Protein

MCA_04533_1

Length
412 amino acids

Gene name: CDC12

Description: Cell division control protein 12; septin

Browser: contigC:3302377-3303752-

RNA-seq: read pairs 2747, FPKM 82.2, percentile rank 75.7% (100% = highest expression)

Protein function

Annotation:CDC12Cell division control protein 12; septin
KEGG:K16948CDC12 cell division control protein 12
EGGNOG:0PGZ3PGUG_04327Cell division control protein 12
SGD closest match:S000001149CDC12Cell division control protein 12
CGD closest match:CAL0000175669CDC12Septin

Protein alignments

%idAln lengthE-value
MIA_02038_175.53%4210.0MIA_02038_1
A0A0J9XJK5_GEOCN75.26%3920.0Similar to Saccharomyces cerevisiae YHR107C CDC12 Component of the septin ring neck that is required for cytokinesis OS=Geotrichum candidum GN=BN980_GECA22s01297g PE=3 SV=1
Q6C7L3_YARLI66.08%3950.0YALI0D27148p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D27148g PE=3 SV=2
A0A060TBS3_BLAAD65.89%3870.0ARAD1D37158p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37158g PE=3 SV=1
UniRef50_E5A95764.80%3920.0Similar to cell division control protein 12 n=40 Tax=Fungi TaxID=4751 RepID=E5A957_LEPMJ
A0A1E3PI52_9ASCO64.69%3880.0Septin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_59423 PE=3 SV=1
A0A167EQI5_9ASCO62.36%3642e-168Septin CDC12 OS=Sugiyamaella lignohabitans GN=CDC12 PE=3 SV=1
A0A1E4THI7_9ASCO58.70%3852e-161Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_61460 PE=3 SV=1
A0A1D8PCY5_CANAL55.47%4111e-159Septin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC12 PE=3 SV=1
CDC12_YEAST53.13%3991e-142Cell division control protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC12 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0567

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 412

Detailed signature matches

  1. Family IPR016491
    Septin
    1. cd01850 (CDC_Septin)
    2. PIRSF006698 (Septin)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR030379
    Septin-type guanine nucleotide-binding (G) domain
    1. PF00735 (Septin)
    2. PS51719 (G_SEPTIN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...

Residue annotation

  1. G1 box cd01850
  2. GTP/Mg2+ binding s...
  3. Switch I region cd...
  4. G2 box cd01850
  5. G3 box cd01850
  6. Switch II region c...
  7. G4 box cd01850
  8. G5 box cd01850

Protein sequence

>MCA_04533_1
MLAQKPQPIHNIKSNMTASESLVDAEIGVANLPNQRFKIVAKRGATFTIMLAGESGLGKTTFVNTLFATSVKTPVDNKQR
YTTSIRKNVEIGITKADLEEHFFHVRLNIIDTPGFGDNVNNRDAWQPIVEFIDDQHEAYLRQEQQPDRRNIIDMRVHACL
YFIRPTGHSLKPLDIEAMRELSTRVNLIPVIAKADTLSPEEIRDFKVRIREILTAQKINIYKPSYEDVFDPLDVKGSNTY
TEEQINSNDEARAIKDLIDTMPFSVIGSENEVELSDGRIVRGRKYLWGVAEVENEKHCDFMKLRLLLIRSHMLDLIQSTE
DVHYENYRAKQMETRKLGDPRPRKWDNPKYKKEEEELRKTFTNQVRVEEQRFRQWEQNLINERDRLNRDLEETHSAIRKL
EDEIEQLSMRRR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.