Protein

MCA_04162_1

Length
359 amino acids


Browser: contigC:2239546-2240764+

RNA-seq: read pairs 754, FPKM 25.9, percentile rank 48.5% (100% = highest expression)

Protein function

KEGG:K10684UBLE1A ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
EGGNOG:0PGH4PGUG_00106SUMO activating enzyme
SGD closest match:S000006384AOS1DNA damage tolerance protein RHC31
CGD closest match:CAL0000190409CAALFM_CR02770CAE1 ubiquitin-activating protein

Protein alignments

%idAln lengthE-value
A0A0J9X4B4_GEOCN46.53%3469e-101Similar to Saccharomyces cerevisiae YPR180W AOS1 Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p, which may play a role in protein targeting OS=Geotrichum candidum GN=BN980_GECA02s03827g PE=4 SV=1
UniRef50_A0A0J9X4B446.53%3462e-97Similar to Saccharomyces cerevisiae YPR180W AOS1 Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p, which may play a role in protein targeting n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4B4_GEOCN
MIA_02342_144.54%3663e-95MIA_02342_1
A0A060T989_BLAAD40.00%3308e-76ARAD1C36080p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36080g PE=4 SV=1
A0A167CYY0_9ASCO37.54%3416e-74E1 ubiquitin-activating protein AOS1 OS=Sugiyamaella lignohabitans GN=AOS1 PE=4 SV=1
RHC31_YEAST36.99%3463e-70DNA damage tolerance protein RHC31 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AOS1 PE=1 SV=1
A0A1E4TBV4_9ASCO38.26%3453e-61Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3848 PE=4 SV=1
Q6C4B8_YARLI34.34%3645e-58YALI0E28182p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28182g PE=4 SV=1
A0A1E3PKZ3_9ASCO32.35%3406e-50Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50789 PE=4 SV=1
A0A1D8PSA4_CANAL25.77%3923e-44E1 ubiquitin-activating protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR02770CA PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1204

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 359

Detailed signature matches

    1. PR01849 (UBIQUITINACT)
    1. PF00899 (ThiF)
    2. SSF69572 (Activatin...)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MCA_04162_1
MTETSTDPSTQPTNSISSDEVALYDRQIRLWGLEAQARMKNSKILVVGMTGLANEIIKNLVLAGIGSLTILDNAKVTPID
LGSEFFIRDDDIGKFRAKAAVSEISKLNPRVQVSAVCEDIKAQSEEWISQFDVTVGCNLPSFSDTKFLDEITHKAGKAFY
SAGVGGLFGYIFADLGPEYSYSLEQERANIASKVGPINSTSEIVSITSKKDEGTKKFQDTLLIKEKYRKLADLVENVKTL
GPRFASKKRAANVNPVFLLYLSLWRLQLAEKPVSEDSIKEEAVALCSILGLPQQLVDDNASTIPAFLSTINIEIAPVASI
IGGVLAQEVLNTISQKQNPLQNLFIFNGDATAGPVYKLE

GO term prediction

Biological Process

GO:0006464 cellular protein modification process

Molecular Function

GO:0008641 small protein activating enzyme activity

Cellular Component

None predicted.