Protein

MCA_04314_1

Length
475 amino acids


Gene name: NPY1

Description: NADH pyrophosphatase

Browser: contigC:2678731-2680159+

RNA-seq: read pairs 1141, FPKM 29.6, percentile rank 52.4% (100% = highest expression)

Protein function

Annotation:NPY1NADH pyrophosphatase
KEGG:K03426E3.6.1.22 NAD+ diphosphatase [EC:3.6.1.22]
EGGNOG:0PGJ2NPY1NADH pyrophosphatase
SGD closest match:S000003035NPY1NADH pyrophosphatase
CGD closest match:CAL0000197881orf19.3482NAD(+) diphosphatase

Protein alignments

%idAln lengthE-value
MIA_01976_151.81%4691e-164MIA_01976_1
A0A0J9XFS5_GEOCN46.96%4774e-139Similar to Saccharomyces cerevisiae YGL067W NPY1 NADH diphosphatase (Pyrophosphatase) OS=Geotrichum candidum GN=BN980_GECA14s00598g PE=4 SV=1
A0A167CLA2_9ASCO40.04%4676e-107NAD(+) diphosphatase OS=Sugiyamaella lignohabitans GN=NPY1 PE=4 SV=1
UniRef50_A0A167CLA240.04%4672e-103NAD(+) diphosphatase n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CLA2_9ASCO
A0A060TAZ8_BLAAD39.83%4622e-105ARAD1D24068p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D24068g PE=4 SV=1
Q6C2F8_YARLI38.60%4568e-100YALI0F08283p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F08283g PE=4 SV=1
A0A1E3PLR6_9ASCO38.39%5081e-98Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82220 PE=4 SV=1
A0A1E4TLZ0_9ASCO37.55%4582e-95Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30817 PE=4 SV=1
A0A1D8PPW7_CANAL30.38%4741e-58NAD(+) diphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3482 PE=4 SV=1
NPY1_YEAST30.24%4533e-48NADH pyrophosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPY1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0393

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 475

Detailed signature matches

    1. SSF55811 (Nudix)
    1. PF09297 (zf-NADH-PPase)
    1. PS51462 (NUDIX)
    2. PF00293 (NUDIX)
    1. PS00893 (NUDIX_BOX)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd03429 (NADH_pyrop...)

Residue annotation

  1. putative NADH bind...
  2. nudix motif cd03429
  3. putative active si...
  4. putative metal bin...

Protein sequence

>MCA_04314_1
MSLVSFLGHEPINYYGKSSLNRLSFLRDNYNFLHQAISHPSTKFLILEELTPPTIDTGYKDSVSEDNNVITTDPNDKSAP
PFKDRPALQKLVYFDYSTIKDLLTVEPFKLDEQKQIENWDSEKDSIGIEKPLIVFLGLKEFSNLSPFANLDDNNEKVKEP
ENVFTFSSNNNNKTEFKGIPYFAIDISSSYIKPDSPLQSSVSKLRAKIPELQKLHETVTKNSRFNPFGLRLSAVESTIFG
QARHYADWNLRNRFCGGCGQPTMSVNGGCKLTCPPTNKSLPQPPCPTRGAITNLHFPRTDVSIISIVLNHDGSKVLLGRG
KRFPDKFYSCLAGFLEPAETIEDCVRREIWEEAGIHVDRVLMYSSQPWPFPANIMIGCVSQVYTRPSSSSSSNDEKDDEI
DLGNDPELADAKWFDIEELRKSSLKYAPLGTFAYRPEQLLDHQPQIPPPEAVAWTLIDAVCNGRIKGLKSMATKI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity
GO:0046872 metal ion binding

Cellular Component

None predicted.