Protein

MCA_04469_1

Length
331 amino acids

Gene name: GPI12

Description: N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

Browser: contigC:3127230-3128226+

RNA-seq: read pairs 4963, FPKM 184.7, percentile rank 87.1% (100% = highest expression)

Protein function

Annotation:GPI12N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
KEGG:K03434PIGL N-acetylglucosaminylphosphatidylinositol deacetylase [EC:3.5.1.89]
EGGNOG:0PF9BGPI12N-acetylglucosaminylphosphatidylinositol deacetylase
SGD closest match:S000004894GPI12N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
CGD closest match:CAL0000183720orf19.4903N-acetylglucosaminylphosphatidylinositol deacetylase

Protein alignments

%idAln lengthE-value
MIA_01160_142.46%3256e-72MIA_01160_1
A0A0J9XE11_GEOCN37.64%2712e-46Similar to Saccharomyces cerevisiae YMR281W GPI12 ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly OS=Geotrichum candidum GN=BN980_GECA11s02463g PE=4 SV=1
UniRef50_A0A0J9XE1137.64%2714e-43Similar to Saccharomyces cerevisiae YMR281W GPI12 ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE11_GEOCN
Q6C513_YARLI36.27%2953e-46YALI0E21934p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21934g PE=4 SV=1
A0A1E3PK55_9ASCO33.77%3025e-44LmbE-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82775 PE=4 SV=1
A0A167EWW1_9ASCO30.45%3122e-36Gpi12p OS=Sugiyamaella lignohabitans GN=GPI12 PE=4 SV=1
A0A060TGB5_BLAAD32.09%2962e-30ARAD1D22198p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22198g PE=4 SV=1
GPI12_YEAST27.21%2946e-22N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPI12 PE=1 SV=2
A0A1D8PEU2_CANAL24.04%3372e-19N-acetylglucosaminylphosphatidylinositol deacetylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4903 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3902
Predicted cleavage: 30

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 331

Detailed signature matches

  1. Family IPR003737
    N-acetylglucosaminyl phosphatidylinositol deacetylase-related
    1. PF02585 (PIG-L)
  2. Domain IPR024078
    Putative deacetylase LmbE-like domain
    1. G3DSA:3.40.50...
    2. SSF102588 (LmbE-like)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MCA_04469_1
MPTPKPPTAPVASAAQQPSTTRPRQQARPKPPIAMIVMTLMTLIPSILWGFALKQAAKYPYPSSLQNSSVVLLTAHPDDE
AMFFGPTIHKLLRENNTVSLLCFSTGDNDGIGHIRTKELFESLNYFTKTTTANVTVEAEGDDEITEKSIDITNKLRLLDI
IDEPKLFPDSMTVEWDTKEVQSKILEVLREKEVLRENSGPVNILTFDSYGISGHINHKALYTAANALVHDPDLETKLNLW
VLKSVPIYRKYLYVVDAAIQLFLKSNNLLPSVNALESISTTESVVIVSETKDYSDTYAAMSKAYKSQMKWFRYLWMVFSR
YMVVNDIYRIL

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.