Protein

MCA_04064_1

Length
1,072 amino acids

Gene name: SLA2

Description: Protein SLA2

Browser: contigC:1931063-1934282+

RNA-seq: read pairs 7290, FPKM 83.9, percentile rank 76.0% (100% = highest expression)

Protein function

Annotation:SLA2Protein SLA2
KEGG:K20040HIP1R huntingtin-interacting protein 1-related protein
EGGNOG:0PHTBSLA2Cytoskeleton assembly control protein
SGD closest match:S000005187SLA2Protein SLA2
CGD closest match:CAL0000178056SLA2Sla2p

Protein alignments

%idAln lengthE-value
MIA_02435_173.95%6910.0MIA_02435_1
A0A0J9X557_GEOCN64.29%7000.0Similar to Saccharomyces cerevisiae YNL243W SLA2 Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization OS=Geotrichum candidum GN=BN980_GECA02s02540g PE=4 SV=1
A0A060TG10_BLAAD59.91%6910.0ARAD1D19316p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D19316g PE=4 SV=1
A0A167CWQ7_9ASCO58.58%6880.0Sla2p OS=Sugiyamaella lignohabitans GN=SLA2 PE=4 SV=1
UniRef50_A0A1E4TTZ458.92%7010.0Uncharacterized protein n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E4TTZ4_PACTA
A0A1E3PT97_9ASCO56.52%7060.0Endocytic adaptor protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81197 PE=4 SV=1
Q6CCQ4_YARLI55.60%6960.0YALI0C07502p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07502g PE=4 SV=1
A0A1D8PRF5_CANAL42.55%6913e-125Sla2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SLA2 PE=4 SV=1
SLA2_YEAST57.14%2669e-98Protein SLA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLA2 PE=1 SV=5

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0789

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1072

Detailed signature matches

  1. Domain IPR008942
    ENTH/VHS
    1. SSF48464 (ENTH/VHS ...)
    2. G3DSA:1.25.40.90
  2. Domain IPR013809
    ENTH domain
    1. PS50942 (ENTH)
    2. SM00273 (enth_2)
  3. Domain IPR011417
    AP180 N-terminal homology (ANTH) domain
    1. PF07651 (ANTH)
  4. Domain IPR002558
    I/LWEQ domain
    1. PS50945 (I_LWEQ)
    2. PD011820
    3. SSF109885 (I/LWEQ d...)
    4. PF01608 (I_LWEQ)
    5. SM00307 (ILWEQ_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.11...
  3. G3DSA:1.20.14...
  4. G3DSA:1.20.14...
  5. cd03564 (ANTH_AP180...)
  6. mobidb-lite (disord...)

Residue annotation

  1. PtdIns(4,5)P2-bind...

Protein sequence

>MCA_04064_1
MSTKAETDLNAHIRKATNIDETAPKRKHVRACIVFTWDHRSGRAFWSGLKIQPIQADEVQIFKALITIHKVLQEGHPSVL
VEAQQHVSWIERLGRNVSPTGPLGYSRLIQEYVRLLLKKLEFHRIHPDFNGTFEYEEYISLRNIDDPNEGYEAIIDLMNL
QDAIDDFQRIIFASLQQNRANECKISALTPLVAESYGIFRFSTTMIRAMHSTTNDDEAMEPLRSRYYSQYNRLLNFYYDC
STLKYLTSLITIPQLPPDPPNLYGEDVEGEAPALPKRPGTVPPPESDNTSVVTTPAVVSRQVTGAPEPAVDFWSTQAAQQ
QQLQLQQQQQLAQQQQYEEEQRRLQDQRAAEARQQELLRLQQQQQFEEQQRQQAEQQRLAQEALMRDQLQRQAQGRVAEL
ERDLLNLRGMYEQSQLNLQQYDQRVKALENEIQQLNANSNMQLQSKDEMIKSVQEQLNTWKSKYEALAKLYSQLRQEHLD
LLAKFKKVQAKAASAQEAIEKREKLERDIKAKNIELADLIRERDRARYDLDKSRGSNKDQIEKLERELRMTKEKLDDAER
SKGADLSLLLAKHNRELSELEEALKAKQKIIDSYGSRSFDDEGLKERLQEKEDELEIQQEMYHTLSEAFEKLALEKKSST
GSPESINSILDAILKSSADKIQDSLFELESPMEAGNQNATPEYLLSIIEKASSSVFEFFDSFTTYFASLEDDADSATASE
LHTSIVSTTVNSCGAIIDVLSNAKGITRLIRDEAVADNVVNRSQKSARALNEFFLGMCSRNLEGLTTDDKTELLINHNIR
VQQELKQLSDITETLAPKLAQALKANSDKIGDYVDNEMAKLSEAIELANARLNELMVRPKDPSVSQFELNIHNSILSAAQ
AVTSAIAALIKAAIACQQEIVAQGKGSMSTTAFYKKHNKWTEGLISAAKSVAASTNILIETADGVLSSKNSPEQLIVASN
EVAASTAQLVAASRVKTSLYSMSKTQDKLEMASKNVTSACKTLVSQVQDIIAKTNGKDNVDDVDYSKLTPHVLKTTEMEQ
QVEILKLENMLSSARKRLGEIRKFSYIDDDDE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003779 actin binding
GO:0005543 phospholipid binding

Cellular Component

None predicted.