Protein

MCA_04346_1

Length
596 amino acids

Gene name: CNA1

Browser: contigC:2761950-2763741-

RNA-seq: read pairs 5520, FPKM 114.2, percentile rank 80.9% (100% = highest expression)

Protein function

Annotation:CNA1
KEGG:K04348PPP3C serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
EGGNOG:0PGAUCNA1serine threonine-protein phosphatase
SGD closest match:S000004425CNA1Serine/threonine-protein phosphatase 2B catalytic subunit A1
CGD closest match:CAL0000201614CMP1Serine/threonine-protein phosphatase

Protein alignments

%idAln lengthE-value
MIA_01980_173.48%5920.0MIA_01980_1
A0A0J9XD65_GEOCN69.75%6050.0Serine/threonine-protein phosphatase OS=Geotrichum candidum GN=BN980_GECA10s01462g PE=3 SV=1
A0A060TDD8_BLAAD68.15%5840.0Serine/threonine-protein phosphatase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D05654g PE=3 SV=1
A0A1E3PGD2_9ASCO65.59%5900.0Serine/threonine-protein phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52764 PE=3 SV=1
UniRef50_K1XF4363.20%5870.0Serine/threonine-protein phosphatase n=17 Tax=Fungi TaxID=4751 RepID=K1XF43_MARBU
Q6C5D3_YARLI63.93%5850.0Serine/threonine-protein phosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E19008g PE=3 SV=1
A0A1E4TJI5_9ASCO54.77%5970.0Serine/threonine-protein phosphatase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30199 PE=3 SV=1
A0A1D8PCA8_CANAL57.64%5500.0Serine/threonine-protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CMP1 PE=3 SV=1
A0A167BZC0_9ASCO72.64%4130.0Serine/threonine-protein phosphatase OS=Sugiyamaella lignohabitans GN=CMP2 PE=3 SV=1
PP2B1_YEAST54.17%5150.0Serine/threonine-protein phosphatase 2B catalytic subunit A1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CNA1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0739

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 596

Detailed signature matches

  1. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  2. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  3. Domain IPR006186
    Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
    1. PS00125 (SER_THR_PH...)
    2. SM00156 (pp2a_7)
    3. PR00114 (STPHPHTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd07416 (MPP_PP2B)
  3. mobidb-lite (disord...)

Residue annotation

  1. CN-CyPA-CsA comple...
  2. metal binding site...
  3. active site cd07416

Protein sequence

>MCA_04346_1
MSKDNSDNMAAQNSIQLENAIRAFKEKKPIPKTDLTTYTTEDGTTTSTVERAIKKVRAPAWSKPTDDEFFDKTDPTKPNL
KFLKNHLYCEGRLSDEHALYIINSATQILRSEPTLLEVEAPVTVCGDVHGQYYDLMKLFEVGGDPATTRYLFLGDYVDRG
YFSIECVLYLWALKMWYPNSIFLLRGNHECRHLTEYFTFKLECQHKYNTKIYDACMASFCTLPLAAVMNKQFLCVHGGLS
PELRSLDDIRKLDRFREPPTRGLMCDLLWSDPAEDFGKETTSDRYTVNSVRGCSYFYTYAAACEFLERTGLLSIIRAHEA
QDAGYRTYRKTRVNGFPSLMTIFSAPNYLDTYGNKAAVLKYEDNIMNIRQFNSSPHPYWLPNFMDVFTWSLPFVGEKITD
MLIAILNICTKEELEEETVLDLNNSTIRSAVTDAREPFVVPSLDQSSSTTSGSTSPGVITPLDRSGSTGGSDEFGDDTTI
EERRSAMKNKIMAIGRMSRLFRVLRQEAESLSELKAHTGGKLPSGTLFLGTEGIRQAISTFEEARRADIINEALPPTHEE
AAAKEEQARKDQLQKALNEADSDVSMQRLARRLSMG

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.