Protein
MCA_03882_1
Length
482 amino acids
Gene name: ROT1
Description: Protein ROT1; Molecular chaperone involved in protein folding in ER
Browser: contigC:1392963-1394569+
RNA-seq: read pairs 5037, FPKM 128.9, percentile rank 82.8% (100% = highest expression)
Protein function
| Annotation: | ROT1 | Protein ROT1; Molecular chaperone involved in protein folding in ER | |
|---|---|---|---|
| EGGNOG: | 0PFUS | ROT1 | Required for normal levels of the cell wall 1,6-beta- glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies |
| SGD closest match: | S000004813 | ROT1 | Protein ROT1 |
| CGD closest match: | CAL0000184365 | ROT1 | Protein ROT1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03255_1 | 73.50% | 234 | 2e-104 | MIA_03255_1 |
| A0A0J9XHF6_GEOCN | 66.67% | 237 | 4e-98 | Similar to Saccharomyces cerevisiae YMR200W ROT1 Molecular chaperone involved in protein folding in the ER OS=Geotrichum candidum GN=BN980_GECA17s00939g PE=4 SV=1 |
| A0A060T5E9_BLAAD | 62.16% | 222 | 2e-85 | Protein ROT1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10604g PE=3 SV=1 |
| ROT1_YARLI | 58.80% | 233 | 3e-81 | Protein ROT1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ROT1 PE=3 SV=1 |
| UniRef50_A0A1Q2YKQ3 | 57.83% | 230 | 7e-74 | Uncharacterized protein n=1 Tax=Pichia membranifaciens TaxID=4926 RepID=A0A1Q2YKQ3_9ASCO |
| A0A1E3PIV1_9ASCO | 58.08% | 229 | 1e-77 | Protein ROT1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70724 PE=3 SV=1 |
| ROT1_YEAST | 58.30% | 223 | 2e-74 | Protein ROT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ROT1 PE=1 SV=1 |
| ROT1_CANAL | 51.09% | 229 | 5e-64 | Protein ROT1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ROT1 PE=3 SV=1 |
| A0A1E4TKI6_9ASCO | 52.04% | 221 | 1e-60 | Protein ROT1 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_851 PE=3 SV=1 |
| A0A161HF78_9ASCO | 56.55% | 168 | 8e-46 | Rot1p OS=Sugiyamaella lignohabitans GN=ROT1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.5551
Predicted cleavage: 115
Protein family membership
- Protein Rot1 (IPR019623)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF10681 (Rot1)
-
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
-
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_03882_1 MLMKRSIFLIVLLFSLIYLRAVDSQAVANPANPPVAGAGAGAAANPANPGAGAAANPANPGAGAGAAANPANQGAGAAAN PPANAPAAANPANPPAAGAGAAANPGAANQANRPAAGAGAAANPANQGAGAAANPANQGAGAAANPANQGAGAAANPPAN APAAANPANPPAAGAGAAANPGAANQANPPAANPQANVPVANPPAAANPPANAPAAGAGAGAAVGAGVGAAAANPAASAS SVPEANSPPTSDSSIIGSVEFEGTWTSKSNAVFTGPDFYDPVDELLIEPALPGMSFSFTADGFWEQATYQVSGNARDHHC PSAVLIFQHGTWKKLDNDTLILEPFKVDGRQLLSDPCKSKTSVYSRYNQTIIFQKWAVYVDPYHGRYRLDLYQFDGKPLP PLYLTYKPPMMLPTITMNPTATGASGTPDPTASNASLRKKIRRSLENRNRTPAVKKRSTNYDMIWWTGVILMAVGATGFI II
GO term prediction
Biological Process
GO:0006458 'de novo' protein folding
Molecular Function
None predicted.
Cellular Component
GO:0005783 endoplasmic reticulum