Protein

MCA_04389_1

Length
802 amino acids

Gene name: SEC18

Description: Vesicular-fusion protein SEC18; AAA ATPase and SNARE disassembly chaperone

Browser: contigC:2860567-2863076+

RNA-seq: read pairs 5137, FPKM 79.0, percentile rank 75.1% (100% = highest expression)

Protein function

Annotation:SEC18Vesicular-fusion protein SEC18; AAA ATPase and SNARE disassembly chaperone
KEGG:K06027NSF vesicle-fusing ATPase [EC:3.6.4.6]
EGGNOG:0PIAGSEC18Vesicular-fusion protein sec18
SGD closest match:S000000284SEC18Vesicular-fusion protein SEC18
CGD closest match:CAL0000188106SEC18AAA family ATPase

Protein alignments

%idAln lengthE-value
MIA_01176_177.06%7410.0MIA_01176_1
A0A060T7S1_BLAAD67.62%7380.0ARAD1B22198p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22198g PE=4 SV=1
A0A0J9XC05_GEOCN64.39%7330.0Similar to Saccharomyces cerevisiae YBR080C SEC18 ATPase required for vesicular transport between ER and Golgi OS=Geotrichum candidum GN=BN980_GECA08s03717g PE=4 SV=1
A0A167FBF1_9ASCO61.31%7470.0AAA family ATPase SEC18 OS=Sugiyamaella lignohabitans GN=SEC18 PE=4 SV=1
A0A1E3PGA8_9ASCO56.09%7310.0AAA-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52736 PE=4 SV=1
Q6C470_YARLI56.59%7280.0YALI0E29249p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E29249g PE=4 SV=1
UniRef50_W1QDK353.85%7280.0Vesicular-fusion protein SEC18 n=9 Tax=Saccharomycetales TaxID=4892 RepID=W1QDK3_OGAPD
SEC18_YEAST54.86%7200.0Vesicular-fusion protein SEC18 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC18 PE=1 SV=2
A0A1E4TCT8_9ASCO50.21%7170.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32776 PE=4 SV=1
A0A1D8PFN6_CANAL46.80%7500.0AAA family ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEC18 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0116
Predicted cleavage: 58

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 802

Detailed signature matches

  1. Domain IPR009010
    Aspartate decarboxylase-like domain
    1. SSF50692 (ADC-like)
  2. Domain IPR029067
    CDC48 domain 2-like
    1. G3DSA:3.10.33...
    2. SSF54585 (Cdc48 dom...)
  3. Domain IPR004201
    CDC48, domain 2
    1. PF02933 (CDC48_2)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  6. Domain IPR003959
    ATPase, AAA-type, core
    1. PF00004 (AAA)
  7. SITE IPR003960
    ATPase, AAA-type, conserved site
    1. PS00674 (AAA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.8.60
  2. G3DSA:2.40.40.20
  3. G3DSA:3.40.50...
  4. cd00009 (AAA)
  5. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...
  5. Walker A motif cd0...
  6. ATP binding site c...
  7. Walker B motif cd0...
  8. arginine finger cd...

Protein sequence

>MCA_04389_1
MNFFGGKSTNNPYAQQPDNSGVPPYPTPPPRGGQPTPQYYSQSNSPQPYQSSTPPRIKSSRYSIVNAPDSTYVISNHAAV
PVGSFQDGEYIIVDGKYVFTAQTSPAIQPTEIGLGQISREWGSWSLRQEVDIQPFDIFKTGQGRVYLGTLQVEIDFLNKS
KASDHQYDQGDLGKRFLQLFKTQIFAPGQKLVMEYKGLNFRVKVINTSVVDLGKGSDPSSTAGARGILVDQTQIDFLKPK
GGLINLKVSGDRPRANAILQPNFKFEDMGIGGLDDEFSTIFRRAFASRIYPPRDIEKLGIKHVKGMLLYGPPGTGKTLIA
RQIGKMLNAREPKIVNGPEMLNKFVGGSEENIRKLFKDAETEYREKGDESSLHIIIFDELDAVFKQRGSRGDGTGVGDNV
VNQLLAKMDGVDQLNNILVIGMTNRKDLIDSALLRPGRFEVQLEISLPDESGRKQIFKIHTSRMAKEGMLNKDVNIDELA
SKTKNYSGAEIEGLVKSAASFALNRNIKFDPKKGISFNNKAVKVCRDDFVRALDETKPAFGVSEDELEKFLRGGIIKYTP
RINEILAEGSAIIGASQSDQFPLTSVLIHGPAKAGKSALAASIALSSGFPFIRMISSRAMVGMNEQNRIQYISNMFNDSY
KSTHNVIVIDQIEDIIEWVNVGPRFSNGVLHCLKTFLATLPPENRRLVVLVTTRHREILEQLDLISAFNKQIYVSNVRTL
AELNTIFQEVSFLSDSDKKEAIKQIQDQTGSTTLSMGIKDILFNIESARLSKRSELEEFVRLTVNDISMQPGRQITGGFQ
FS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding

Cellular Component

None predicted.