Protein

MCA_04548_1

Length
1,051 amino acids

Gene name: MET10

Description: Sulfite reductase [NADPH] flavoprotein component; complex converts sulfite into sulfide

Browser: contigC:3340575-3343731-

RNA-seq: read pairs 10049, FPKM 118.0, percentile rank 81.6% (100% = highest expression)

Protein function

Annotation:MET10Sulfite reductase [NADPH] flavoprotein component; complex converts sulfite into sulfide
KEGG:K00380cysJ sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]
EGGNOG:0PH6JFG08463.1Sulfite reductase
SGD closest match:S000001926MET10Sulfite reductase [NADPH] flavoprotein component
CGD closest match:CAL0000199215MET10Sulfite reductase subunit alpha

Protein alignments

%idAln lengthE-value
MIA_04637_167.55%10600.0MIA_04637_1
A0A0J9X6R9_GEOCN61.38%10590.0Similar to Saccharomyces cerevisiae YFR030W MET10 Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide OS=Geotrichum candidum GN=BN980_GECA04s01506g PE=4 SV=1
A0A167ETD9_9ASCO54.58%10480.0Sulfite reductase subunit alpha OS=Sugiyamaella lignohabitans GN=MET10 PE=4 SV=1
UniRef50_A0A167ETD954.58%10480.0Sulfite reductase subunit alpha n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167ETD9_9ASCO
A0A060SZW7_BLAAD49.24%10580.0ARAD1C03850p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C03850g PE=4 SV=1
Q6C5P4_YARLI48.85%10440.0YALI0E16368p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16368g PE=4 SV=1
A0A1E3PHZ7_9ASCO46.02%10670.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83141 PE=4 SV=1
A0A1D8PIF6_CANAL42.75%11040.0Sulfite reductase subunit alpha OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MET10 PE=4 SV=1
A0A1E4TLN6_9ASCO42.47%9960.0Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11548 PE=4 SV=1
MET10_YEAST42.29%10760.0Sulfite reductase [NADPH] flavoprotein component OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET10 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0180

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1051

Detailed signature matches

  1. Domain IPR009014
    Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
    1. G3DSA:3.40.50...
    2. SSF52922 (TK C-term...)
  2. Domain IPR002869
    Pyruvate-flavodoxin oxidoreductase, central domain
    1. SSF53323 (Pyruvate-...)
  3. Domain IPR019752
    Pyruvate/ketoisovalerate oxidoreductase, catalytic domain
    1. G3DSA:3.40.92...
    2. PF01558 (POR)
  4. Domain IPR017938
    Riboflavin synthase-like beta-barrel
    1. SSF63380 (Riboflavi...)
  5. Domain IPR017927
    Ferredoxin reductase-type FAD-binding domain
    1. PS51384 (FAD_FR)
  6. Domain IPR003097
    FAD-binding, type 1
    1. PF00667 (FAD_binding_1)
  7. Domain IPR001433
    Oxidoreductase FAD/NAD(P)-binding
    1. PF00175 (NAD_binding_1)
  8. Domain IPR001709
    Flavoprotein pyridine nucleotide cytochrome reductase
    1. PR00371 (FPNCR)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.30.10
  2. G3DSA:3.40.50.80
  3. SSF52343 (Ferredoxi...)
  4. cd06207 (CyPoR_like)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. catalytic residues...
  4. NAD binding pocket...
  5. phosphate binding ...
  6. beta-alpha-beta st...

Protein sequence

>MCA_04548_1
MSENIFNHPFPVSGNLESITKNSYTTQQTEIQKIAYLLSGSIFSYSTESFNLDSSISLWTKFAQNNIHGFVPTLTHLQTR
SGAASILLGYSKHHDKQEALEATPIAKTVIASTATLGAMKPVLNQYVINPSKSSPLTFDIAAIDYDAQSGSLVTDYASAL
ETVNDLGLGLIASHTLQDGPAVSILSTALSSVLPTAHIYGGIRAIQENSKTEQTLTSLEVADAFPKLAAVVKSDASLTEN
IQNLFAAANAEFGLKLAPFEYTGSARPQIVIVTFGSTESVLASHIVKRLGQSGQDVGTIAVRLYSPFLDEEFFKVLPEST
KKLIVLGQVKDEESVSSDFTHSPLYLDISTALYMKKGLSSLKVVDHKYSRSKIWSEHEFYSLFSSSSIPSSRADIKEVVF
WDTDNSSIIDTPARITHTISLDGSSSVSHFTKFDNEATGGVIETQLKISNTSTINAPYPVENADLVLINNSKVTSEFDVL
KNVKPGAKAIISSSPDIEEINKNYDDNFKKQAAAKEILLFAVNFDAIGDEAETQGRTQSMVYQIAFWKAFSPELTVNQIT
TKIVTANGVDTELVAATVARLVEKVVETAFFTIEIPKEWSEIETEASVQPPSINRISFLPNEPLSEEEIEAKPKSSTNWV
EAAKQLVFSEAYDASTELRPDLPVKNFIVKVKENKRVTPAEYERHIFHFELDITGTGLKYDIGEALGVHARNNAEQVEDF
LTAYGIELDSVVSVPSRDNSEIYETRTAYQAFRDNLDIFGKPPKKFFESLATYAKDEKEKAHLEKLAGAEGAEELKKRAE
VDFDTYADILLEFKSAHLTLGELVELVAPLKRREYSIASSQHMHPNEVHLLIVVVDWVDSRGRKRYGQCSKYLSELPVGS
ELVVSVKPSVMKLPPTPQQPIIMSGLGTGLAPFKALIEEKVWQKEQGMEIGEIYLYLGSRHQREEYLYGEIWEAYKDAGI
ITHIGAAFSRDQPQKIYIQDKIRSSIDQLVSAFVDKKGYFYLCGPTWPVPDITACLEDILKKDAAVKNIKIDTAKEIEEL
KEAGRYVLEVY

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors

Cellular Component

None predicted.