Protein
MCA_03987_1
Length
939 amino acids
Gene name: FCP1
Description: RNA polymerase II subunit A C-terminal domain phosphatase
Browser: contigC:1705249-1708136+
RNA-seq: read pairs 2442, FPKM 32.1, percentile rank 54.6% (100% = highest expression)
Protein function
| Annotation: | FCP1 | RNA polymerase II subunit A C-terminal domain phosphatase | |
|---|---|---|---|
| KEGG: | K15732 | CTDP1 | RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16] |
| EGGNOG: | 0PH1W | FCP1 | RNA polymerase II subunit A C-terminal domain phosphatase |
| SGD closest match: | S000004890 | FCP1 | RNA polymerase II subunit A C-terminal domain phosphatase |
| CGD closest match: | CAL0000184913 | orf19.6742 | Protein serine/threonine phosphatase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01219_1 | 64.72% | 343 | 7e-151 | MIA_01219_1 |
| A0A0J9XJL5_GEOCN | 63.66% | 344 | 1e-139 | Similar to Saccharomyces cerevisiae YMR277W FCP1 Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit OS=Geotrichum candidum GN=BN980_GECA19s01583g PE=4 SV=1 |
| UniRef50_A0A1E3NSF3 | 33.25% | 806 | 3e-123 | Uncharacterized protein n=2 Tax=Pichia membranifaciens TaxID=4926 RepID=A0A1E3NSF3_9ASCO |
| A0A060TEL8_BLAAD | 59.06% | 342 | 6e-126 | ARAD1D15972p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D15972g PE=4 SV=1 |
| Q6C770_YARLI | 54.09% | 342 | 1e-121 | YALI0E03278p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03278g PE=4 SV=1 |
| Q5ADU9_CANAL | 53.64% | 343 | 1e-116 | Protein serine/threonine phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6742 PE=4 SV=1 |
| A0A1E4TKA6_9ASCO | 51.75% | 342 | 6e-105 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30421 PE=4 SV=1 |
| A0A167F3V3_9ASCO | 57.75% | 284 | 8e-101 | Fcp1p OS=Sugiyamaella lignohabitans GN=FCP1 PE=4 SV=1 |
| A0A1E3PN79_9ASCO | 50.62% | 322 | 5e-95 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82224 PE=4 SV=1 |
| FCP1_YEAST | 42.22% | 360 | 2e-80 | RNA polymerase II subunit A C-terminal domain phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FCP1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0208
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
100
200
300
400
500
600
700
800
939
Detailed signature matches
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SSF56784 (HAD-like)
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no IPR
Unintegrated signatures
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cd07521 (HAD_FCP1-like)
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mobidb-lite (disord...)
Residue annotation
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HAD signature moti...
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active site cd07521
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HAD signature moti...
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HAD signature moti...
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HAD signature moti...
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Dimer interface cd...
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BRCT sequence moti...
Protein sequence
>MCA_03987_1 MEMTPATPVSLPSSTLYPVVITALLKNVGDDVPKHTPILRYKYWNFVDDPEAEVEEGEEPRKIEKEFHSTFESPISGKLT EWKIKVGDEVSNPQFFIASITEPCTHPIQYNGLCAQCGKVLDNENDYSEFSNEDRAPINMSHDSSGITISFDEAQRIEKM SSQQLMQNRRLILVVDLDQTVIQADTNPIIGTIQNNPSDANYNTIKEVRSFQLNEEILIPGLNGDSSRRQTSTATYYVKI RPGLKEFLENMYRYYEMHVYTMATRSYAVAIAKIIDPEGKYFGDRILSRDESGSIYQKSLKRLFPVSTAMVAIIDDRGDV WQWSPNLIKVFRYDFFHVGDINAPPPMPNTVVNTTPEITPERDISNDAVDPSFLTNGNKSDSTLDQIPAEEGIVDESAAI ESNTDKHLENSVDENKSNLEPVSDKNDSDVLSIDLFDEDMKTQASSQISATGINGDINTVNSSKIQSSEFYKPLEVSDDT VQSGSGAAENNIASENESCENEPVKVNGNKSISDTELNGISKENYTDEPIDSSNNTIDVLIENNESSLSTNGNSNNFADE IKSTSSDNSNKSESQVSNEQTNALGTILYDNDNELISLEEKLRNLHVEYYREFDRLAVRKGGFSNIEETDLPDVAHILPR MKRVAFNHCVFVFSGLEFGSFDDAEIVQWCRSFGAVVVAEMVDTVTHVIAKNNQSTRARKAFKNPKIKVVSLDWVYKCMS TWQHVPEDKYLLQPPIDEETLTISDEPSSPHNHFNQQNNNVSTNDEEEVLNTESFVMDLTNKSVDWDEMDKELEDFLNSS DEENDEDNDSDVADSLAEERPTTGRKTVSKPLDSIENNDEEEDNDDEDDDDDDEDDDDDDDDDDDEEDDDEDDDNDDEDE NEDNEESNNKEASQKSGIKRLPDSFDNDGSPSKRHKSNASDESENEEHELNEDDIYSVF
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
Cellular Component
GO:0005634 nucleus