Protein

MCA_03877_1

Length
240 amino acids

Gene name: TPI1

Description: Triosephosphate isomerase

Browser: contigC:1377844-1378567-

RNA-seq: read pairs 38067, FPKM 1951.7, percentile rank 97.8% (100% = highest expression)

Protein function

Annotation:TPI1Triosephosphate isomerase
KEGG:K01803TPI triosephosphate isomerase (TIM) [EC:5.3.1.1]
EGGNOG:0PGYITPI1Triose-phosphate isomerase
SGD closest match:S000002457TPI1Triosephosphate isomerase
CGD closest match:CAL0000173961TPI1Triosephosphate isomerase

Protein alignments

%idAln lengthE-value
MIA_04374_182.92%2407e-145MIA_04374_1
A0A0J9XIM2_GEOCN75.31%2399e-129Triosephosphate isomerase OS=Geotrichum candidum GN=BN980_GECA21s00923g PE=3 SV=1
A0A1E3PK01_9ASCO70.71%2396e-123Triosephosphate isomerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82735 PE=3 SV=1
A0A1E4TGF7_9ASCO67.36%2395e-119Triosephosphate isomerase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44489 PE=3 SV=1
TPIS_YARLI70.29%2393e-118Triosephosphate isomerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TPI1 PE=3 SV=1
A0A060TBJ6_BLAAD64.85%2392e-115Triosephosphate isomerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32340g PE=3 SV=1
A0A167D613_9ASCO65.55%2386e-114Triosephosphate isomerase OS=Sugiyamaella lignohabitans GN=TPI1 PE=3 SV=1
TPIS_CANAL64.46%2424e-108Triosephosphate isomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TPI1 PE=1 SV=3
UniRef50_Q9P94064.46%2429e-105Triosephosphate isomerase n=507 Tax=Eukaryota TaxID=2759 RepID=TPIS_CANAL
TPIS_YEAST63.60%2392e-106Triosephosphate isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPI1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3812

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 240

Detailed signature matches

  1. Family IPR000652
    Triosephosphate isomerase
    1. PF00121 (TIM)
    2. PS51440 (TIM_2)
    3. cd00311 (TIM)
    4. SSF51351 (Triosepho...)
    5. TIGR00419
  2. Family IPR022896
    Triosephosphate isomerase, bacterial/eukaryotic
    1. MF_00147_B (TIM_B)
  3. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  4. SITE IPR020861
    Triosephosphate isomerase, active site
    1. PS00171 (TIM_1)

Residue annotation

  1. dimer interface cd...
  2. catalytic triad cd...
  3. substrate binding ...

Protein sequence

>MCA_03877_1
MNGSLESIKAIVDGLNKASIPSNVEVVISPPFPYLKYTKDALAADSKVEVAAQNSFDRGNGAFTGEVSVAQIKDVGSTWV
ILGHSERRTIIKESDEFIADKTKYALDNGLKVILCIGETLEERKSNETLNVCNRQIDAVIAKVSDPKDWANIVIAYEPVW
AIGTGMAATPDDAQEVHSKIRAHLKEKLGAEVADSVRILYGGSVNGKNATTFNDKPDIDGYLVGGASLKPEFLDIIKSRA

GO term prediction

Biological Process

GO:0006096 glycolytic process
GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004807 triose-phosphate isomerase activity

Cellular Component

None predicted.