Protein

MCA_04271_1

Length
558 amino acids

Gene name: LCB1

Description: Serine palmitoyltransferase 1

Browser: contigC:2556397-2558074-

RNA-seq: read pairs 9048, FPKM 200.0, percentile rank 88.0% (100% = highest expression)

Protein function

Annotation:LCB1Serine palmitoyltransferase 1
KEGG:K00654SPT serine palmitoyltransferase [EC:2.3.1.50]
EGGNOG:0PGFCLCB1serine palmitoyltransferase
SGD closest match:S000004911LCB1Serine palmitoyltransferase 1
CGD closest match:CAL0000192873CAALFM_CR08640CASerine C-palmitoyltransferase

Protein alignments

%idAln lengthE-value
MIA_02294_158.58%5650.0MIA_02294_1
A0A0J9X546_GEOCN53.12%5610.0Similar to Saccharomyces cerevisiae YMR296C LCB1 Component of serine palmitoyltransferase OS=Geotrichum candidum GN=BN980_GECA02s07886g PE=4 SV=1
UniRef50_A0A0J9X54653.12%5610.0Similar to Saccharomyces cerevisiae YMR296C LCB1 Component of serine palmitoyltransferase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X546_GEOCN
A0A167DL08_9ASCO44.26%5498e-168Serine C-palmitoyltransferase LCB1 OS=Sugiyamaella lignohabitans GN=LCB1 PE=4 SV=1
A0A060TF36_BLAAD47.46%5525e-158ARAD1D19910p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D19910g PE=4 SV=1
A0A1E3PKD2_9ASCO43.07%5341e-136PLP-dependent transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24617 PE=4 SV=1
Q5A325_CANAL41.62%5672e-130Serine C-palmitoyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR08640CA PE=4 SV=1
Q6CD74_YARLI37.28%5586e-118YALI0C03179p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C03179g PE=4 SV=1
A0A1E4TL24_9ASCO34.98%6099e-112Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30523 PE=4 SV=1
LCB1_YEAST34.32%5427e-94Serine palmitoyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LCB1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0586

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 558

Detailed signature matches

  1. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  2. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  3. Domain IPR004839
    Aminotransferase, class I/classII
    1. PF00155 (Aminotran_1_2)
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_04271_1
MEKLDRLYQDFGELLSTASETALSKISTIPGSAIVLRYIKSSYQNDPIRSFLEALLVLFAIRYFLASKYSTNKKNFVKLE
DYEIDDLVDEWEPEPLVFPVTESEALTLKSTPVIKGPNGFKVHLTTEDEVLNSSDLLNASLLKTIPTISEDDPVYLNFSN
TDIFYIGGRPFAREEASKIIHAYGVGSCGPAGFYGNQDAHIQCEKDISKFIGTEKTILYSQYFATPSSVIPCFFKRGDYI
IADSNVNITIQKGIVLSRAHIYWFKHNDMEDLEAKVIQATKAHRKGPIPRRVIITEGIFENSGDSPDLKKIVEIRNKYKF
RILLDESWSLGVLGKTGRGLPEQCGVDRKDIDFTIGSLVNGFGSAGGFCAGPRQMVDYQQITSLAYTFSATMPPYLAHNT
SVAITKFLDTEEYRTTELPKLKREIQAFHDELSKTSFSKYARVVSRPDSALIIMRLLSDRIPNFSTESVDEKGVVSFTKT
KSKKLALVEDDNHSLLLQKIVDKARSKGIIIARVQTLGNVAKSQVEQGLRLILSTGFTEDEVRRGARVVSEAIQEVIN

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.