Protein

MCA_04157_1

Length
855 amino acids

Gene name: RAD16A

Description: DNA repair protein RAD16

Browser: contigC:2218512-2221194-

RNA-seq: read pairs 2215, FPKM 32.0, percentile rank 54.5% (100% = highest expression)

Protein function

Annotation:RAD16ADNA repair protein RAD16
KEGG:K15083RAD16 DNA repair protein RAD16
EGGNOG:0PHZDRAD16repair protein RAD16
SGD closest match:S000000318RAD16DNA repair protein RAD16
CGD closest match:CAL0000195175RAD16DNA repair protein

Protein alignments

%idAln lengthE-value
MIA_01507_172.89%6750.0MIA_01507_1
A0A0J9XA33_GEOCN69.63%6520.0Similar to Saccharomyces cerevisiae YBR114W RAD16 Protein that recognizes and binds damaged DNA in an ATP-dependent manner (With Rad7p) during nucleotide excision repair OS=Geotrichum candidum GN=BN980_GECA05s04960g PE=4 SV=1
A0A1E3PGF1_9ASCO68.27%6650.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26816 PE=4 SV=1
A0A167EEY9_9ASCO67.41%6690.0DNA repair protein RAD16 OS=Sugiyamaella lignohabitans GN=RAD16 PE=4 SV=1
A0A060TI47_BLAAD69.02%6650.0ARAD1D36102p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36102g PE=4 SV=1
Q6C3A7_YARLI66.17%6680.0YALI0F01232p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01232g PE=4 SV=1
RAD16_YEAST66.77%6470.0DNA repair protein RAD16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD16 PE=1 SV=1
UniRef50_P3124466.77%6470.0DNA repair protein RAD16 n=32 Tax=Ascomycota TaxID=4890 RepID=RAD16_YEAST
Q5AI84_CANAL66.37%6690.0DNA repair protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RAD16 PE=4 SV=1
A0A1E4TFH1_9ASCO61.38%6500.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31446 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1018

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 855

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR000330
    SNF2-related, N-terminal domain
    1. PF00176 (SNF2_N)
  4. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  5. Domain IPR001841
    Zinc finger, RING-type
    1. SM00184 (ring_2)
    2. PS50089 (ZF_RING_2)
  6. Domain IPR018957
    Zinc finger, C3HC4 RING-type
    1. PF00097 (zf-C3HC4)
  7. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  8. SITE IPR017907
    Zinc finger, RING-type, conserved site
    1. PS00518 (ZF_RING_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. G3DSA:3.40.50...
  4. SSF57850 (RING/U-box)
  5. cd00046 (DEXDc)
  6. cd00079 (HELICc)
  7. cd16567 (RING-HC_RA...)
  8. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. Zn binding site cd...
  4. nucleotide binding...
  5. ATP-binding site c...

Protein sequence

>MCA_04157_1
MPPKRKTRSATTASKHDNDEILEQYDEDTAGGFIPEPPKKRQRKGKTVAKKSKVIDLSPPISQADSGASTPDPQVTAPTS
VSPDEEDSDSILTIPMSSKQARTLSRASRRSRRSSAKVTYTGLDTESNDDEESDDDYKEEEEKENEDNEADEEEKQETVK
EEITTAEPETLAPAKPRRRRRARTTQPPSTGPRPSRYEALMARIRQGLYDHHPHLENVFERIEAEGDITPKAIDQPPGMT
IQLLPFQKEGLNWLIQQEKSRYKGGILADEMGMGKTIQTVALFMSDDPATRSGPNLVIAPTVALMQWKNEIDSHTGGALK
VLIYHGRTKTVSKAELLKYDVILTTYSLLESVYRKQQSGFKRKGETVKEKSVLHNIEFHRVVLDEAHNVKDRHSSTTRAV
SSLTTERRLCLSGTPLQNRIGELYSLLKFLKVRPLSQYFCRKCECESDTWDFQGSKCRSCGHLHLFHTNFFNHSILHHLQ
RERVEGGANESMKHLRLLLKRLMLRRTKIERADDLGLPPRVVEIRRDFFNEEEKDLYESIYSDSTRKFNTYVAQGVVLNN
YANIFTLITRMRQLSDHPDLVLKRHLTDEGMVVNTIVCQLCDDEAEEPIESKCHHTFCRTCITEYVQGWTGEASELQCPV
CHIGLSIDLTAPAMVSEVSSADTKKSKSSIINRINMTGGWRSSTKIEALVEELYKLRNNRQTIKSIVFSQFTSMLDLVEW
RLNKAGFQTVKLKGSMSPIQRDAIINHFMSTPAVEVFLVSLKAGGVALNLCEASQVFIMDPWWNPSVEWQSGDRVHRIGQ
HRPVKITRLIIEDSIESRIVELQEKKATMINATISQDDSAMQRLTPADMQFLFQI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding
GO:0046872 metal ion binding

Cellular Component

None predicted.