Protein
MCA_04396_1
Length
420 amino acids
Gene name: POX1B
Description: Acyl-coenzyme A oxidase
Browser: contigC:2880229-2881492+
RNA-seq: read pairs 197, FPKM 5.8, percentile rank 18.8% (100% = highest expression)
Protein function
| Annotation: | POX1B | Acyl-coenzyme A oxidase | |
|---|---|---|---|
| KEGG: | K00253 | IVD | isovaleryl-CoA dehydrogenase [EC:1.3.8.4] |
| EGGNOG: | 0PFKB | FG08510.1 | Isovaleryl-CoA dehydrogenase |
| SGD closest match: | S000003173 | POX1 | Acyl-coenzyme A oxidase |
| CGD closest match: | CAL0000201368 | POX1 | Acyl-coenzyme A oxidase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04550_1 | 83.14% | 421 | 0.0 | MIA_04550_1 |
| A0A0J9X7D3_GEOCN | 75.71% | 420 | 0.0 | Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s04278g PE=3 SV=1 |
| A0A161HF38_9ASCO | 77.98% | 377 | 0.0 | Isovaleryl-CoA dehydrogenase, mitochondrial OS=Sugiyamaella lignohabitans GN=AWJ20_3827 PE=3 SV=1 |
| A0A060TC96_BLAAD | 75.77% | 392 | 0.0 | ARAD1D37884p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37884g PE=3 SV=1 |
| Q6C643_YARLI | 65.80% | 421 | 0.0 | YALI0E12573p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12573g PE=3 SV=1 |
| A0A1E4TKC4_9ASCO | 63.88% | 418 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30444 PE=3 SV=1 |
| UniRef50_A0A0L1HX35 | 61.61% | 422 | 1e-175 | Isovaleryl-CoA dehydrogenase n=3 Tax=leotiomyceta TaxID=716546 RepID=A0A0L1HX35_9PLEO |
| A0A1E3PQ09_9ASCO | 31.78% | 428 | 1e-67 | Acyl-CoA dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45192 PE=3 SV=1 |
| A0A1D8PQ67_CANAL | 28.42% | 183 | 9e-08 | Acyl-coenzyme A oxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=POX1 PE=3 SV=1 |
| ACOX_YEAST | 27.03% | 148 | 2e-06 | Acyl-coenzyme A oxidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POX1 PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9893
Predicted cleavage: 36
Protein family membership
- Isovaleryl-CoA dehydrogenase (IPR034183)
Domains and repeats
-
Domain
-
Domain
1
50
100
150
200
250
300
350
420
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
substrate binding ...
-
FAD binding site c...
-
catalytic base cd0...
Protein sequence
>MCA_04396_1 MIRSFIRPTLRFSKNQINSTSLKLANTLPLRSRSYATATAEEVEELRQATVEFCKAEISPEVAEKTDVSNQFPNELWKKM GDAGLLGITASEEYGGLKAGYLAHLVVMEEISRASGSIGLSYVAHSNLCINQLSRYVTPEQGAKYLPDLISGRKIGALAM SEAGAGSDVVSMKLTATETEDKSGYILNGTKLWITNGPDADTLVVYAKTDPTKGPKGITTFIIEKDMPGFSVSRKLDKLG MRGSNTGELVFDNVFVPKENILGEINRGVYVLMSGLDYERLLLCGGPIGLMRAALDYTLPYVHQRKQFGVPIAHFQLIQG RLADMYSKMAASRAYSYESARAADAGTLTSMDSAAALLYSAERATEVCLDAIQCLGGMGYVNETPVGRFMRDAKLYEIGG GTSEVRRMVIGRAFNKEYAE
GO term prediction
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Cellular Component
None predicted.