Protein

MCA_04117_1

Length
1,595 amino acids


Gene name: RPA190

Description: DNA-directed RNA polymerase I subunit RPA190

Browser: contigC:2100340-2105203-

RNA-seq: read pairs 4221, FPKM 32.7, percentile rank 55.1% (100% = highest expression)

Protein function

Annotation:RPA190DNA-directed RNA polymerase I subunit RPA190
KEGG:K02999RPA1 DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
EGGNOG:0PG11PGUG_03709DNA-directed RNA Polymerase
SGD closest match:S000005868RPA190DNA-directed RNA polymerase I subunit RPA190
CGD closest match:CAL0000187313RPA190DNA-directed RNA polymerase subunit

Protein alignments

%idAln lengthE-value
MIA_02674_173.92%16220.0MIA_02674_1
A0A0J9XFU2_GEOCN64.43%16360.0DNA-directed RNA polymerase subunit OS=Geotrichum candidum GN=BN980_GECA15s00890g PE=3 SV=1
A0A060T2W2_BLAAD61.41%16690.0DNA-directed RNA polymerase subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03894g PE=3 SV=1
A0A1E3PT11_9ASCO60.18%16650.0DNA-directed RNA polymerase subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49068 PE=3 SV=1
RPA1_YEAST59.93%16670.0DNA-directed RNA polymerase I subunit RPA190 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPA190 PE=1 SV=2
UniRef50_P1096459.93%16670.0DNA-directed RNA polymerase I subunit RPA190 n=104 Tax=cellular organisms TaxID=131567 RepID=RPA1_YEAST
A0A1D8PEX3_CANAL59.75%16670.0DNA-directed RNA polymerase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPA190 PE=3 SV=1
A0A167F7U6_9ASCO60.34%15760.0DNA-directed RNA polymerase I core subunit RPA190 OS=Sugiyamaella lignohabitans GN=RPA190 PE=4 SV=1
Q6C1S4_YARLI58.18%16500.0DNA-directed RNA polymerase subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13783g PE=3 SV=1
A0A1E4TEP2_9ASCO55.46%16680.0DNA-directed RNA polymerase subunit OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103917 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0355

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1595

Detailed signature matches

    1. PF04997 (RNA_pol_Rp...)
    1. SM00663 (rpolaneu7)
    1. PF00623 (RNA_pol_Rp...)
    1. PF04983 (RNA_pol_Rp...)
    1. PF05000 (RNA_pol_Rp...)
    1. PF04998 (RNA_pol_Rp...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF64484 (beta and ...)
  2. cd01435 (RNAP_I_RPA1_N)
  3. cd02735 (RNAP_I_Rpa1_C)
  4. mobidb-lite (disord...)

Residue annotation

  1. Zn-binding cd01435
  2. putative active si...
  3. catalytic site cd0...
  4. Rpb1 (Rpa1) - Rpb6...
  5. cleft cd02735
  6. Rpb1 (Rpa1) - Rpb2...
  7. DNA binding site c...
  8. Rpb1 (Rpa1) - Rpb5...
  9. clamp cd02735

Protein sequence

>MCA_04117_1
MDASFPTGTQIESVDFRVLSSKEVERLSVKQITSAEVFDALGHPVPGGLYDLSLGAFLKNICTTCGLDERFCPGHMGHID
LPVPVYNPLFFSQIYTLLRGTCVYCRHFKLDRLTTNAYECKLRLIQYGLFAEISEFETLISQESSQKLAVSSTSERGMYN
GEIIKVRNKFVNDLINTALKEGRTSENGLLTPALNDERRNLIKAFYNEIKARNTCLNCEMVNPKYRKEGSIKIFELALSQ
KDFQKNSAKSATRNRLQGMPKKGNAAIKHNTNETRYLSSNEVLQLFNSVFRNESDICNVLFHTRPNDSTKLTGEMFFMQK
LVVTPTRFRLPSKVGDMVHTNPKNDLLSSIISACFRIRDLNKSLASEDSTNQQFDYLINAFAQLQGEVNGYIDSTKSQSR
SGKILPGVKQTLEKKEGLFRKNMMGKRVNYAARSVISPDPNLETNEIGIPPVFAVNLTYPEPVTQHNYQEMRQAVINGPE
LWPGATAVQDETGQLVKLAGMSVEERTAVANQLMTPSSTGSVINKKVYRHINNGDVVLMNRQPTLHKASMMGHKAHILPG
EKTLRLHYANTGAYNADFDGDEMNMHFPQNEAARAEAMLIANTDSQYLTPTSGKPLRGLIQDHISAGVILTSKDTFFTRE
KYQQLVYGCLRPEDGHTTSGKILTVPPAIIKPVPMWTGKQVITTALLNITPNGMDGINLKSKNKIKNDYWGEGSTENEVI
FKNGELVCGILDKSQYGAADNGIVHSVFEVYGNDTAGKLLSVLGRLFTRYITSVGFTCGMDDLYLTKEGDAWRKEILEKA
SDVGLKAAAEVTNLNEDVSEDDPEFIRRLEEILRDDQKLGILDAITQSKVNTVASSIVSKCVPDGTAKRFPINSMQSMAL
SGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPFETKARAGGYIAQRFFSGIRPQEYYFHCMAGREGLIDTA
VKTSRSGYLQRCLIKQLEGVQVSYDNSVRDSDGTLIQFMYGGDSVDVIKESHLTNFQFCYDNFESLLKRHKPTNIDHIEL
KEALGYAKKALKHYKRHANDPHYEFLPKYDPVTSVYNPSKYVGSVSDTFQEKLEKFVKENSSLFTQGNITEKKFTTLMQL
KYMGSLVDPGEAVGIIASESIGEPSTQMTLNTFHFAGHGAANVTLGIPRMREIIMTASPNIMTPQMTLPILDHINDEQAD
IFCKNVGRILLSEVVDKVTVTETRTSSGSIHNRAYHIRLDFYTREEYENEYDISDFHVLKCVTNGFLVSLESSIKKEFKR
FGKNDNSIGVALKPSETYVESSKADEDGADEEIQRSKKTQAVSYDGPDEGDMEVIRNAADEGSDNEADEEDSDDDSEDES
NNRKAKAASVSKDIKSREMAIIERFKHVSSFKFDDVNGQWCEITLEYAADSPKILMVGIIEDVCRSTVIREIPNIGRCIR
PSADQNDGKRVLVTEGVNFNAMWEEDTFIDVDGILSNDVAAVLRTYGVEAARNTIVREINNVFKTYAISVNLRHLDLIAD
MMTRDGTYLAFNRFGMKSMTSPFLKMSFETTCNFLTEAVLNTEYDDLQSPSSRIVVGKASKVGTGSFDVLTSLFQ

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity

Cellular Component

None predicted.