Protein

MCA_04215_1

Length
717 amino acids

Gene name: RTS1

Description: B-type regulatory subunit of protein phosphatase 2A (PP2A); in S. cerevisiae protects cohesin when recruited by Sgo1p to the pericentromere

Browser: contigC:2374381-2376953+

RNA-seq: read pairs 3965, FPKM 68.2, percentile rank 72.0% (100% = highest expression)

Protein function

Annotation:RTS1B-type regulatory subunit of protein phosphatase 2A (PP2A); in S. cerevisiae protects cohesin when recruited by Sgo1p to the pericentromere
KEGG:K11584PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
EGGNOG:0PFJ3PGUG_04000Serine threonine protein phosphatase 2A
SGD closest match:S000005540RTS1Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
CGD closest match:CAL0000194680RTS1Protein phosphatase 2A regulatory subunit

Protein alignments

%idAln lengthE-value
MIA_02698_180.19%5250.0MIA_02698_1
A0A060T8B9_BLAAD78.62%4770.0ARAD1C35596p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35596g PE=4 SV=1
A0A0J9XKS5_GEOCN74.69%4780.0Similar to Saccharomyces cerevisiae YOR014W RTS1 B-type regulatory subunit of protein phosphatase 2A (PP2A) OS=Geotrichum candidum GN=BN980_GECA32s01759g PE=4 SV=1
A0A1E3PGE5_9ASCO70.48%4810.0Protein phosphatase 2A regulatory B subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47174 PE=4 SV=1
A0A167DEJ8_9ASCO69.77%4830.0Protein phosphatase 2A regulatory subunit RTS1 OS=Sugiyamaella lignohabitans GN=RTS1 PE=4 SV=1
UniRef50_A0A167DEJ869.77%4830.0Protein phosphatase 2A regulatory subunit RTS1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DEJ8_9ASCO
Q6C7K1_YARLI66.39%4820.0YALI0E00154p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00154g PE=4 SV=1
2A5D_YEAST63.07%4630.0Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTS1 PE=1 SV=2
Q59Q44_CANAL70.60%3810.0Protein phosphatase 2A regulatory subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RTS1 PE=4 SV=1
A0A1E4TLY9_9ASCO61.82%4069e-177Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12650 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9409
Predicted cleavage: 13

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 717

Detailed signature matches

  1. Family IPR002554
    Protein phosphatase 2A, regulatory B subunit, B56
    1. PF01603 (B56)
    2. PIRSF028043 (PP2A_B56)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_04215_1
MMKGWTKRLARSKSHSKGKKDNEKKSSSSLRSESSSSSLKGDNREKEIKDRDSSKSSQQQLQHQHSSSKLNQNGKSSTSQ
QQSQNSDPSDPQVQQQQQQQTNPYNQNQSPNGSLNPQPQQQQQSQQQQPYLIYDGNSQMNSFDQNSSNDSNNSSSLNPPF
HHLSPPSLIVSPSVTGHAPPPGSTETMPQDLDSLAFSNNTNGSGPTSPQRLSFERHSIDGIKTPKRHNSSRFEISEKREL
EPLPSLSEVPSAERNELFLKKVDQCAVIFDFNDPSSDMKGKEIKTNALNDLLDYITTNHIQIFDEMYEKVVTMFAKNLFR
PIPPPVNPVGELFDPDEDEPICEVSWPHMQIVYEFFLRFIESSDFNHNIAKRYIDHQFVQNLLELFDSEDPRERDCLKTT
LHRIYGKFLNLRAFIRRSMNNVFFQFMYETERFNGIAELLEILGSIINGFALPLKEEHKIFLSRVLIPLHKVRSLSLYHS
QLAYCIVQFLEKDPTLTEEVIIGLLRYWPKVSSPKEVLFLIEIEDIFEIIDPNEFVKIQIPLFVQLSKCIASPHFQVAER
VLYFWSHEYFCSLVTENSETILPIIFSALHENASSHWNRSIHSMILSATKIFMEANPVLFDHCALLYKQSREAAQRREQI
RQDSWKLLEQQVNNSKGKENNQNNSNNNNSNDENNNNNQQQEEEQQQLTGSKSSSLQSASQMSATNTSMAGQQGILS

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

GO:0005488 binding
GO:0005515 protein binding
GO:0019888 protein phosphatase regulator activity

Cellular Component

GO:0000159 protein phosphatase type 2A complex