Protein
MCA_04388_1
Length
935 amino acids
Gene name: LHS1
Description: protein of the HSP70 family; molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding
Browser: contigC:2857529-2860337+
RNA-seq: read pairs 2397, FPKM 31.6, percentile rank 54.2% (100% = highest expression)
Protein function
| Annotation: | LHS1 | protein of the HSP70 family; molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding | |
|---|---|---|---|
| KEGG: | K09486 | HYOU1 | hypoxia up-regulated 1 |
| EGGNOG: | 0PFF0 | LHS1 | Heat shock protein |
| SGD closest match: | S000001556 | LHS1 | Heat shock protein 70 homolog LHS1 |
| CGD closest match: | CAL0000184682 | LHS1 | Hsp70 family chaperone |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00009_1 | 40.76% | 844 | 2e-174 | MIA_00009_1 |
| A0A0J9XBZ4_GEOCN | 37.26% | 722 | 1e-132 | Similar to Saccharomyces cerevisiae YKL073W LHS1 Molecular chaperone of the endoplasmic reticulum lumen OS=Geotrichum candidum GN=BN980_GECA08s04938g PE=3 SV=1 |
| UniRef50_A0A0J9XBZ4 | 37.26% | 722 | 3e-129 | Similar to Saccharomyces cerevisiae YKL073W LHS1 Molecular chaperone of the endoplasmic reticulum lumen n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBZ4_GEOCN |
| A0A161HLU7_9ASCO | 33.42% | 760 | 2e-122 | Hsp70 family chaperone LHS1 OS=Sugiyamaella lignohabitans GN=LHS1 PE=3 SV=1 |
| A0A060T5Y2_BLAAD | 34.35% | 754 | 4e-112 | ARAD1B15268p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B15268g PE=3 SV=1 |
| A0A1E3PEP5_9ASCO | 39.82% | 452 | 5e-99 | Actin-like ATPase domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27633 PE=3 SV=1 |
| Q6CFA8_YARLI | 31.13% | 742 | 3e-90 | YALI0B08778p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08778g PE=3 SV=1 |
| LHS1_YEAST | 29.82% | 778 | 3e-86 | Heat shock protein 70 homolog LHS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LHS1 PE=1 SV=1 |
| A0A1D8PGU0_CANAL | 27.43% | 773 | 2e-68 | Hsp70 family chaperone OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LHS1 PE=3 SV=1 |
| A0A1E4TAL7_9ASCO | 31.90% | 348 | 2e-42 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32260 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2580
Protein family membership
- Heat shock protein 70 family (IPR013126)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
800
935
Detailed signature matches
-
-
PF00012 (HSP70)
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no IPR
Unintegrated signatures
-
-
-
NON_CYTOPLASM... (N...)
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PS51257 (PROKAR_LIP...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SSF53067 (Actin-lik...)
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-
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mobidb-lite (disord...)
Protein sequence
>MCA_04388_1 MRLLNFKHLISLFLVLLISIACQAVILGIDLGESYSKSFLLAPGLPFEPVLSSDSKRKDLSAITFKITPAPGSSKSTTIE RIYGNSAQAFFVRHPKNSLFYFKPLLGANSAESSISGNTKTKNVGPIDEYLSMFRGIDLVPSKNNRSTVAVSLPSISDDL EKEEYPIEEVVAMYLADIKYRANNIVSSFRQAKAGTNAMSILSGDVSSVAVTTPPHFNMAQRSALKDAIELAGLQLVSFV NDGVSVITNYVSNRQFSSDKPEYHLVYDLGAGSISAALFSVVGSNDNSVIVNVENVAFDENFGGNKLTDIVRSELIDKLV TQHPSLKRDTVVNDPKVMRKLWIESERVKNILSANNQVNSHVESLYEDLDFRATFTRQEFEKLMESKNFVKRALDPIFKA FSTSSMLNKDSQFKNYKTQLNSIIYMGGTTRIPSIQKAISSSFGEDLISKQVNTDEAAALGATLRGVGISRIFKTRNITV VDRSLNEYSATVGKSDLPLFKRGDLANTQNEIIIPYNKKLLSKNGDLTIPIKENGKDIMLLDIKQVEQTLSDQKCSTNDA LVKVKFFYSFSHMLEIEDLYIECKSTEPKTESDVKADSTKRVSIAKKIRYPGPRPMGSVSKQNSSQRIAKFDKMDKERQQ HDILRNKLEGEIYKIKEYYYTIQDTQEEGNGEVIIPEDLLNNLGQQVEQLMEWLEYESQDSSIEDMKNKRKSVEALRKRI NRILNPKEEEERIASTANLFKSNLEQLTRSNAQHKEEHKTQVQKLLSHFTATFLKPEDIQKEKNQETPVVRATPEQEVIL KTPEAQEIFKLLQQEPDVSPEEEAQMSSLLEKGAELIEKLKPSQDSNQQKKQQVITPQEEEQKYEEREQLIHDIKATLGK FADMEKKIQSKRFDTIRKVKKLIKDLKKQFQPSESTSPETASAQPSSTEKIKEDL
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.