNF1; Aminophospholipid translocase (flippase)
KEGG:K01530E3.6.3.1 phospholipid-translocating ATPase [EC:3.6.3.1]
EGGNOG:0PG3HPGUG_05698Phospholipid-translocating P-type ATPase domain-containing protein
SGD closest match:S000000968DNF1Phospholipid-transporting ATPase DNF1
CGD closest match:CAL0000173967orf19.932Phospholipid-transporting ATPase

Protein alignments

%idAln lengthE-value
MIA_00967_171.65%15310.0MIA_00967_1
A0A0J9X7B3_GEOCN60.86%17040.0Phospholipid-transporting ATPase OS=Geotrichum candidum GN=BN980_GECA04s03486g PE=3 SV=1
UniRef50_A0A0J9X7B360.86%17040.0Phospholipid-transporting ATPase n=2 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9X7B3_GEOCN
A0A060SZE9_BLAAD61.59%15310.0Phospholipid-transporting ATPase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07084g PE=3 SV=1
A0A1E3PGA2_9ASCO61.68%14250.0Phospholipid-transporting ATPase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83856 PE=3 SV=1
A0A161HKW8_9ASCO61.60%13540.0Phospholipid-transporting ATPase OS=Sugiyamaella lignohabitans GN=DNF1 PE=3 SV=1
Q6CDH4_YARLI59.44%13830.0Phospholipid-transporting ATPase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C00495g PE=3 SV=1
ATC5_YEAST58.59%13860.0Phospholipid-transporting ATPase DNF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DNF1 PE=1 SV=2
A0A1E4TDZ8_9ASCO56.27%13150.0Phospholipid-transporting ATPase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26222 PE=3 SV=1
A0A1D8PMY6_CANAL52.84%14460.0Phospholipid-transporting ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.932 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0411

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 1980

Detailed signature matches

    1. SSF81665 (Calcium A...)
    1. PF16209 (PhoLip_ATP...)
    1. SSF81653 (Calcium A...)
    1. SSF56784 (HAD-like)
    1. SSF81660 (Metal cat...)
    1. PF16212 (PhoLip_ATP...)
    1. PS00154 (ATPASE_E1_E2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF13246 (Cation_ATPase)
  2. PR00119 (CATATPASE)
  3. SFLDF00027 (p-type_...)
  4. SFLDG00002 (C1.7:_P...)
  5. TRANSMEMBRANE (Tran...)
  6. cd02073 (P-type_ATP...)
  7. mobidb-lite (disord...)

Residue annotation

  1. phosphorylation si...
  2. P-type ATPase sign...
  3. putative ATP bindi...
  4. SFLDG00002
  5. SFLDF00027

Protein sequence

>MCA_04558_1
MPDRNSSKRNQHQHSLSSNNPFRSDDDDDQSPPPVPPLPQYAQNQQFQQPDSPTVPVIRVSNHHDNDNSNTSAPQVHLSS
SSSTPYQTQNSRLHQIDNPPPSITIDEYSSSEPDLPSITINAPEPAVHSQSRLSDTNDPYSPPFYENSSNQDFQQQQQET
RPQRKKSYSSLKPSNHNDQNIDHKDRHISFALDEEDEIHVTTPTPTHQAPQPSANFLSIPTRTNSDDDSDSDSEENNDKK
DSKLARDPSVMKRHRWGTQRHKKGRPKKGSVKRSKSIFSRSEPPHQHVNLPHHVTAKDEVASRKSEDTQTGPEDHGIHRV
YFNLPLPDDMIDPENGLPSVQYPRNKIRTTKYTPLSFIPKNLFFQFKNIANIYFLFIVILGAFPIFGVENAGLASVPIIV
IVAITAIKDAIEDYRRTLLDLEVNNTKTQILSYWHNYNVVDENISLWRRMKKATSRGVFKTLRTIKQSQQKRKAKKDPNY
KPNNEDDLDLRPSRTVQSIYSNHEMQDLERSNKKTHKSRLSTDSEINFRSANPFDDNANRINDENNSKSQQSNPGFKGTI
INPKTVPTGNARFRYDYWKSVRVGDFVRVHNNDEIPADLLILSTSDSDGACYVETKNLDGETNLKVRQALKCGQMIKHSS
DCERAEFWIESEKAHANLYSFNGVCKWRDHSVNPSELNSANRNSQFYDGPIEDDKTICSEPISINNILLRGCSLRNTKWI
IGVVLFTGPETKIMLNAGETPTKKSRISRELNFSVLANFAILFVICFISGLANGIQFSKDDSSIRFFEFGMIGGSAPVAG
LITFWAAVILYQSLVPISLYISIEIVKTIQAFFIYSDVFMYYAPIDYPCTPKSWSISDDLGQIEYIFSDKTGTLTQNVME
FKKCTINGVAYGKAYTEALAGMRKREGIDVDAEGEEMRQQIAEDKVKMINSLRRIHDNPQLYDEDVTFVSSQFVSDIEGE
SGEEQQRACKHFMLALALCHSVVTEANKINPSKIDFKAQSPDEAALVATARDLGFSFIDRTRRGVIVNVQGVEQEYQILN
TLEFNSTRKRMSAIVKLSGSKNLDGSTANDRILLICKGADSVIYSRLRPNGQERLSAETALHLEQFAREGLRTLCIAQRE
LTPEEYQKFNSDYEKASSALENREDKMEEVADALERNLTLLGGTAIEDRLQEGVPQTIALLGKAGIKLWVLTGDKVETAI
NIGFSCNLLDNDMELLILRSDEPTMESVDALLTEYLQKYFQITYSDELIEAAKLNHDPPSPDFAIIVDGDTLKLCLDDNL
KYKFLILCKQCKSILCCRVSPAQKASVVSLVKNTLDVMTLSIGDGANDVAMIQEADVGVGIAGEEGRQAVMSSDYAVGQF
RFLARLLLVHGRWSYKRLAEMIPNFFYKNVVFTFALFWYGVFSSFDGAYLFEYTYVMFFNLAFTSLPVILMGFLDQDVED
RIALAVPQLYRRGILRLEWSQSKFWFYMTDGLYQSLVSFFFPYFMYLGGVSISENGLQLDHRYWLGVSVCTIAVVSCNFY
VLTNQYRWDVASLVICIISCLCVWIWSGIYSSFTASGELYELASQLYSSAAFWAVIFVGIIACMLPHYTVLSIQKIFKPM
DIDIIREQWNLGVFDSVPPITETNYGLTAANALEKRLAGTIYSLGNEHHHEATTKEQDSMSPGSDAIYQKGQGSSDEEGS
DDTKYNAHQKDKSSKRASVYSQSKRQSIGDWVKRKSGHYDHEDLDLSDEENLVDANGQPANIDSSQTSLAGRSQQSLVYP
RRPGGEAGIGGGPSSDSVGSPRMVTPSYISFDTEQLYPESVYEESTHQLTPIHSGAASGPRYATAPSSSSTQPSTIRQIP
APHPLSSSHRPTTSSTNTVSTAYSPTVEFTPSGPEEFHFHHHPDADEPGIDMRNIRKSLEIASASLRNEQRPPRVSRESI
RMSRDLGDDLTTAENLMRTFSRTQYYQQALAEGEGLEDENHPRKHNKMRKFYDKMHFSKK

GO term prediction

Biological Process

GO:0015914 phospholipid transport

Molecular Function

GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005524 ATP binding

Cellular Component

GO:0016021 integral component of membrane