MCA_04214_1

Protein

Length

1,591 amino acids

Gene name: MYO2

Description: Myosin-2

Browser: contigC:2367506-2372927+

RNA-seq: read pairs 9811, FPKM 76.1, percentile rank 74.4% (100% = highest expression)

Protein function

Annotation:		MYO2	Myosin-2
KEGG:	K10357	MYO5	myosin V
EGGNOG:	0PI8B	MYO2	class V myosin
SGD closest match:	S000005853	MYO2	Myosin-2
CGD closest match:	CAL0000190717	MYO2	Myosin 2

Protein alignments

	%id	Aln length
MIA_02697_1	76.30%	1540	MIA_02697_1
A0A0J9XEB8_GEOCN	70.34%	1561	Similar to Saccharomyces cerevisiae YOR326W MYO2 Type V myosin motor involved in actin-based transport of cargos OS=Geotrichum candidum GN=BN980_GECA12s03282g PE=3 SV=1
A0A060T3A1_BLAAD	64.99%	1548	ARAD1C35640p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35640g PE=4 SV=1
A0A161HJE1_9ASCO	64.45%	1426	Myosin 2 OS=Sugiyamaella lignohabitans GN=MYO2 PE=4 SV=1
Q6C7K0_YARLI	58.95%	1564	YALI0E00176p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00176g PE=3 SV=1
A0A1E3PG47_9ASCO	58.44%	1600	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_79749 PE=3 SV=1
UniRef50_A0A1E3PG47	58.44%	1600	Uncharacterized protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PG47_9ASCO
Q5AKW2_CANAL	52.61%	1591	Myosin 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MYO2 PE=3 SV=1
A0A1E4TC48_9ASCO	49.24%	1586	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3849 PE=3 SV=1
MYO2_YEAST	49.69%	1590	Myosin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MYO2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0218

Protein family membership

None predicted.

Domains and repeats

Domain
5 - 66
Myosin S1 fragment, N-terminal (IPR008989)
Domain
9 - 48
Myosin, N-terminal, SH3-like (IPR004009)
Domain
47 - 822
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Myosin head, motor domain (IPR001609)
821 - 870
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
865 - 927
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,214 - 1,491
Dilute domain (IPR002710)

1 200 400 600 800 1000 1200 1400 1591

Detailed signature matches

IPR008989

Myosin S1 fragment, N-terminal
1. SSF50084 (Myosin S1...)
  
  5 - 66
  
  SUPERFAMILY
  SSF50084 (Myosin S1 fragment, N-terminal domain)
IPR004009

Myosin, N-terminal, SH3-like
1. PF02736 (Myosin_N)
  
  9 - 48
  
  Pfam
  PF02736 (Myosin_N)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  865 - 927
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  821 - 870
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  47 - 822
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR001609

Myosin head, motor domain
1. SM00242 (MYSc_2a)
  
  67 - 773
  
  SMART
  SM00242 (MYSc_2a)
2. PS51456 (MYOSIN_MOTOR)
  
  73 - 772
  
  PROSITE profiles
  PS51456 (MYOSIN_MOTOR)
3. PR00193 (MYOSINHEAVY)
  
  447 - 475
  
  PRINTS
  PR00193 (MYOSINHEAVY)
  
  500 - 528
  
  PRINTS
  PR00193 (MYOSINHEAVY)
  
  160 - 185
  
  PRINTS
  PR00193 (MYOSINHEAVY)
  
  103 - 122
  
  PRINTS
  PR00193 (MYOSINHEAVY)
  
  214 - 241
  
  PRINTS
  PR00193 (MYOSINHEAVY)
4. PF00063 (Myosin_head)
  
  75 - 760
  
  Pfam
  PF00063 (Myosin_head)
IPR002710

Dilute domain
1. PS51126 (DILUTE)
  
  1,214 - 1,491
  
  PROSITE profiles
  PS51126 (DILUTE)
2. PF01843 (DIL)
  
  1,375 - 1,470
  
  Pfam
  PF01843 (DIL)
3. SM01132 (DIL_2)
  
  1,374 - 1,474
  
  SMART
  SM01132 (DIL_2)
IPR000048

IQ motif, EF-hand binding site
1. PS50096 (IQ)
  
  823 - 852
  
  PROSITE profiles
  PS50096 (IQ)
  
  871 - 898
  
  PROSITE profiles
  PS50096 (IQ)
  
  798 - 827
  
  PROSITE profiles
  PS50096 (IQ)
2. PF00612 (IQ)
  
  847 - 866
  
  Pfam
  PF00612 (IQ)
  
  825 - 844
  
  Pfam
  PF00612 (IQ)
  
