Protein

MCA_04556_1

Length
1,091 amino acids

Gene name: NEO1

Description: Probable phospholipid-transporting ATPase NEO1; role in phospholipid asymmetry of plasma membrane

Browser: contigC:3362516-3365792+

RNA-seq: read pairs 2735, FPKM 30.9, percentile rank 53.6% (100% = highest expression)

Protein function

Annotation:NEO1Probable phospholipid-transporting ATPase NEO1; role in phospholipid asymmetry of plasma membrane
KEGG:K01530E3.6.3.1 phospholipid-translocating ATPase [EC:3.6.3.1]
EGGNOG:0PG6XNEO1P-type ATPase
SGD closest match:S000001310NEO1Probable phospholipid-transporting ATPase NEO1
CGD closest match:CAL0000188465orf19.783Phospholipid-transporting ATPase

Protein alignments

%idAln lengthE-value
MIA_00968_176.26%11120.0MIA_00968_1
A0A0J9X490_GEOCN74.60%10750.0Phospholipid-transporting ATPase OS=Geotrichum candidum GN=BN980_GECA02s07556g PE=3 SV=1
A0A167C9A0_9ASCO70.67%11250.0Phospholipid-transporting ATPase OS=Sugiyamaella lignohabitans GN=NEO1 PE=3 SV=1
A0A1E3PRI2_9ASCO70.39%10640.0Phospholipid-transporting ATPase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48569 PE=3 SV=1
A0A060T2A0_BLAAD72.89%9960.0Phospholipid-transporting ATPase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C23694g PE=3 SV=1
Q6C3B2_YARLI70.74%9740.0Phospholipid-transporting ATPase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01122g PE=3 SV=1
UniRef50_Q6C3B270.74%9740.0Phospholipid-transporting ATPase n=10 Tax=Dikarya TaxID=451864 RepID=Q6C3B2_YARLI
ATC7_YEAST67.26%10170.0Probable phospholipid-transporting ATPase NEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NEO1 PE=1 SV=1
A0A1D8PDD2_CANAL64.71%10060.0Phospholipid-transporting ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.783 PE=3 SV=1
A0A1E4TDL7_9ASCO64.44%9900.0Phospholipid-transporting ATPase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58598 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0046

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 900 1000 1091

Detailed signature matches

  1. Family IPR001757
    P-type ATPase
    1. TIGR01494
  2. Family IPR006539
    P-type ATPase, subfamily IV
    1. TIGR01652
  3. Domain IPR032631
    P-type ATPase, N-terminal
    1. PF16209 (PhoLip_ATP...)
  4. Domain IPR023298
    P-type ATPase, transmembrane domain
    1. SSF81665 (Calcium A...)
  5. Domain IPR008250
    P-type ATPase, A domain
    1. SSF81653 (Calcium A...)
  6. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...
  7. Domain IPR023299
    P-type ATPase, cytoplasmic domain N
    1. SSF81660 (Metal cat...)
    2. G3DSA:3.40.11...
  8. Domain IPR032630
    P-type ATPase, C-terminal
    1. PF16212 (PhoLip_ATP...)
  9. SITE IPR018303
    P-type ATPase, phosphorylation site
    1. PS00154 (ATPASE_E1_E2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:2.70.15...
  3. NON_CYTOPLASM... (N...)
  4. PF00122 (E1-E2_ATPase)
  5. PF13246 (Cation_ATPase)
  6. PR00119 (CATATPASE)
  7. TMhelix
  8. TRANSMEMBRANE (Tran...)
  9. mobidb-lite (disord...)

Protein sequence

>MCA_04556_1
MNNFDIPLHNMNPSSMSVSSDPYYNNDEDDDLIVHAEDSSAPLIRSSNDSSIGRKQRSSSNGGGRSTDNMILKSNPFKHF
FTSIFQKNETAHTPVALRSDRTVSPEMALPKNSRNYTFPTNAISNAKYNAATFLPVILYDQFKFFFNLYFLLVALSQAIP
ALRIGYLSSYIVPLAFVLTVTMSKEAWDDILRRRRDKEANTELYTVLTSERETQIQAKDLKVGNLVRLHKDQRIPADMIL
LQSSESTGESFIKTDQLDGETDWKLRVACALTQPLSASGLCKISITAEHPQKDIHTFLGNLSVSGNSSPLTVDNTLWANT
VLAAGSAIGCVIYTGQDTRQALNTSKARAKTGRLEIEINNLSKILCACVFLLSFGLVAIKGFGEHWYINVMRFLILFSTI
IPVSLRVNLDMAKSVYAYQIEHDKKIPDTIVRTSTIPEDLGRIEYLLTDKTGTLTQNDMEMKKIHVGTVSYTPDTMDEVS
QFMTGDITSLRSRRELGNRVRDIVTTLAICHSVTPSYDDENNSQVEYQAASPDEVAIVKWTASVGLSLYKRDRKSMTLYH
SASQTYLEYEILYVFPFNSDNKRMGIIVRDKAKGEYWFMQKGADTVMTSIVQQNDWLEEETGNMAREGLRTLVIGRKKLH
QAQFDDFKSDYEKASLSMTNRDEQMAKVVSKYLERDLELLGLTGVEDRLQKDMKPSLELLRNAGIKIWMLTGDKVETARC
IAVSSKLVARGQYIQTVVKVKHREVALEHIEFLKRRQDAALLIDGESLSLFLKYYRDEFVAVATVLPAVIACRCTPQQKA
DVAILIKETTKKRVCCIGDGGNDVSMIQAADVGVGIVGKEGKQASLAADFSITQFCHLTKLLVWHGRNSYKRSAKLAQFV
IHRGLIISVCQTVFSISSSFEPLALYQGWLMVGYATVYTMAPVFSLVLDRDVDEDLANLYPELYKELTEGKSLSYKTFFV
WVLVSLYQGTIIQGLSQLFVLYKPSGSEENALFTRMVAVSFTCLLMNELIMVALEIITWNKVMFFSEVITFLIYVVSVPF
LGDYFDLEYVEKFEFYWKCTIITATALIPPWIGKALRRKLKPPNYAKVQQA

GO term prediction

Biological Process

GO:0015914 phospholipid transport

Molecular Function

GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005524 ATP binding

Cellular Component

GO:0016021 integral component of membrane