Protein

MCA_04235_1

Length
354 amino acids

Gene name: CRD1

Description: Cardiolipin synthase (CMP-forming)

Browser: contigC:2440461-2441526-

RNA-seq: read pairs 1263, FPKM 44.0, percentile rank 62.4% (100% = highest expression)

Protein function

Annotation:CRD1Cardiolipin synthase (CMP-forming)
KEGG:K08744CRLS cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
EGGNOG:0PHWVFGSG_02593synthase
SGD closest match:S000002301CRD1Cardiolipin synthase (CMP-forming)
CGD closest match:CAL0000197186orf19.6100Cardiolipin synthase

Protein alignments

%idAln lengthE-value
MIA_02305_174.79%2383e-126MIA_02305_1
A0A0J9XG37_GEOCN71.89%2173e-106Similar to Saccharomyces cerevisiae YDL142C CRD1 Cardiolipin synthase OS=Geotrichum candidum GN=BN980_GECA14s03200g PE=3 SV=1
A0A060T4K6_BLAAD67.11%2281e-103ARAD1C41426p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41426g PE=3 SV=1
A0A161HH32_9ASCO65.90%2171e-97Cardiolipin synthase OS=Sugiyamaella lignohabitans GN=CRD1 PE=3 SV=1
UniRef50_A0A161HH3265.90%2173e-94Cardiolipin synthase n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A161HH32_9ASCO
A0A1E3PM56_9ASCO68.57%2102e-96CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_6847 PE=3 SV=1
Q6C0K8_YARLI60.71%2246e-90YALI0F23837p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23837g PE=3 SV=1
Q5AB72_CANAL43.40%2127e-52Cardiolipin synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6100 PE=3 SV=1
CRD1_YEAST40.25%2412e-47Cardiolipin synthase (CMP-forming) OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CRD1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9991
Predicted cleavage: 84

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

  1. Family IPR000462
    CDP-alcohol phosphatidyltransferase
    1. PS00379 (CDP_ALCOHO...)
    2. PF01066 (CDP-OH_P_t...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MCA_04235_1
MSWIVPSTTNLLTPIRGTIVSNVSQLLLISRSARRVTTSRSISQLIYNRKGTIKQQNQFKGIFFNNQKISCFNSKNNLCI
RYYSSNPPSSQNTTSNTTTSSSEPPTTNETKKLTKIAKATEQLTKAKNAIRDAKSKLKSTVPSHENIYTLPNFLTVTRLI
SAPIIGYLVVHQQLGWALSLFAYSCVTDFVDGFIARHYKLQTVVGSVIDPMADKFLMMTLASCLAASGDIPMYMAVLILG
RDFLLGLSAFYYRYISLPPPKTFTRYWDFSIPSAEVHPTTISKYNTFFQMIYLGLSLAHPVLNDSIAAGGMEWLAQYSNY
INWGMQGLEYTVATTTILSGLSYVFSKNAVKILK

GO term prediction

Biological Process

GO:0008654 phospholipid biosynthetic process

Molecular Function

GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Cellular Component

GO:0016020 membrane