Protein

MCA_04101_1

Length
729 amino acids


Browser: contigC:2018443-2020633+

RNA-seq: read pairs 17277, FPKM 292.4, percentile rank 91.6% (100% = highest expression)

Protein function

KEGG:K01885EARS glutamyl-tRNA synthetase [EC:6.1.1.17]
EGGNOG:0PHA7FG04582.1Glutamyl-tRNA synthetase
SGD closest match:S000003214GUS1Glutamate--tRNA ligase, cytoplasmic
CGD closest match:CAL0000193213GUS1Glutamate--tRNA ligase

Protein alignments

%idAln lengthE-value
MIA_02595_181.16%7270.0MIA_02595_1
A0A0J9XAA2_GEOCN76.24%7280.0Similar to Saccharomyces cerevisiae YGL245W GUS1 Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p OS=Geotrichum candidum GN=BN980_GECA06s04817g PE=3 SV=1
A0A1E3PDH5_9ASCO71.11%7270.0Glutamyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84433 PE=3 SV=1
A0A167DZB5_9ASCO68.21%7330.0Glutamate--tRNA ligase GUS1 OS=Sugiyamaella lignohabitans GN=GUS1 PE=3 SV=1
A0A060TCX7_BLAAD66.53%7320.0ARAD1D46530p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D46530g PE=3 SV=1
Q6C4A4_YARLI65.24%7220.0YALI0E28468p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28468g PE=3 SV=1
A0A1D8PQL8_CANAL63.42%7300.0Glutamate--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GUS1 PE=3 SV=1
SYEC_YEAST62.24%7230.0Glutamate--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUS1 PE=1 SV=3
UniRef50_P4665562.24%7230.0Glutamate--tRNA ligase, cytoplasmic n=149 Tax=Ascomycota TaxID=4890 RepID=SYEC_YEAST
A0A1E4THI3_9ASCO65.52%6410.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44829 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0569
Predicted cleavage: 15

Protein family membership

Domains and repeats

Detailed signature matches

    1. PR00987 (TRNASYNTHGLU)
    1. MF_02076 (Glu_tRNA_...)
    1. SSF47616 (GST C-ter...)
    1. PF00749 (tRNA-synt_1c)
    1. SSF50715 (Ribosomal...)
    1. PF03950 (tRNA-synt_...)
    1. PS00178 (AA_TRNA_LI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52374 (Nucleotid...)
  2. cd00807 (GlnRS_core)
  3. cd10306 (GST_C_GluRS_N)
  4. mobidb-lite (disord...)

Residue annotation

  1. putative protein i...
  2. Arc1p interface cd...
  3. active site cd00807
  4. HIGH motif cd00807
  5. KMSKS motif cd00807

Protein sequence

>MCA_04101_1
MSDYKLVLAGKARLVAYADLIAAAVINHLQPTSPITFSVVDEPVIKKDIADSTSALTLPDNSTVYGPAVFSTLAEKFAAD
LYGTDLKTKYSDEWVKFAFSELTVKDFKQLTPALEKLESHLNFRSFIVGYAPAIADIAVWGVLRSNAVVANAVKSGTYIN
IGRWYKFLDSHRLFGGSVETYTKDLTELRKSAKVGQKKESRASFDIDLVDAEEGKVVTRFPPEPSGYLHIGHAKAALLNQ
YFAQLYKGKLIIRFDDTNPSKEKVEFEDSIVEDLKLLGIHGDVVTHSSDYFDTMYNYAIQLIKEGKAYVDDTPVERMREE
RGEGIASARRDRTVEENLKFFEEMKNGTEIGLKSTLRAKISVDNNNKAMRDPVIYRTNLTPHHRTGTQWKIYPTYDFCVP
IVDSIEGVTHALRTIEYRDRNPQYAWFLENLHLRKVHIWDFARVNFQRTLLSKRKLQWFVDNNKVTGWDDPRFPTVRGVR
RRGMTVEGLRNFILATGPSKNIINLEWSMIWATNKKIIDPIAPRHTAITSKDAVKVTLSGGPEKPYSEDKPKHKKNPSLG
NKKVFFSKNVLIDQEDAQVLKEGEEFTFMDWGNAIVEKIHKNSDGIVESIDAKLHLEGDFKTTEKKITWLADTENVTPVE
LVDFDHLINKDKIEEDENFEDFLTEFTEFKTDAIADVNVKDLKKGDIIQFERKGYFRIDTPYSEGGKAILFTIPDGKAVK
RYGAKPVSN

GO term prediction

Biological Process

GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds

Cellular Component

GO:0005737 cytoplasm