Protein

MCA_04465_1

Length
413 amino acids


Gene name: FPR4

Description: FK506-binding protein

Browser: contigC:3119161-3120403-

RNA-seq: read pairs 7187, FPKM 214.5, percentile rank 88.9% (100% = highest expression)

Protein function

Annotation:FPR4FK506-binding protein
KEGG:K14826FPR3_4 FK506-binding nuclear protein [EC:5.2.1.8]
EGGNOG:0PFCGFPR4Peptidyl-prolyl cis-trans isomerase
SGD closest match:S000004539FPR3FK506-binding nuclear protein
CGD closest match:CAL0000196167FPR3FK506-binding protein 3

Protein alignments

%idAln lengthE-value
MIA_01170_179.03%1241e-65MIA_01170_1
A0A060TH27_BLAAD75.83%1203e-56FK506-binding protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27742g PE=3 SV=1
A0A0J9XF35_GEOCN72.44%1275e-54FK506-binding protein OS=Geotrichum candidum GN=BN980_GECA11s02386g PE=3 SV=1
UniRef50_A0A0J9XF3572.44%1279e-51FK506-binding protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XF35_GEOCN
A0A1E3PKV9_9ASCO69.35%1243e-53FK506-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82790 PE=3 SV=1
FKBP3_YEAST64.84%1285e-49FK506-binding nuclear protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FPR3 PE=1 SV=2
A0A167CNA6_9ASCO63.71%1244e-48FK506-binding protein OS=Sugiyamaella lignohabitans GN=FPR4 PE=3 SV=1
FKBP3_YARLI63.71%1249e-46FK506-binding protein 3 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=FPR3 PE=3 SV=1
A0A1E4TIP7_9ASCO64.41%1182e-45Peptidylprolyl isomerase (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29984 PE=4 SV=1
FKBP3_CANAL57.58%1324e-42FK506-binding protein 3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FPR3 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0785

Protein family membership

Domains and repeats

1 50 100 150 200 250 300 350 413

Detailed signature matches

    1. PIRSF001473 (FK506-...)
    1. PF00254 (FKBP_C)
    2. PS50059 (FKBP_PPIASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF54534 (FKBP-like)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_04465_1
MSSEIPEQTLIPVATYSLQIPAGEPASLIEATEGEFVTVKLTLAAIDPTSSESKEPTVVRMITRPRFLDYDDEDDLDSSD
DEDEEDEEEEEEEEEEKPKKKSKSPKKKAEDDEEMEDDDEDEDDDEDDEDDSLETQSVVCTLSPTSLFQQNIELYLTPNE
EVVFFADGPHTVYLNGNIVTHPYDDEESSDDEDDYDSDEEDFDLSEYMRQGDDYDLSPDEDELDQSSRIEEINDEEEEEE
KPKKNAEKKNSKKRAAEEVESPAPKAEKEKSKKQKKEEEKKVSFSKELEQGPTPTKSKAKEPTVKKLEGNVTIEDKKIGT
GPIAKKGDKVSVRYIGKLKNGKTFDSNTQGKPFQFKLGAGQVIKGWDVGVAGMAVKGERRIVVPAPMAYGNQSLPGIPSG
STLIFDVKLVGIK

GO term prediction

Biological Process

GO:0000412 histone peptidyl-prolyl isomerization
GO:0018208 peptidyl-proline modification

Molecular Function

GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005528 FK506 binding

Cellular Component

GO:0005730 nucleolus