Protein

MCA_04283_1

Length
667 amino acids

Gene name: SOK2

Description: Enhanced filamentous growth protein 1; in S. cerevisiae negatively regulates pseudohyphal differentiation; plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway

Browser: contigC:2586737-2588741-

RNA-seq: read pairs 3918, FPKM 72.5, percentile rank 73.4% (100% = highest expression)

Protein function

Annotation:SOK2Enhanced filamentous growth protein 1; in S. cerevisiae negatively regulates pseudohyphal differentiation; plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway
KEGG:K12763EFG1 enhanced filamentous growth protein 1
EGGNOG:0PIW3FG10129.1cell pattern formation-associated protein
SGD closest match:S000004618SOK2Protein SOK2
CGD closest match:CAL0000201973EFG1Enhanced filamentous growth protein 1

Protein alignments

%idAln lengthE-value
A0A0J9XDK1_GEOCN70.35%1991e-78Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA11s01176g PE=4 SV=1
UniRef50_A0A0J9XDK170.35%1992e-75Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDK1_GEOCN
A0A060T7Q3_BLAAD84.14%1451e-74ARAD1D01430p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D01430g PE=4 SV=1
A0A161HJ79_9ASCO83.33%1441e-73Sok2p OS=Sugiyamaella lignohabitans GN=SOK2 PE=4 SV=1
Q6CAM0_YARLI77.18%1492e-67YALI0D01573p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D01573g PE=4 SV=1
MIA_05175_178.15%1195e-62MIA_05175_1
A0A1E3PE71_9ASCO87.25%1025e-61Apses-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_11155 PE=4 SV=1
SOK2_YEAST64.62%1304e-47Protein SOK2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SOK2 PE=1 SV=1
EFG1_CANAL73.74%993e-47Enhanced filamentous growth protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EFG1 PE=1 SV=2
A0A1E4TFZ8_9ASCO47.96%982e-25Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31576 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0000

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 667

Detailed signature matches

  1. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  2. Domain IPR003163
    Transcription regulator HTH, APSES-type DNA-binding domain
    1. PS51299 (HTH_APSES)
    2. G3DSA:3.10.26...
    3. SSF54616 (DNA-bindi...)
  3. Domain IPR018004
    KilA, N-terminal/APSES-type HTH, DNA-binding
    1. SM01252 (KilA_N_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_04283_1
MSYQQAPYYTYPSQNYVQQQQQPAQQASSPTVMTPTATTTTTTTASSYPVSAPTTASTTPLPDQQQQQQQQQQPQQTPQS
YYYSPMYYSQQQQQQQQQPQPQQPQQQQQPQPQTNQQQQTQTTLPHPSQPSSHTNTPTQTPTTLPPPINQQGYYSSSANS
LYYSNVAQQDVNYPNPSPVHTAAATPSPTAATSATATPTSATIPSQYPYSQFPPQFQTPSSNAYLANPYAMGALAPASSI
AMAGGQFPYPYSLHQAQQFQFQQQQQQQFYQQQYHSGYPPQPIIATITDPTGQKPPPNIKPKITTTLWEDEGTLCFQVEA
RGISVARREDNNMINGTKLLNVAGMTRGRRDGILKGEKSRHVVKAGAMHLKGVWIPYERALDFANREKIIDLLYPLFVND
LKALLYHPANLERTQQVISAAEKRKAEVLKMEENKQKKELEEQGKTEPCSPNNNPEIKQEDDKSKVSSSPSNRYSLEQIC
DNTNNTNPSTNNTTTSASNTSSTSQPATASNTSSPSLYNNNNNNTNNNNNNNEPSIYQQKPYDNRVGEYQQTSYSNNNFH
HPPPISTSVPTYTMNSGTPTPVSANLPLISPSSAHYNNNKGNQFSNQYQPQQQQQQYALPPVAPSMVSQQQQQTPPPSAS
LESGNGDVSNGLLPPPSRIATGIPPSS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003677 DNA binding
GO:0005515 protein binding

Cellular Component

None predicted.