Protein

MCA_03970_1

Length
387 amino acids


Gene name: SAM2

Description: S-adenosylmethionine synthase 2

Browser: contigC:1663488-1664652-

RNA-seq: read pairs 21655, FPKM 689.6, percentile rank 95.4% (100% = highest expression)

Protein function

Annotation:SAM2S-adenosylmethionine synthase 2
KEGG:K00789metK S-adenosylmethionine synthetase [EC:2.5.1.6]
EGGNOG:0PJ51SAM2Catalyzes the formation of S-adenosylmethionine from methionine and ATP (By similarity)
SGD closest match:S000002910SAM2S-adenosylmethionine synthase 2
CGD closest match:CAL0000185243SAM2S-adenosylmethionine synthase

Protein alignments

%idAln lengthE-value
MIA_04571_189.72%3890.0MIA_04571_1
A0A0J9XBA7_GEOCN92.51%3870.0S-adenosylmethionine synthase OS=Geotrichum candidum GN=BN980_GECA08s03948g PE=3 SV=1
A0A1E3PLG8_9ASCO91.86%3810.0S-adenosylmethionine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45792 PE=3 SV=1
Q6CEM5_YARLI91.21%3870.0S-adenosylmethionine synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B14509g PE=3 SV=1
A0A167CCR1_9ASCO88.89%3870.0S-adenosylmethionine synthase OS=Sugiyamaella lignohabitans GN=SAM2 PE=3 SV=1
A0A060TA33_BLAAD89.79%3820.0S-adenosylmethionine synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D16148g PE=3 SV=1
A0A1D8PF68_CANAL84.29%3820.0S-adenosylmethionine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAM2 PE=3 SV=1
UniRef50_A0A1V2LGP483.12%3850.0S-adenosylmethionine synthase n=2 Tax=Pichia kudriavzevii TaxID=4909 RepID=A0A1V2LGP4_PICKU
A0A1E4TJ08_9ASCO83.81%3830.0S-adenosylmethionine synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20829 PE=3 SV=1
METK2_YEAST78.95%3800.0S-adenosylmethionine synthase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAM2 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0273

Protein family membership

Domains and repeats

1 50 100 150 200 250 300 350 387

Detailed signature matches

    1. MF_00086 (S_AdoMet_...)
    1. SSF55973 (S-adenosy...)
    1. PF00438 (S-AdoMet_s...)
    1. PF02772 (S-AdoMet_s...)
    1. PF02773 (S-AdoMet_s...)
    1. PS00377 (ADOMET_SYN...)
    2. PS00376 (ADOMET_SYN...)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MCA_03970_1
MTAPAAENTFFFTSESVGEGHPDKICDQVSDAILDACLKEDPLSKVACETAAKTGMIMVFGEITTSAKLDFQKIVRDTIK
HIGYDHSEKGFDYKTCNVLVAIEQQSPDIAQGLHYEKALEELGAGDQGIMFGYATDETEELLPLTVILSHKLNAALAAAR
RDGSLGWLRPDTKTQVTVQYKLDNGACVPIRVDTVVVSTQHSDDISTEDLRREILEKIIKKVIPANLLDDNTKYHIQPSG
RFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYAARWVAKSLVAAGLARRALVQFSYAIGVAEPL
SIFVDTYGTSEKTSDELVQIIRNNFDLRPGVIVRDLDLARPIYFKTASYGHFTNQENTWEIPRKLKF

GO term prediction

Biological Process

GO:0006556 S-adenosylmethionine biosynthetic process

Molecular Function

GO:0004478 methionine adenosyltransferase activity
GO:0005524 ATP binding

Cellular Component

None predicted.