Protein
MCA_04035_1
Length
758 amino acids
Gene name: GFA1
Description: Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Browser: contigC:1820179-1822456-
RNA-seq: read pairs 39251, FPKM 639.0, percentile rank 95.2% (100% = highest expression)
Protein function
| Annotation: | GFA1 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] | |
|---|---|---|---|
| KEGG: | K00820 | glmS | glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] |
| EGGNOG: | 0PG0E | GFA1 | Glucosamine--fructose-6-phosphate aminotransferase |
| SGD closest match: | S000001587 | GFA1 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
| CGD closest match: | CAL0000176261 | GFA1 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00961_1 | 78.67% | 783 | 0.0 | MIA_00961_1 |
| A0A0J9X5B0_GEOCN | 75.56% | 765 | 0.0 | Similar to Saccharomyces cerevisiae YKL104C GFA1 Glutamine-fructose-6-phosphate amidotransferase OS=Geotrichum candidum GN=BN980_GECA03s00351g PE=4 SV=1 |
| Q6CDT1_YARLI | 70.25% | 763 | 0.0 | YALI0B21428p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B21428g PE=4 SV=1 |
| A0A1E3PPE4_9ASCO | 69.92% | 758 | 0.0 | Isomerising glucosamine-fructose-6-phosphate aminotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81744 PE=4 SV=1 |
| A0A1E4TM49_9ASCO | 67.10% | 763 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_49100 PE=4 SV=1 |
| A0A167CQC6_9ASCO | 69.83% | 749 | 0.0 | Glutamine--fructose-6-phosphate transaminase (Isomerizing) GFA1 OS=Sugiyamaella lignohabitans GN=GFA1 PE=4 SV=1 |
| GFA1_CANAL | 64.66% | 764 | 0.0 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GFA1 PE=1 SV=3 |
| UniRef50_P53704 | 64.66% | 764 | 0.0 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] n=822 Tax=Eukaryota TaxID=2759 RepID=GFA1_CANAL |
| GFA1_YEAST | 61.78% | 764 | 0.0 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GFA1 PE=1 SV=4 |
| A0A060TGE1_BLAAD | 78.70% | 446 | 0.0 | ARAD1D29524p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D29524g PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0840
Protein family membership
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
758
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
PF13522 (GATase_6)
-
SSF53697 (SIS domain)
-
cd00714 (GFAT)
-
mobidb-lite (disord...)
Residue annotation
-
glutaminase active...
-
dimer interface cd...
-
active site cd05008
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dimer interface cd...
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active site cd05009
Protein sequence
>MCA_04035_1 MCGIFGYINYLVPKTRAEILNNLLEGLQRQEYRGYDSSGLAVDGEILDKKTGKRDVLIFRQVGKVKALKENIDTEFSKIK PDEVLENHVGIAHTRWATHGQPKTINCHPQRSDENNEFTVVHNGIITNYREIKEFLKQKGYVFESETDTECIAKLTKFIY DSMRKENQTIDFIQLLKLVVKELEGAYGVIIKSTHYPDEVVATRKGSPLLVGVKTEKKLKVDFVDVEFGDTSDSSLLQGA EQSVNTGTLLHHNIGSSNTSSSTANASHNSASRLPVLSIPENGPFDDASAPSVASSDKNSLNVPGRGHASTYMRHSQSRA FLSDDDQPLPIEFFLASDPAAVVEHTRKVLFLEDDDIAHIYDGELHIHRVRRNDDEKPTRSIVTLEMELQQIMKGKFEHF MQKEIFEQPESVINTMRGRIDFENNTVQLGGLRSWLTTIRRCRRIIMIACGTSYHSCLATRSIFEELTEIPVSVELASDF LDRKSPVFRDDTCVFVSQSGETADTMLALQYCLERGALTVGIVNSVGSSISRQTHCGVHINAGPEIGVASTKAYTSQYVA LVLMALSLSDDRVSMIERRKAIIQGLKNISSQIQEVLNLNDEIRELCETRFVDQKSLLLLGRGYQFATALEGALKIKEIS YMHSEGVLAGELKHGVLALVDKDLPIIIMATQDSFFPKVSSAIEQVTARSGNPFIICNKGANKFAEQGLKTLEVPSTVDC LQGLLNVIPLQLMSYWLAVKKGYNVDYPRNLAKSVTVE
GO term prediction
Biological Process
GO:1901135 carbohydrate derivative metabolic process
GO:1901137 carbohydrate derivative biosynthetic process
Molecular Function
GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0097367 carbohydrate derivative binding
Cellular Component
None predicted.