Protein

MCA_04507_1

Length
812 amino acids

Gene name: DPB2

Description: DNA polymerase epsilon subunit B

Browser: contigC:3209652-3212153+

RNA-seq: read pairs 770, FPKM 11.7, percentile rank 28.7% (100% = highest expression)

Protein function

Annotation:DPB2DNA polymerase epsilon subunit B
KEGG:K02325POLE2 DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
EGGNOG:0PFPNDPB2DNA polymerase epsilon subunit B
SGD closest match:S000006379DPB2DNA polymerase epsilon subunit B
CGD closest match:CAL0000187591DPB2DNA polymerase epsilon noncatalytic subunit

Protein alignments

%idAln lengthE-value
MIA_01096_152.09%8390.0MIA_01096_1
A0A0J9X403_GEOCN41.87%7690.0Similar to Saccharomyces cerevisiae YPR175W DPB2 Second largest subunit of DNA polymerase II (DNA polymerase epsilon) OS=Geotrichum candidum GN=BN980_GECA02s03123g PE=4 SV=1
UniRef50_A0A0J9X40341.87%7694e-179Similar to Saccharomyces cerevisiae YPR175W DPB2 Second largest subunit of DNA polymerase II (DNA polymerase epsilon) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X403_GEOCN
A0A060T8D2_BLAAD36.12%7531e-153ARAD1C35948p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35948g PE=4 SV=1
A0A161HIM0_9ASCO36.45%7605e-152Dpb2p OS=Sugiyamaella lignohabitans GN=DPB2 PE=4 SV=1
A0A1E3PJB3_9ASCO36.75%5852e-104Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5169 PE=4 SV=1
DPB2_YARLI35.33%5522e-97DNA polymerase epsilon subunit B OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DPB2 PE=3 SV=1
A0A1E4TFQ3_9ASCO34.43%5464e-90Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_108250 PE=4 SV=1
A0A1D8PU38_CANAL32.31%6166e-88DNA polymerase epsilon noncatalytic subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DPB2 PE=4 SV=1
DPB2_YEAST31.94%5764e-82DNA polymerase epsilon subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DPB2 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3274

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 812

Detailed signature matches

  1. Domain IPR007185
    DNA polymerase alpha/epsilon, subunit B
    1. PF04042 (DNA_pol_E_B)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_04507_1
MTDSKRESVFRKKPNKLNQARSKSTQRQQPVQQRLSFNSSIPDHSPSPSSPAPSAYSSPRPSIYDAPATLPIELSLTQLR
PIAYRIFSKKHGLNLKTSGLQTLADFIGKRFGLEWRGTASLKFMDDVAKLWKQEDRGLFVEKEQLEAIIKEVLDLSQSMM
SSRNQSINNAQPNGSTTTDNGGIRQGSLLNMFNSQVAQKSDTIVEGNNNQSDSTLDLIKSFDTNIIAAKLAKQNEISWTD
YFKIIDSFSLPPFYYNSRQKNFILKQHGATLLNPASSRLSYFLNRYHLIYDSLIRLEIFQSSSFNKSISLVGKVEDDFLS
TVTPINSLLGKEGNAFTIMGLLSVGSNGNYWLQDATGKVELEIESHALPEPGCYIVPGCILIVEGLADLEHFVVTSMRHP
PCESRQSFRRNFGYLDFLGSHLIQPQNPKNAKPTRIDRTLEQRLEEKVFLDHRIYFLGCNMFLDKPQTLDSLRKLFTRIK
AEVLVDSLTPLAFVFFGPFLSKAFQPTGSSSPYKDGMDMLAQILSEFPELFQSTAKLIFVPGDGDPWESTFSAGAPSSWP
SKRIPATLTTRVSRIAPNLVSFSSNPSRLTYLSQELLFVRDNVGARLRRNQVFFPVLDKRLNEIAEQTHKASSSSQTQKH
RATVRKSRQTGVIDSDDSDIEEIEELNNELEQVVLDIDTDGSSSSAAAIVKNREMQRLMQESRSKNDASGIIDTVDPETA
EARKVVKTLLDQRTLSPFSSNIRPVYWDYEHALNLTPLPTLLVLCDPTTPRFKATYHGCITVNPGQLIDNNQINWVEYSP
GTKSIAERTMYL

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity

Cellular Component

None predicted.