Protein

MCA_04541_1

Length
544 amino acids

Gene name: PUT4

Description: Proline-spefic permease

Browser: contigC:3320730-3322486-

RNA-seq: read pairs 2787, FPKM 63.2, percentile rank 70.4% (100% = highest expression)

Protein function

Annotation:PUT4Proline-spefic permease
KEGG:K16261YAT yeast amino acid transporter
EGGNOG:0QDM5PGUG_04500permease
SGD closest match:S000005875PUT4Proline-specific permease
CGD closest match:CAL0000194693DIP5Dip5p

Protein alignments

%idAln lengthE-value
A0A0J9X6H5_GEOCN73.16%5440.0Similar to Saccharomyces cerevisiae YOR348C PUT4 Proline permease, required for high-affinity transport of proline OS=Geotrichum candidum GN=BN980_GECA04s03530g PE=4 SV=1
MIA_00966_175.41%5530.0MIA_00966_1
A0A060T9M7_BLAAD69.52%5380.0ARAD1B00352p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B00352g PE=4 SV=1
A0A1E3PGR2_9ASCO67.23%5370.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71070 PE=4 SV=1
Q6CF79_YARLI64.94%5590.0YALI0B09537p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B09537g PE=4 SV=1
UniRef50_Q9URZ364.12%5490.0Probable proline-specific permease put4 n=23 Tax=Ascomycota TaxID=4890 RepID=PUT4_SCHPO
PUT4_YEAST49.81%5344e-166Proline-specific permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUT4 PE=2 SV=2
A0A167EFR2_9ASCO65.70%3445e-167Proline permease PUT4 OS=Sugiyamaella lignohabitans GN=PUT4 PE=4 SV=1
A0A1D8PCR4_CANAL38.61%5186e-110Dip5p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DIP5 PE=4 SV=1
A0A1E4TD58_9ASCO39.05%5662e-108Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32842 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0766

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 544

Detailed signature matches

  1. Family IPR002293
    Amino acid/polyamine transporter I
    1. PIRSF006060 (AA_tra...)
  2. Domain IPR004841
    Amino acid permease/ SLC12A domain
    1. PF00324 (AA_permease)
  3. SITE IPR004840
    Amino acid permease, conserved site
    1. PS00218 (AMINO_ACID...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MCA_04541_1
MSIENEKRVDSMLTDLPSDSNSTENGQVISDHPGLHRGLKSRHVQLIALGGCIGTGLFVGSGAALYNSGPASLFLSYCIM
SFVIWSIMNCLGEMTTYLPVEGVSPTMFVNRFADKSLGFATGWNYWYSYAFLVPSEITAAAIVIEYWTKDVPTAAWIAII
WVIIVALNLFFVQLFGETEFWFASIKIIAIVGLIILGVVIFFGGTPTHDRLGFRYWKHDAFKEYIVTGASGRFCGFWNAV
IRSGFSFIMSPELITISAGETEAPRRNVPKATNRFIYRLVFFYIVGSLVISCIVSSSDPLLMNEHHDASASPFVIGITNA
GIPVLNHIINAVILTSAWSAGNSFLFAGSRTLFSLAQNGLAPKIFKWCTPWGVPLPAVAFTASIALLSFLNVSSSSADVF
TWFTNLSTVSGFLAWVCVCISYLRWRKAMKFQGVDDTRPYKTVWQPYTTWITLIFVAILALTNGFQVFVGGTFKGSDFVA
AYITIPLFFILYVGHKIWHKNWRWFIPTEEVDVLSGLDEVEKVEAMSPPREPRNWLEKVWFWIA

GO term prediction

Biological Process

GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport

Molecular Function

GO:0015171 amino acid transmembrane transporter activity

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane