MCA_04501_1

Protein

Length

214 amino acids

Gene name: SEC22

Description: Protein transport protein SEC22

Browser: contigC:3195159-3195969-

RNA-seq: read pairs 1489, FPKM 85.6, percentile rank 76.3% (100% = highest expression)

Protein function

Annotation:		SEC22	Protein transport protein SEC22
KEGG:	K08517	SEC22	vesicle transport protein SEC22
EGGNOG:	0PHQQ	SEC22	Protein transport protein SEC22
SGD closest match:	S000004258	SEC22	Protein transport protein SEC22
CGD closest match:	CAL0000189362	SEC22	SNAP receptor

Protein alignments

	%id	Aln length	E-value
MIA_01102_1	76.12%	201	9e-107	MIA_01102_1
A0A0J9X2M3_GEOCN	70.10%	204	8e-93	Similar to Saccharomyces cerevisiae YLR268W SEC22 R-SNARE protein OS=Geotrichum candidum GN=BN980_GECA01s03915g PE=3 SV=1
A0A060T2J2_BLAAD	64.04%	203	5e-86	ARAD1A08800p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A08800g PE=3 SV=1
A0A1E3PN57_9ASCO	64.53%	203	2e-85	Snare-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46054 PE=3 SV=1
SEC22_YARLI	63.37%	202	3e-84	Protein transport protein SEC22 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SEC22 PE=3 SV=1
A0A1D8PSL3_CANAL	63.05%	203	1e-78	SNAP receptor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEC22 PE=4 SV=1
A0A1E4TLS5_9ASCO	57.79%	199	3e-74	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_90665 PE=3 SV=1
UniRef50_Q9Y7L0	58.29%	199	3e-68	Protein transport protein sec22 n=64 Tax=Eukaryota TaxID=2759 RepID=SEC22_SCHPO
SEC22_YEAST	49.01%	202	1e-57	Protein transport protein SEC22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC22 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0257

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 125
Longin-like domain (IPR011012)
Longin domain (IPR010908)
131 - 212
Synaptobrevin (IPR001388)

1 20 40 60 80 100 120 140 160 180 200 214

Detailed signature matches

IPR011012

Longin-like domain
1. SSF64356 (SNARE-like)
  
  1 - 125
  
  SUPERFAMILY
  SSF64356 (SNARE-like)
IPR010908

Longin domain
1. PS50859 (LONGIN)
  
  6 - 117
  
  PROSITE profiles
  PS50859 (LONGIN)
2. PF13774 (Longin)
  
  36 - 114
  
  Pfam
  PF13774 (Longin)
3. SM01270 (Longin_2)
  
  34 - 116
  
  SMART
  SM01270 (Longin_2)
IPR001388

Synaptobrevin
1. PF00957 (Synaptobrevin)
  
  131 - 212
  
  Pfam
  PF00957 (Synaptobrevin)
2. PS50892 (V_SNARE)
  
  132 - 192
  
  PROSITE profiles
  PS50892 (V_SNARE)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1 - 188

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
Coil

133 - 153

COILS
Coil (Coil)
G3DSA:1.20.5.110

142 - 214

GENE3D
G3DSA:1.20.5.110 (G3DSA:1.20.5.110)
G3DSA:3.30.45...

1 - 141

GENE3D
G3DSA:3.30.450.50 (G3DSA:3.30.450.50)
NON_CYTOPLASM... (N...)

213 - 214

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SSF58038 (SNARE fus...)

127 - 193

SUPERFAMILY
SSF58038 (SNARE fusion complex)
TMhelix

190 - 212

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

189 - 212

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
cd15866 (R-SNARE_SEC22)

131 - 193

CDD
cd15866 (R-SNARE_SEC22)

Residue annotation

heterotetramer int...

132N

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

133L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

134D

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

136L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

137N

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

139E

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

140L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

141Q

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

142D

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

143V

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

144T

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

146V

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

147M

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

148N

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

150N

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

153D

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

154L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

156Y

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

157R

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

158G

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

160S

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

161L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

162D

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

163K

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

164M

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

165Q

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

167L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

168S

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

169S

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

170N

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

171L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

172R

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

174E

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

175S

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

176K

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

177K

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

178Y

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

179M

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

181K

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

182A

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

183Q

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

184R

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

185I

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

186N

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

188E

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

189A

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)

190L

heterotetramer interface
132N, 133L, 134D, 136L, 137N, 139E, 140L, 141Q, 142D, 143V, 144T, 146V, 147M, 148N, 150N, 153D, 154L, 156Y, 157R, 158G, 160S, 161L, 162D, 163K, 164M, 165Q, 167L, 168S, 169S, 170N, 171L, 172R, 174E, 175S, 176K, 177K, 178Y, 179M, 181K, 182A, 183Q, 184R, 185I, 186N, 188E, 189A, 190L
CDD
cd15866 (R-SNARE_SEC22)
zero layer cd15866

157R

zero layer
157R
CDD
cd15866 (R-SNARE_SEC22)

Protein sequence

>MCA_04501_1
MVLSTYIARVEDGNPLCASVDEDSNDLLEDQKRKIKLLLRKITPNSEPRASIESDQFYIFYLINNGIVYFCITDRSYPSK
LAFSYLEEISKEFNTSYGTEALTVSKPFSFMKFDNFLQKTKKIYQDTRATSNLDRLNAELQDVTRVMNKNIEDLIYRGDS
LDKMQDLSSNLRSESKKYMRKAQRINLEALIRQYIPVIGVSLFFLFIIWWMFLR

GO term prediction

Biological Process

GO:0006810 transport
GO:0016192 vesicle-mediated transport

Molecular Function