Protein

MCA_04317_1

Length
684 amino acids

Gene name: CIR2

Description: Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

Browser: contigC:2690829-2692884-

RNA-seq: read pairs 3952, FPKM 71.3, percentile rank 73.1% (100% = highest expression)

Protein function

Annotation:CIR2Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
KEGG:K00311ETFDH electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]
EGGNOG:0PFF4PGUG_03378electron transfer flavoprotein-ubiquinone oxidoreductase
SGD closest match:S000005883CIR2Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
CGD closest match:CAL0000188515orf19.3175Putative electron-transferring-flavoprotein dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_00116_175.18%6850.0MIA_00116_1
A0A0J9XKE8_GEOCN71.13%6720.0Similar to Saccharomyces cerevisiae YOR356W CIR2 Putative ortholog of human electron transfer flavoprotein dehydrogenase (ETF-dH) OS=Geotrichum candidum GN=BN980_GECA24s00747g PE=4 SV=1
A0A060SWP5_BLAAD73.15%5960.0ARAD1A02684p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02684g PE=4 SV=1
A0A167EV65_9ASCO63.66%6880.0Cir2p OS=Sugiyamaella lignohabitans GN=CIR2 PE=4 SV=1
A0A1E3PJ54_9ASCO66.51%6270.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46765 PE=4 SV=1
Q6CBW8_YARLI61.31%6540.0YALI0C14806p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C14806g PE=4 SV=1
A0A1E4TH99_9ASCO65.73%6040.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2830 PE=4 SV=1
A0A1D8PNB3_CANAL57.92%6440.0Putative electron-transferring-flavoprotein dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3175 PE=4 SV=1
UniRef50_B9WHC360.16%6100.0Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, putative n=19 Tax=Ascomycota TaxID=4890 RepID=B9WHC3_CANDC
ETFD_YEAST58.87%6200.0Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CIR2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9977
Predicted cleavage: 85

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 684

Detailed signature matches

  1. Domain IPR023753
    FAD/NAD(P)-binding domain
    1. G3DSA:3.50.50.60
    2. SSF51905 (FAD/NAD(P...)
  2. Domain IPR017896
    4Fe-4S ferredoxin-type, iron-sulphur binding domain
    1. PS51379 (4FE4S_FER_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. PF05187 (ETF_QO)
  3. PF13450 (NAD_binding_8)
  4. SSF54373 (FAD-linke...)
  5. SSF54862 (4Fe-4S fe...)

Protein sequence

>MCA_04317_1
MIRHSKSTGAARSLLSKTLINSELRVAVPRLAQSTKQTSLPSHSQPIIQSTRKLSTLRTSNVNKRIIAPRSISVRSFASI
ADATPEQKENLDPALSEPREADEVDVAIVGGGPAGLAAAIKLKQLDNEHGSGELRVIVLEKAPDMGAHTLSGAVLEPRAL
DELIPDWREDPPAPLTMVKSEAMKFLTKSMAVPIPEPPQMHNKGKNYIVSLNQVVKWMAEKAEELGVEIYPGFSVSEVVY
DEETGAVKGIATNDMGVSKDFTPKDNFQRGMEFHAKVTLFAEGCHGSLTKEVIKKFDLRANSDPQTYGIGIKEVWEVPED
VWNEGFVAHTMGYPLSYDTYGGGFMYHFGERLVSVGLVVGLDYANPWLSPYQEFQNLKRHPFYKKVLEKGKCISYGARAL
NEGGLQSIPKLIFPGGALIGCTAGFLNVPKIKGTHTAMKSGMLAAEAAFNSIQEQLKLTEDEEAELEESENLEETDEEAI
EAEEETRQFPPIVLQEYETSIEKSWVYEELKEVRNVRPSFNTKLGLWGGIAWSGLDTLLLKGRTPFTFHNKVTDALHTKP
ADQFKKIEYPIKPDNKLTFDLLTSVSRTGTMHDDDEPCHLRVPNQDLKEHAKKSYPKFKGVEQRFCPAGVYEYIPDETDK
ELGVRFQINSQNCIHCKTCDIKVPTQDINWTTPEGGDGPKYYMT

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.