MCA_03944_1
Gene name: ITR2
Description: Myo-inositol transporter 2; member of the sugar transporter superfamily
Browser: contigC:1577293-1579450-
RNA-seq: read pairs 2462, FPKM 42.3, percentile rank 61.6% (100% = highest expression)
Protein function
Annotation: | ITR2 | Myo-inositol transporter 2; member of the sugar transporter superfamily | |
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KEGG: | K08150 | SLC2A13 | MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13 |
EGGNOG: | 0PG6B | ITR2 | myo-inositol transporter |
SGD closest match: | S000005463 | ITR2 | Myo-inositol transporter 2 |
CGD closest match: | CAL0000201160 | ITR1 | Myo-inositol transporter |
Protein alignments
%id | Aln length | E-value | ||
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A0A060T980_BLAAD | 55.01% | 549 | 0.0 | ARAD1D13442p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D13442g PE=3 SV=1 |
A0A1E4THV4_9ASCO | 50.00% | 548 | 1e-175 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26166 PE=3 SV=1 |
UniRef50_A0A1X7R895 | 48.29% | 555 | 1e-157 | Similar to Saccharomyces cerevisiae YDR497C ITR1 Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7R895_9SACH |
ITR2_YEAST | 47.01% | 551 | 3e-161 | Myo-inositol transporter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ITR2 PE=1 SV=2 |
A0A167C8S8_9ASCO | 43.04% | 560 | 2e-141 | Myo-inositol transporter ITR2 OS=Sugiyamaella lignohabitans GN=ITR2 PE=3 SV=1 |
MIA_03178_1 | 65.70% | 242 | 2e-102 | MIA_03178_1 |
A0A0J9X2M9_GEOCN | 62.75% | 255 | 2e-98 | Similar to Saccharomyces cerevisiae YDR497C ITR1 Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p OS=Geotrichum candidum GN=BN980_GECA01s04091g PE=3 SV=1 |
Q6C0K5_YARLI | 61.63% | 245 | 2e-98 | YALI0F23903p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23903g PE=3 SV=1 |
A0A1E3PKL4_9ASCO | 55.82% | 249 | 4e-91 | Myo-inositol transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82794 PE=3 SV=1 |
A0A1D8PH98_CANAL | 52.99% | 251 | 4e-84 | Myo-inositol transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ITR1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0104
Protein family membership
- Major facilitator, sugar transporter-like (IPR005828)
- Sugar/inositol transporter (IPR003663)
Domains and repeats
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Domain
Detailed signature matches
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CYTOPLASMIC_D... (C...)
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-
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
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mobidb-lite (disord...)
Residue annotation
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putative substrate...
Protein sequence
>MCA_03944_1 MDNNKKVIPSLPAPPQADSSEPTTNNIIVDSSSEDDYEDIKPKSGESNSNRRTYEDDDDEYIDHSMSYITALHKPSDDSS SSITKATTSSTSSKPEKKSTVLATTNELESSSFSSSSVFDKPAKDISSEEEEITIAPKDGDDDDNSSNDDGGNIYRQSDL ERKQKMNSFMLTLTFLTSVCGFLFGYDTGYISGALVVISDSNDLNRPNGILTSGNKEFITSATSLGALLFAIVGGVLADQ FGRKIVVSFGNVLFIAGALIQVFANNLWTMIAGRFVMGLGVGLASLIAPLYISEMAPSRFRGRLVIINVLAITGGQLVAY ALSVGLVKIDKYGWRILVGLSCVPAIIQMVLFLFYMPETPRYLVIQNKIEEARKGLRKVYGGSDEDEIEKKLQELILHHR KEEQEINNSRMKARRAKRMMKQKNRVTAAGGARGDHSVDNDSFDDNDSDSMENATWRQRLSEWWFRTWLPFYELHTVPSN FRALVITCGLQGIQQFSGFNSLMYFSGTIFQSVGFKNPILTSLIVSGTNFVFTMVAFCIIDKVGRRKILLCTIWGMAAAL VVNAVAFHYVDFVHDVGQGGHENEGNQQSAWSKIILVAMLVYVAFYALGIGNIPWQQGEMFGSTRTRSAGSCLATTTNWS GSLVISSTFLTMLKQMTPTGTFAFFAGLCVCGQVFVYFLYPETAGLNLEQVQGLLKDGFNVKESVRLNKERMKNDKQV
GO term prediction
Biological Process
GO:0055085 transmembrane transport
Molecular Function
GO:0005215 transporter activity
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane