Protein

MCA_04255_1

Length
251 amino acids

Browser: contigC:2506183-2507450+

RNA-seq: read pairs 4536, FPKM 222.4, percentile rank 89.2% (100% = highest expression)

Protein function

KEGG:K07889RAB5C Ras-related protein Rab-5C
EGGNOG:0PFKAPGUG_01959Vacuolar protein sorting-associated protein
SGD closest match:S000005615VPS21Vacuolar protein sorting-associated protein 21
CGD closest match:CAL0000181874VPS21Rab family GTPase

Protein alignments

%idAln lengthE-value
MIA_02200_168.27%2714e-113MIA_02200_1
A0A060T631_BLAAD70.56%2142e-98ARAD1B16170p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B16170g PE=4 SV=1
A0A1E3PID5_9ASCO60.38%2655e-98Putative rab GTPase Vps21/Ypt51 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_25226 PE=4 SV=1
Q6C9Z5_YARLI62.30%2444e-96YALI0D07128p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D07128g PE=4 SV=1
UniRef50_Q6BYB060.25%2444e-88DEHA2A10956p n=39 Tax=Eukaryota TaxID=2759 RepID=Q6BYB0_DEBHA
Q59X89_CANAL60.25%2442e-90Rab family GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPS21 PE=4 SV=1
A0A1E4TC18_9ASCO66.34%2052e-89Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_137154 PE=4 SV=1
VPS21_YEAST59.41%2394e-89Vacuolar protein sorting-associated protein 21 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS21 PE=1 SV=1
A0A0J9X421_GEOCN68.42%2096e-83Similar to Saccharomyces cerevisiae YOR089C YPT51 Rab family GTPase OS=Geotrichum candidum GN=BN980_GECA01s07006g PE=4 SV=1
A0A167F051_9ASCO48.89%2256e-61Rab family GTPase VPS21 OS=Sugiyamaella lignohabitans GN=VPS21 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0354
Predicted cleavage: 35

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 251

Detailed signature matches

  1. Family IPR001806
    Small GTPase superfamily
    1. PF00071 (Ras)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.70...
  2. G3DSA:3.40.50...
  3. PR00449 (RASTRNSFRMNG)
  4. PS51419 (RAB)
  5. SM00173 (ras_sub_4)
  6. SM00174 (rho_sub_3)
  7. SM00175 (rab_sub_5)
  8. SM00176 (ran_sub_2)
  9. cd01860 (Rab5_related)
  10. mobidb-lite (disord...)

Residue annotation

  1. Rab subfamily moti...
  2. G1 box cd01860
  3. GTP/Mg2+ binding s...
  4. Rab subfamily moti...
  5. Switch I region cd...
  6. putative GEF inter...
  7. G2 box cd01860
  8. Rab family motif 1...
  9. putative GDI inter...
  10. effector interacti...
  11. Rab family motif 2...
  12. G3 box cd01860
  13. Switch II region c...
  14. Rab family motif 3...
  15. Rab family motif 4...
  16. Rab family motif 5...
  17. Rab subfamily moti...
  18. G4 box cd01860
  19. G5 box cd01860
  20. Rab subfamily moti...

Protein sequence

>MCA_04255_1
MDPVTPPQPKQTTSVKLVLLGEAAVGKSSLVLRFVSNDFQENKEPTIGAAFLTQKCNLPNRTVKFEIWDTAGQERFASLA
PMYYRNAQSAVIVYDVTKPTSFIKARHWVNELKAQASKNIIIALVGNKVDLIKNSSKSKKNGSSTSVDDDNEGADEDEDD
EDEDGKVTRKVAREEGEALAKSEGLLFFETSAKLGLNVSEVFFSIANKIPEESAKKGGPNGASGPGENGREGRIDLAAGA
NGGAGAQSCSC

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.