Protein

MCA_04454_1

Length
405 amino acids

Browser: contigC:3093335-3094553-

RNA-seq: read pairs 2017, FPKM 61.4, percentile rank 69.8% (100% = highest expression)

Protein function

KEGG:K00004BDH (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303]
EGGNOG:0PFVVPGUG_04554Dehydrogenase
SGD closest match:S000000057BDH2Probable diacetyl reductase [(R)-acetoin forming] 2
CGD closest match:CAL0000197952IFE1Putative dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_04181_175.62%4020.0MIA_04181_1
A0A0J9XAG9_GEOCN66.42%4020.0Similar to Saccharomyces cerevisiae YAL060W BDH1 NAD-dependent (R,R)-butanediol dehydrogenase OS=Geotrichum candidum GN=BN980_GECA06s00219g PE=3 SV=1
A0A1E3PKZ9_9ASCO50.00%3745e-130GroES-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82958 PE=4 SV=1
UniRef50_A0A1E3PFJ951.17%3851e-125Glycerol dehydrogenase n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PFJ9_9ASCO
BDH2_YEAST41.21%3816e-103Probable diacetyl reductase [(R)-acetoin forming] 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BDH2 PE=1 SV=1
A0A1D8PDC5_CANAL40.97%3932e-96Putative dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IFE1 PE=3 SV=1
A0A1E4TJU6_9ASCO41.89%3705e-90Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30303 PE=3 SV=1
A0A167EEZ6_9ASCO30.99%3551e-40L-iditol 2-dehydrogenase SOR1 OS=Sugiyamaella lignohabitans GN=SOR1 PE=3 SV=1
Q6KAV2_BLAAD30.75%3357e-34ARAD1D37840p OS=Blastobotrys adeninivorans GN=axdh1 PE=3 SV=1
Q6C648_YARLI26.76%3551e-31YALI0E12463p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12463g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0407

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 405

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR020843
    Polyketide synthase, enoylreductase domain
    1. SM00829 (PKS_ER_nam...)
  3. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  6. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.90.18...
  3. cd08233 (butanediol...)

Residue annotation

  1. catalytic Zn bindi...
  2. putative NAD(P) bi...

Protein sequence

>MCA_04454_1
MKQLQLFGQNDLRVVDSASMPEIKNPDEVLIKVGFCGICGTDLHEYVSGPNFGPQPGEKHEHSGVELPLCMGHEFVGTIV
QTGDNVTRVKQGDRVCVDVSFACKEQGVSPVCYACKQGSPNACVRLCLRGLSASNGGLAQYSVVQEHSVHKLPDNVPMDI
GAMVQPMSISWHAVRISEIKKGQTALVIGAGPIGIACILALQGHGASHIIVSEPAEIRRKQALELGVDHVIDPLSFKSTD
ECVSKIQELTPPDHEGVDFAYDCGGMQATLDLAIEALKMGGTAVNIAVWPSNKTATITPMAITKREKRYMGSMGLTALDM
EQVLEAFGSGKMSMDRARKMITSKVHLDEAVEGGFEQLNKNKDKHIKILIAPNGMKNGIPPNEAASHLPNGIDVISWQKE
FELEN

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.