Protein
MCA_04424_1
Length
1,548 amino acids
Gene name: XRN1
Description: 5'-3' exoribonuclease 1
Browser: contigC:3011397-3016273+
RNA-seq: read pairs 3582, FPKM 28.6, percentile rank 51.3% (100% = highest expression)
Protein function
Annotation: | XRN1 | 5'-3' exoribonuclease 1 | |
---|---|---|---|
KEGG: | K12618 | XRN1 | 5'-3' exoribonuclease 1 [EC:3.1.13.-] |
EGGNOG: | 0PGRH | FGSG_06799 | 5'-3' exoribonuclease |
SGD closest match: | S000003141 | XRN1 | 5'-3' exoribonuclease 1 |
CGD closest match: | CAL0000192354 | KEM1 | 5'-3' exoribonuclease 1 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_03918_1 | 56.85% | 1386 | 0.0 | MIA_03918_1 |
A0A060TFW6_BLAAD | 51.03% | 1313 | 0.0 | 5'-3' exoribonuclease 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26334g PE=3 SV=1 |
A0A0J9YH98_GEOCN | 51.73% | 1272 | 0.0 | 5'-3' exoribonuclease 1 OS=Geotrichum candidum GN=BN980_GECA01s01286g PE=3 SV=1 |
UniRef50_A0A0J9YH98 | 51.73% | 1272 | 0.0 | 5'-3' exoribonuclease 1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9YH98_GEOCN |
A0A167CV40_9ASCO | 48.67% | 1204 | 0.0 | 5'-3' exoribonuclease 1 OS=Sugiyamaella lignohabitans GN=XRN1 PE=3 SV=1 |
Q6CAZ5_YARLI | 44.21% | 1321 | 0.0 | 5'-3' exoribonuclease 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23144g PE=3 SV=1 |
A0A1D8PFP3_CANAL | 44.38% | 1289 | 0.0 | 5'-3' exoribonuclease 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KEM1 PE=3 SV=1 |
XRN1_YEAST | 42.43% | 1348 | 0.0 | 5'-3' exoribonuclease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=XRN1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1899
Protein family membership
- 5'-3' exoribonuclease 1 (IPR016494)
Domains and repeats
-
Domain
-
Domain
1
200
400
600
800
1000
1200
1400
1548
Detailed signature matches
Protein sequence
>MCA_04424_1 MGMYISERWPLISQLVNDNQIPEFDNLYLDMNSIIHNSTHKNGDATFQITEEEMYAQIFNYIEHLFVLIKPKKLFYMAID GVAPRAKMNQQRARRFKSAQDAEEERKKAVEKGLEIPKDPFDSNAITPGTLFMEKLTAHLKYFIHKKISTDSSWQNVEII LSGHEVPGEGEHKIMAHIRHAKAQPDYPSNLRHCLYGLDADLIMLGLSSHDPHFAILREEVLFTPEAKKPKELSQQNFYL LHISIVREYLELEFEGISEEISFPYDFERILDDFILLNFFVGNDFLPELPSLLINDGALPIVIKTYQEFLRSSDGYLTER GEINFPRLGQWLDQFTDFEHKLFEKQAVDLEWLNEELDLITREERLDAVESHHFTLTPLQKKLLGPISDFASRANSIPKP DPMEDDIPIYTIKEEEFKLEEEDISFLRAFCAKTYLRLIFNNGQAALILDVDGIPDNETEVERMERMDEVSRAIDFYTNV EVDKFEEEDYDDEEEEEEYSDEEGNHHSRPKGKIYSQKFVDWKNDYYEQKFGFNLEENKDKITDICENYLEGLQWVLFYY YRGCPSWSWYFRYHYAPKISDIKLAINKKITFDLGTPYHPFEQLMAVLPSKSKNLVPPGLQPLMLDENSPIIDFYPKTFE LDMNGKRASWEAVVKIPFVDQDRLLKAIHEREAYLTPEERKRNTFGTDLIFLFNPQVDSVYPSSLPGVFAEVEHDHTIEQ IYNEPVLPESSYKYGLCDGAKLGVNSLAGFPSLKTLPFSFNFEKAEVKIFERPSRRESLILSIRNQYEDSDSFAISKQFL GRTVYVGWPYLRQATVVAVSDDMLKYTLDHGKIAQEPHQHLNDWQNDSRNIEMVYKRQGVKVGKTSLLIHVLPLAGMKKL PSGASVRQFETDMSKEVKLPLQVIVESVQNEDERFIEKPSLPVEEEYPIGSKVVSLLSIAYGTPVTVVGHDNGKLNVDLI KLDKPESKFGHFIRQREMSGLNYQPAFRFANHLGISPYFCSRITTRYMVSVNGKNYDIGINLRSENRRLKALGYTRKTNA GWEYSTLAVNLIHEYVTSFSDVLIPLMNSNVKTIPDLSTILGVDSKTASGKIEKMRSWLSSHVTNNVEITLVPFETEGFG AGACHDLETEIIKRQSTPPSYKVFTLKHVPRQALFSPSSPSYVLSSQKFNLGDRVVSIIDYGKVPLYSRGTVVAIKSFVS HVTLDIVFDYEMDSGNRLNGNLTTKRGLTVESGAVLNLSNPQLAVSHSSQLKNPKSSGQYAVKKPSAPKPRSANGVVLKK VTPPVFNKKPASKSSDKPVDAPKKTDQPKPKILTKNKAKSEPSPSKPKKEDKKDAKEAKSGDSLDTMNNDLSKELLSILH NSKPSDNSVSINPVKSTKNQTANQKKVRSAVINQLTQQQPPQHPPIPPMMQQGPGMMMYPPPFPPNAFPPGPGGPMPYPF PPPNNGQYNMPPQPPFIPNFNGNPNFMMPGNNFYPPPPSGPMAQPPKNAGEGQGSKFQGKIPTQPKGSGNNESSRGNRNG KQRGGHRGGRGGRGGNKGKGGSEQKTKE
GO term prediction
Biological Process
GO:0000956 nuclear-transcribed mRNA catabolic process
Molecular Function
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0008409 5'-3' exonuclease activity
Cellular Component
None predicted.