Protein

MCA_03944_1

Length
718 amino acids


Gene name: ITR2

Description: Myo-inositol transporter 2; member of the sugar transporter superfamily

Browser: contigC:1577293-1579450-

RNA-seq: read pairs 2462, FPKM 42.3, percentile rank 61.6% (100% = highest expression)

Protein function

Annotation:ITR2Myo-inositol transporter 2; member of the sugar transporter superfamily
KEGG:K08150SLC2A13 MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
EGGNOG:0PG6BITR2myo-inositol transporter
SGD closest match:S000005463ITR2Myo-inositol transporter 2
CGD closest match:CAL0000201160ITR1Myo-inositol transporter

Protein alignments

%idAln lengthE-value
A0A060T980_BLAAD55.01%5490.0ARAD1D13442p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D13442g PE=3 SV=1
A0A1E4THV4_9ASCO50.00%5481e-175Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26166 PE=3 SV=1
UniRef50_A0A1X7R89548.29%5551e-157Similar to Saccharomyces cerevisiae YDR497C ITR1 Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7R895_9SACH
ITR2_YEAST47.01%5513e-161Myo-inositol transporter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ITR2 PE=1 SV=2
A0A167C8S8_9ASCO43.04%5602e-141Myo-inositol transporter ITR2 OS=Sugiyamaella lignohabitans GN=ITR2 PE=3 SV=1
MIA_03178_165.70%2422e-102MIA_03178_1
A0A0J9X2M9_GEOCN62.75%2552e-98Similar to Saccharomyces cerevisiae YDR497C ITR1 Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p OS=Geotrichum candidum GN=BN980_GECA01s04091g PE=3 SV=1
Q6C0K5_YARLI61.63%2452e-98YALI0F23903p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23903g PE=3 SV=1
A0A1E3PKL4_9ASCO55.82%2494e-91Myo-inositol transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82794 PE=3 SV=1
A0A1D8PH98_CANAL52.99%2514e-84Myo-inositol transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ITR1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0104

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 718

Detailed signature matches

    1. PF00083 (Sugar_tr)
    1. PR00171 (SUGRTRNSPORT)
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
    1. PS00216 (SUGAR_TRAN...)
    2. PS00217 (SUGAR_TRAN...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Residue annotation

  1. putative substrate...

Protein sequence

>MCA_03944_1
MDNNKKVIPSLPAPPQADSSEPTTNNIIVDSSSEDDYEDIKPKSGESNSNRRTYEDDDDEYIDHSMSYITALHKPSDDSS
SSITKATTSSTSSKPEKKSTVLATTNELESSSFSSSSVFDKPAKDISSEEEEITIAPKDGDDDDNSSNDDGGNIYRQSDL
ERKQKMNSFMLTLTFLTSVCGFLFGYDTGYISGALVVISDSNDLNRPNGILTSGNKEFITSATSLGALLFAIVGGVLADQ
FGRKIVVSFGNVLFIAGALIQVFANNLWTMIAGRFVMGLGVGLASLIAPLYISEMAPSRFRGRLVIINVLAITGGQLVAY
ALSVGLVKIDKYGWRILVGLSCVPAIIQMVLFLFYMPETPRYLVIQNKIEEARKGLRKVYGGSDEDEIEKKLQELILHHR
KEEQEINNSRMKARRAKRMMKQKNRVTAAGGARGDHSVDNDSFDDNDSDSMENATWRQRLSEWWFRTWLPFYELHTVPSN
FRALVITCGLQGIQQFSGFNSLMYFSGTIFQSVGFKNPILTSLIVSGTNFVFTMVAFCIIDKVGRRKILLCTIWGMAAAL
VVNAVAFHYVDFVHDVGQGGHENEGNQQSAWSKIILVAMLVYVAFYALGIGNIPWQQGEMFGSTRTRSAGSCLATTTNWS
GSLVISSTFLTMLKQMTPTGTFAFFAGLCVCGQVFVYFLYPETAGLNLEQVQGLLKDGFNVKESVRLNKERMKNDKQV

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane