Protein

MCA_04424_1

Length
1,548 amino acids

Gene name: XRN1

Description: 5'-3' exoribonuclease 1

Browser: contigC:3011397-3016273+

RNA-seq: read pairs 3582, FPKM 28.6, percentile rank 51.3% (100% = highest expression)

Protein function

Annotation:XRN15'-3' exoribonuclease 1
KEGG:K12618XRN1 5'-3' exoribonuclease 1 [EC:3.1.13.-]
EGGNOG:0PGRHFGSG_067995'-3' exoribonuclease
SGD closest match:S000003141XRN15'-3' exoribonuclease 1
CGD closest match:CAL0000192354KEM15'-3' exoribonuclease 1

Protein alignments

%idAln lengthE-value
MIA_03918_156.85%13860.0MIA_03918_1
A0A060TFW6_BLAAD51.03%13130.05'-3' exoribonuclease 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26334g PE=3 SV=1
A0A0J9YH98_GEOCN51.73%12720.05'-3' exoribonuclease 1 OS=Geotrichum candidum GN=BN980_GECA01s01286g PE=3 SV=1
UniRef50_A0A0J9YH9851.73%12720.05'-3' exoribonuclease 1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9YH98_GEOCN
A0A167CV40_9ASCO48.67%12040.05'-3' exoribonuclease 1 OS=Sugiyamaella lignohabitans GN=XRN1 PE=3 SV=1
Q6CAZ5_YARLI44.21%13210.05'-3' exoribonuclease 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23144g PE=3 SV=1
A0A1D8PFP3_CANAL44.38%12890.05'-3' exoribonuclease 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KEM1 PE=3 SV=1
XRN1_YEAST42.43%13480.05'-3' exoribonuclease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=XRN1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1899

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1548

Detailed signature matches

  1. Family IPR016494
    5'-3' exoribonuclease 1
    1. PIRSF006743 (Exonuc...)
  2. Domain IPR029060
    PIN domain-like
    1. G3DSA:3.40.50...
  3. Domain IPR004859
    Putative 5-3 exonuclease
    1. PF03159 (XRN_N)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_04424_1
MGMYISERWPLISQLVNDNQIPEFDNLYLDMNSIIHNSTHKNGDATFQITEEEMYAQIFNYIEHLFVLIKPKKLFYMAID
GVAPRAKMNQQRARRFKSAQDAEEERKKAVEKGLEIPKDPFDSNAITPGTLFMEKLTAHLKYFIHKKISTDSSWQNVEII
LSGHEVPGEGEHKIMAHIRHAKAQPDYPSNLRHCLYGLDADLIMLGLSSHDPHFAILREEVLFTPEAKKPKELSQQNFYL
LHISIVREYLELEFEGISEEISFPYDFERILDDFILLNFFVGNDFLPELPSLLINDGALPIVIKTYQEFLRSSDGYLTER
GEINFPRLGQWLDQFTDFEHKLFEKQAVDLEWLNEELDLITREERLDAVESHHFTLTPLQKKLLGPISDFASRANSIPKP
DPMEDDIPIYTIKEEEFKLEEEDISFLRAFCAKTYLRLIFNNGQAALILDVDGIPDNETEVERMERMDEVSRAIDFYTNV
EVDKFEEEDYDDEEEEEEYSDEEGNHHSRPKGKIYSQKFVDWKNDYYEQKFGFNLEENKDKITDICENYLEGLQWVLFYY
YRGCPSWSWYFRYHYAPKISDIKLAINKKITFDLGTPYHPFEQLMAVLPSKSKNLVPPGLQPLMLDENSPIIDFYPKTFE
LDMNGKRASWEAVVKIPFVDQDRLLKAIHEREAYLTPEERKRNTFGTDLIFLFNPQVDSVYPSSLPGVFAEVEHDHTIEQ
IYNEPVLPESSYKYGLCDGAKLGVNSLAGFPSLKTLPFSFNFEKAEVKIFERPSRRESLILSIRNQYEDSDSFAISKQFL
GRTVYVGWPYLRQATVVAVSDDMLKYTLDHGKIAQEPHQHLNDWQNDSRNIEMVYKRQGVKVGKTSLLIHVLPLAGMKKL
PSGASVRQFETDMSKEVKLPLQVIVESVQNEDERFIEKPSLPVEEEYPIGSKVVSLLSIAYGTPVTVVGHDNGKLNVDLI
KLDKPESKFGHFIRQREMSGLNYQPAFRFANHLGISPYFCSRITTRYMVSVNGKNYDIGINLRSENRRLKALGYTRKTNA
GWEYSTLAVNLIHEYVTSFSDVLIPLMNSNVKTIPDLSTILGVDSKTASGKIEKMRSWLSSHVTNNVEITLVPFETEGFG
AGACHDLETEIIKRQSTPPSYKVFTLKHVPRQALFSPSSPSYVLSSQKFNLGDRVVSIIDYGKVPLYSRGTVVAIKSFVS
HVTLDIVFDYEMDSGNRLNGNLTTKRGLTVESGAVLNLSNPQLAVSHSSQLKNPKSSGQYAVKKPSAPKPRSANGVVLKK
VTPPVFNKKPASKSSDKPVDAPKKTDQPKPKILTKNKAKSEPSPSKPKKEDKKDAKEAKSGDSLDTMNNDLSKELLSILH
NSKPSDNSVSINPVKSTKNQTANQKKVRSAVINQLTQQQPPQHPPIPPMMQQGPGMMMYPPPFPPNAFPPGPGGPMPYPF
PPPNNGQYNMPPQPPFIPNFNGNPNFMMPGNNFYPPPPSGPMAQPPKNAGEGQGSKFQGKIPTQPKGSGNNESSRGNRNG
KQRGGHRGGRGGRGGNKGKGGSEQKTKE

GO term prediction

Biological Process

GO:0000956 nuclear-transcribed mRNA catabolic process

Molecular Function

GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0008409 5'-3' exonuclease activity

Cellular Component

None predicted.