Protein

MCA_04145_1

Length
636 amino acids

Gene name: PLB1D

Description: Lysophospholipase

Browser: contigC:2178274-2180185-

RNA-seq: read pairs 53713, FPKM 1041.9, percentile rank 96.6% (100% = highest expression)

Protein function

Annotation:PLB1DLysophospholipase
KEGG:K13333PLB lysophospholipase [EC:3.1.1.5]
EGGNOG:0PFXAPLB1Lysophospholipase
SGD closest match:S000005371PLB3Lysophospholipase 3
CGD closest match:CAL0000188254PLB3Lysophospholipase

Protein alignments

%idAln lengthE-value
MIA_04305_165.78%5670.0MIA_04305_1
A0A0J9XEK4_GEOCN60.42%6240.0Lysophospholipase OS=Geotrichum candidum GN=BN980_GECA12s01258g PE=3 SV=1
A0A167CL27_9ASCO54.06%6160.0Lysophospholipase OS=Sugiyamaella lignohabitans GN=PLB1 PE=3 SV=1
UniRef50_A0A167CL2754.06%6160.0Lysophospholipase n=3 Tax=saccharomyceta TaxID=716545 RepID=A0A167CL27_9ASCO
A0A060TBV8_BLAAD57.02%5630.0Lysophospholipase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35024g PE=3 SV=1
A0A1E3PR46_9ASCO51.96%6370.0Lysophospholipase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80931 PE=3 SV=1
Q6C5Q6_YARLI52.17%6210.0Lysophospholipase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16060g PE=3 SV=1
A0A1D8PU17_CANAL50.00%6220.0Lysophospholipase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PLB3 PE=3 SV=1
PLB3_YEAST48.17%6290.0Lysophospholipase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PLB3 PE=3 SV=1
A0A1E4THQ4_9ASCO34.51%5396e-97Lysophospholipase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31966 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0111

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 636

Detailed signature matches

  1. Domain IPR016035
    Acyl transferase/acyl hydrolase/lysophospholipase
    1. SSF52151 (FabD/lyso...)
  2. Domain IPR002642
    Lysophospholipase, catalytic domain
    1. PS51210 (PLA2C)
    2. SM00022 (pla2_6)
    3. PF01735 (PLA2_B)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.10...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SignalP-noTM
  8. cd07203 (cPLA2_Fung...)

Residue annotation

  1. active site cd07203
  2. nucleophile elbow ...
  3. flexible lid regio...

Protein sequence

>MCA_04145_1
MTPILSHIYLISSLAALTAAWNPSNEYAPSFVECPSSDFNLYRPANRGLLEQERDWVEERHKQTDPALKDFIKRVKMENF
DVDSFMGSNTSINLGLAFSGGGYRAMICGAGQFAALDNRTEGSTEDGHLGGLVQSATYLAGLSGGSWLVGSIMFNNFTSI
GDLMTNGDIWDLKHSIINPGGINIFSTAKYYDDLTDEVEEKKDKGFNISITDIWGRALSQQFIDLPNGGPGMAMSDIQNF
PPFVNHESPFPFFVACGRAPNTKIISLNSTVFEFGPYELGSWDPHVYGFANMTYIGTDVENGKPKNDSACVVGFDQAGFA
MGTSSSLFNQFILQINETGVNGVLYKLAMSILTDLDEDENDIAAYNPNPFYKTNEHTIAQDPDLDLVDGGEDLQNVPFYP
LIQPERKVDVIMAYDNSADTDYNWPNGASIQATYARQFGAQGNGTYFPYVPDNNTFVNLGFNKRPVFFGCYASNFTSLRQ
EVNATDLDWVPPVIVYTSNSYYTYNSNKTTFTLSYERDEMVKMIENTYATATRGNGTIDSEFPACVACAIVQREFERRGL
PQTEQCKRCFDNYCWNGTLNNTVPTVIDSNSLQAAQSNSESGKSGDDGKKNSASIAQVDTFKVLSMAILIAITFVL

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009395 phospholipid catabolic process

Molecular Function

GO:0004620 phospholipase activity

Cellular Component

None predicted.