  873 - 891
  
  Pfam
  PF00612 (IQ)
3. SM00015 (iq_5)
  
  845 - 867
  
  SMART
  SM00015 (iq_5)
  
  822 - 844
  
  SMART
  SM00015 (iq_5)
  
  774 - 796
  
  SMART
  SM00015 (iq_5)
  
  797 - 819
  
  SMART
  SM00015 (iq_5)
  
  870 - 892
  
  SMART
  SM00015 (iq_5)

no IPR

Unintegrated signatures

Coil

1,272 - 1,292

COILS
Coil (Coil)

1,005 - 1,074

COILS
Coil (Coil)

938 - 972

COILS
Coil (Coil)
G3DSA:1.10.28...

919 - 1,075

GENE3D
G3DSA:1.10.287.620 (G3DSA:1.10.287.620)
G3DSA:1.20.5.190

811 - 831

GENE3D
G3DSA:1.20.5.190 (G3DSA:1.20.5.190)

858 - 879

GENE3D
G3DSA:1.20.5.190 (G3DSA:1.20.5.190)
G3DSA:3.40.50...

105 - 322

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
G3DSA:4.10.27...

880 - 918

GENE3D
G3DSA:4.10.270.10 (G3DSA:4.10.270.10)

771 - 810

GENE3D
G3DSA:4.10.270.10 (G3DSA:4.10.270.10)

832 - 857

GENE3D
G3DSA:4.10.270.10 (G3DSA:4.10.270.10)
cd01380 (MYSc_Myo5)

87 - 760

CDD
cd01380 (MYSc_Myo5)
cd15480 (fMyo2p_CBD)

1,144 - 1,540

CDD
cd15480 (fMyo2p_CBD)
mobidb-lite (disord...)

611 - 636

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

purine-binding loo...

114N

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

115P

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

116F

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

117Q

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

118K

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

119I

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

120D

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

122L

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)

123Y

purine-binding loop
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y
CDD
cd01380 (MYSc_Myo5)
ATP binding site c...

114N

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

115P

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

116F

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

117Q

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

118K

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

119I

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

120D

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

122L

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

123Y

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

167G

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

168E

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

169S

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

170G

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

171A

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

172G

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

173K

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

174T

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

222A

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

223K

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

224T

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

225T

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

226R

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

227N

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

228D

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

229N

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

230S

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

231S

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

232R

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

452D

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

453I

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

454Y

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

455G

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

456F

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)

457E

ATP binding site
114N, 115P, 116F, 117Q, 118K, 119I, 120D, 122L, 123Y, 167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T, 222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R, 452D, 453I, 454Y, 455G, 456F, 457E
CDD
cd01380 (MYSc_Myo5)
P-loop cd01380

167G

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

168E

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

169S

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

170G

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

171A

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

172G

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

173K

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)

174T

P-loop
167G, 168E, 169S, 170G, 171A, 172G, 173K, 174T
CDD
cd01380 (MYSc_Myo5)
switch I region cd...

222A

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

223K

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

224T

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

225T

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

226R

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

227N

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

228D

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

229N

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

230S

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

231S

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)

232R

switch I region
222A, 223K, 224T, 225T, 226R, 227N, 228D, 229N, 230S, 231S, 232R
CDD
cd01380 (MYSc_Myo5)
putative phosphory...

397E

putative phosphorylation site
397E
CDD
cd01380 (MYSc_Myo5)
switch II region c...

452D

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

453I

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

454Y

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

455G

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

456F

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

457E

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

458H

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

459F

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)

460K

switch II region
452D, 453I, 454Y, 455G, 456F, 457E, 458H, 459F, 460K
CDD
cd01380 (MYSc_Myo5)
relay loop cd01380

481N

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

482Q

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

483H

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

484V

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

485F

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

486K

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

487L

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

488E

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

489Q

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

490D

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

491E

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

492Y

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

495E

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

496E

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

497I

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

498E

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

499W

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

500T

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

501F

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

502I

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

503D

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)

504F

relay loop
481N, 482Q, 483H, 484V, 485F, 486K, 487L, 488E, 489Q, 490D, 491E, 492Y, 495E, 496E, 497I, 498E, 499W, 500T, 501F, 502I, 503D, 504F
CDD
cd01380 (MYSc_Myo5)
SH1 helix cd01380

693G

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

694V

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

695L

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

696E

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

697T

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

698I

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

699R

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

700I

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

701S

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

702C

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)

703D

SH1 helix
693G, 694V, 695L, 696E, 697T, 698I, 699R, 700I, 701S, 702C, 703D
CDD
cd01380 (MYSc_Myo5)
converter subdomai...

714F

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

715A

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

716D

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

717R

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

718Y

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

719Y

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

720L

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

721L

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

722I

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

723P

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

724S

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

745A

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

746A

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

747K

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

748D

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

749K

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

750Y

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

751Q

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

752L

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

753G

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

754K

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

755T

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

756K

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

757I

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

758F

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

759F

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

760R

converter subdomain
714F, 715A, 716D, 717R, 718Y, 719Y, 720L, 721L, 722I, 723P, 724S, 745A, 746A, 747K, 748D, 749K, 750Y, 751Q, 752L, 753G, 754K, 755T, 756K, 757I, 758F, 759F, 760R
CDD
cd01380 (MYSc_Myo5)

Protein sequence

>MCA_04214_1
MVAAYEPETRCWVKDDKEGWIGAVIESKKEDGDKIILTLKSEQNEEITIETNAKEIAEESENLPPLRNPPILEATEDLTS
LSYLNEPAVLHAIRMRYRQLNIYTYSGIVLIATNPFQKIDSLYTPDLIQAYSGKRRGELEPHLFAIAEDAYRCMLRDKSN
QTIVVSGESGAGKTVSAKFIMRYFATVEDPDHPRKKSGNDSLSRTEEQILATNPIMEAFGNAKTTRNDNSSRFGKYLEIL
FNDDIDIIGAKIRTYLLERSRLVFQPAVERNYHIFYQLCAGASESEKEELGLTSVEDFHYLNQGGEPKLQNVDDAEEFAV
TKSALHTIGIDATVQMEIFKILAALLHMGNIEITPSRTNAVLSSDEPSLVKACKILGIDPVSFAKWTTKKQIVTRSEKII
SNLNHQQATVVRDSVAKYIYSALFDWLVYNINQGLCSDEIQSQAKSFIGVLDIYGFEHFKKNSFEQFCINYANEKLQQEF
NQHVFKLEQDEYMREEIEWTFIDFSDNQPCITLIEAKLGILSLLDEESRLPAGSDQSWVEKLYQNFDKPDHNKFFKKPRF
GRSSFIVNHYAMEVTYESEGFIEKNRDTVPDEHLEVLMATENEFLKTVLDFNQQPTAPPPPPPADDKKPGPLKRATVNRK
PTLGGIFKSSLIELMQTINSTNVHYIRCIKPNDAKEAWSFDGPMVLSQLRACGVLETIRISCDGFPTRWTYEEFADRYYL
LIPSTDWANDDVKDFCKIILEKCIAAKDKYQLGKTKIFFRAGMLAWLENLRAARLNECAIIIQKNLRMIYWRRQYDNIRK
SIISVQSAARAFIARKKAQDLREQNAAITIQRLWRGYAQRTSFQKTRNSIIALQCVAKGWLVRNRLLQKRHNDAATTIQN
AWRGYVCRKEYNATRRKICLVQGLWRIKLAKRQLNILREEARSVTHYQEVQYHLESKVVQLTQNLTDHRKENKKLKDVIE
TLNDQLSIWKTKHAESAALVASLEAQSNETKKSNYETVTAIQSKLDALTKQYDQAVTNYEALEKEKQRIEEVLAEKEQAL
VASQETIKDYEQSNNNLLDTVEELRRNLEQVTAKASISAIDLGLSNAAVMANKRNNNRRRSLVGTQFSDKEPSSFAPRPA
SVMYTDLKRSPAEEADEEDEFNLINDELEKILDNFKVLCDEVVQGVIYNLKIPVPPSADDVQPKEILFPAHIISMVTSEM
WRMGYVKESEAFLGQVMHAIQETVLKFSGEEIINPGAFWISNVHEIWSFICVAQENIVSNELLRNEMGMEMFQEYNKLVE
IAKQDLENLEFNIYHAWMRELKKTLDKIIVPAVVLSQSLPGFITLENTRFLTKMFASKESQPATMDTLLSLFNKVYKAMT
GYLLGPDFIKTPMMELLKLVGVKSFNDLLMRRNFASWKRGLQINYNLTRIEEWCKAHDISEGIIQLEHITESVKLLQLRK
STVEDIDIIFDICWTLTPKQIQRLISQYFTADYEPPIPDEILNEVAARVKTDSSTPLMLESGSLDDSGPYEMCDPRPLQR
LESYVPGWLQVPNVKRLCELTALANSQNMQVGGGLTGREEMYVDDIKEMDEGLEYTQQGMNGRSNFEGVAN

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding

Cellular Component

GO:0016459 myosin complex

Filter view on

Entry type

Status

Per-residue features