Protein

MCA_04206_1

Length
534 amino acids

Gene name: PCM1

Description: Phosphoacetylglucosamine mutase

Browser: contigC:2344495-2346202-

RNA-seq: read pairs 14250, FPKM 329.1, percentile rank 92.4% (100% = highest expression)

Protein function

Annotation:PCM1Phosphoacetylglucosamine mutase
KEGG:K01836PGM3 phosphoacetylglucosamine mutase [EC:5.4.2.3]
EGGNOG:0PHNAPCM1Phosphoacetylglucosamine mutase
SGD closest match:S000000784PCM1Phosphoacetylglucosamine mutase
CGD closest match:CAL0000181233AGM1Phosphoacetylglucosamine mutase

Protein alignments

%idAln lengthE-value
MIA_02723_186.14%5340.0MIA_02723_1
A0A0J9XF82_GEOCN79.03%5340.0Phosphoacetylglucosamine mutase OS=Geotrichum candidum GN=BN980_GECA11s02991g PE=3 SV=1
A0A060T1B3_BLAAD69.07%5270.0Phosphoacetylglucosamine mutase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18942g PE=3 SV=1
A0A167FDD7_9ASCO66.98%5240.0Phosphoacetylglucosamine mutase OS=Sugiyamaella lignohabitans GN=PCM1 PE=3 SV=1
A0A1E3PSZ2_9ASCO63.50%5260.0Phosphoacetylglucosamine mutase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81469 PE=3 SV=1
Q6C454_YARLI62.83%5300.0Phosphoacetylglucosamine mutase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E29579g PE=3 SV=1
UniRef50_G7E99554.73%5280.01,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase n=3 Tax=Dikarya TaxID=451864 RepID=G7E995_MIXOS
A0A1E4TLF7_9ASCO56.74%5270.0Phosphoacetylglucosamine mutase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_89117 PE=3 SV=1
Q5AKW4_CANAL54.04%5440.0Phosphoacetylglucosamine mutase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AGM1 PE=3 SV=1
AGM1_YEAST51.34%5222e-159Phosphoacetylglucosamine mutase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCM1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0488
Predicted cleavage: 57

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 500 534

Detailed signature matches

  1. Family IPR016657
    Phosphoacetylglucosamine mutase
    1. PIRSF016408 (PAGM)
    2. cd03086 (PGM3)
  2. Domain IPR016055
    Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
    1. SSF53738 (Phosphogl...)
  3. Domain IPR005844
    Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
    1. PF02878 (PGM_PMM_I)
  4. Domain IPR005843
    Alpha-D-phosphohexomutase, C-terminal
    1. SSF55957 (Phosphogl...)
    2. PF00408 (PGM_PMM_IV)
    3. G3DSA:3.30.31...
  5. SITE IPR016066
    Alpha-D-phosphohexomutase, conserved site
    1. PS00710 (PGM_PMM)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.12...

Residue annotation

  1. active site cd03086
  2. metal binding site...
  3. substrate binding ...

Protein sequence

>MCA_04206_1
MPQLKNLHELSAKHPKPSNLVFSYGTAGFRMKANILDSTIFRVGILATLRSQYLRNQVIAVMITASHNPPEDNGVKLIDP
QGEMLEASWESYATSFANANSNAEIEKIYAHLVKTLNIDTSLPGRVIYGRDSRESGPALVAALEDGFKVSGAQVADYGLV
TTPQLHYIVKCLNTQNTPTPYGQPTEIGYYEKLAEAYKKVLAGYNKTYSITVDAANGIGGPKVKELAKHLSGLVNIAVVN
DKFDEPALLNSNCGADFVKTGQKLPANVDPVSLKLYASFDGDADRIVFFFVDKEGTFKLLDGDKIATLCASFLGDLVQQS
GADLKIGVVQTAYANGSSTHYLTSTLKVPVECTATGVKHLHHAAQHFDIGIYFEANGHGTVLFDPSAITTLQSYEASSPA
QKSAIDSLLALSDLINQTVGDAISDLLLVLAILTIKDWSPSDWDSCYTDLPNRLSKVEVKDRTIFTTTDAERRLVSPPEL
QPKIDDLVKKFPKGRSFVRASGTENVVRVYAEAASRVQADELALKVCHLLEAYQ

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0071704 organic substance metabolic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0004610 phosphoacetylglucosamine mutase activity
GO:0016868 intramolecular transferase activity, phosphotransferases

Cellular Component

None predicted.