Protein

MCA_04482_1

Length
192 amino acids

Gene name: ARL3

Description: ADP-ribosylation factor-like protein 3

Browser: contigC:3150521-3151460-

RNA-seq: read pairs 576, FPKM 36.9, percentile rank 58.6% (100% = highest expression)

Protein function

Annotation:ARL3ADP-ribosylation factor-like protein 3
KEGG:K07952ARFRP1 ADP-ribosylation factor related protein 1
EGGNOG:0PJ7UARL3ADP-ribosylation factor family protein
SGD closest match:S000005972ARL3ADP-ribosylation factor-like protein 3
CGD closest match:CAL0000188016ARL3Arf family GTPase

Protein alignments

%idAln lengthE-value
A0A0J9X8N8_GEOCN72.86%1992e-100Similar to Saccharomyces cerevisiae YPL051W ARL3 GTPase of the Ras superfamily required to recruit Arl1p to the Golgi OS=Geotrichum candidum GN=BN980_GECA05s03211g PE=3 SV=1
A0A167C1Z8_9ASCO71.36%1995e-99Arf family GTPase ARL3 OS=Sugiyamaella lignohabitans GN=ARL3 PE=3 SV=1
UniRef50_A0A167C1Z871.36%1991e-95Arf family GTPase ARL3 n=34 Tax=Opisthokonta TaxID=33154 RepID=A0A167C1Z8_9ASCO
A0A060T4H0_BLAAD65.83%1992e-90ARAD1C04224p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C04224g PE=3 SV=1
ARL3_YEAST60.91%1976e-79ADP-ribosylation factor-like protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARL3 PE=1 SV=1
MIA_05886_177.93%1453e-76MIA_05886_1
Q6CAG2_YARLI62.96%1891e-75YALI0D02995p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D02995g PE=3 SV=2
A0A1E4TGM2_9ASCO54.31%1972e-70Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_112103 PE=3 SV=1
A0A1E3PLF3_9ASCO64.49%1385e-60p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45779 PE=3 SV=1
A0A1D8PF23_CANAL33.33%2529e-43Arf family GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARL3 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4573
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 180 192

Detailed signature matches

  1. Family IPR006689
    Small GTPase superfamily, ARF/SAR type
    1. PF00025 (Arf)
  2. Family IPR024156
    Small GTPase superfamily, ARF type
    1. PS51417 (ARF)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. PR00449 (RASTRNSFRMNG)
  4. SM00173 (ras_sub_4)
  5. SM00175 (rab_sub_5)
  6. SM00177 (arf_sub_2)
  7. SM00178 (sar_sub_1)
  8. cd04160 (Arfrp1)

Residue annotation

  1. G1 box cd04160
  2. putative GAP inter...
  3. GTP/Mg2+ binding s...
  4. Switch I region cd...
  5. G2 box cd04160
  6. putative GEF inter...
  7. putative effector ...
  8. interswitch region...
  9. G3 box cd04160
  10. Switch II region c...
  11. G4 box cd04160
  12. G5 box cd04160

Protein sequence

>MCA_04482_1
MYHLVKGIYTSFTRKEGLDNAGKTTLLEQLKKEYSDSKKGLPPDRIAPTVGQNIGHITINGVLLRLWDIGGQENLRSMWE
SYYKEAHAVVFVVDSADRERLEECKAALETVVTNEETEGVPILMLANKQDKEDRMEVEDIKEIFNVIAEKMGARDSRVLP
ISALTGEGIESATDWLVTRLVRNKQYRPPNLR

GO term prediction

Biological Process

GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular