Protein

MCA_03855_1

Length
847 amino acids

Gene name: LSG1

Description: Large subunit GTPase 1; Putative GTPase involved in 60S ribosomal subunit biogenesis

Browser: contigC:1308533-1311148+

RNA-seq: read pairs 2823, FPKM 41.1, percentile rank 60.9% (100% = highest expression)

Protein function

Annotation:LSG1Large subunit GTPase 1; Putative GTPase involved in 60S ribosomal subunit biogenesis
KEGG:K14539LSG1 large subunit GTPase 1 [EC:3.6.1.-]
EGGNOG:0PFXGFG07194.1(GTP)-binding protein
SGD closest match:S000003067LSG1Large subunit GTPase 1
CGD closest match:CAL0000183488orf19.3463Putative GTPase

Protein alignments

%idAln lengthE-value
MIA_00769_162.30%3825e-144MIA_00769_1
A0A0J9X9R1_GEOCN65.36%3061e-119Similar to Saccharomyces cerevisiae YGL099W LSG1 Putative GTPase involved in 60S ribosomal subunit biogenesis OS=Geotrichum candidum GN=BN980_GECA06s02144g PE=4 SV=1
UniRef50_A0A0J9X9R165.36%3062e-116Similar to Saccharomyces cerevisiae YGL099W LSG1 Putative GTPase involved in 60S ribosomal subunit biogenesis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9R1_GEOCN
A0A167FC75_9ASCO58.51%2821e-102Putative GTPase LSG1 OS=Sugiyamaella lignohabitans GN=LSG1 PE=4 SV=1
A0A060T9N5_BLAAD59.64%2808e-101ARAD1D13244p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D13244g PE=4 SV=1
A0A1E3PPD6_9ASCO60.66%2723e-97p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40344 PE=4 SV=1
Q6CB48_YARLI57.82%2758e-94YALI0C21956p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C21956g PE=4 SV=1
Q59S77_CANAL54.96%2822e-87Putative GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3463 PE=4 SV=1
LSG1_YEAST53.51%2712e-83Large subunit GTPase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LSG1 PE=1 SV=1
A0A1E4TI62_9ASCO57.34%2181e-77Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11754 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9850
Predicted cleavage: 39

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 847

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR030378
    Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
    1. PS51721 (G_CP)
  3. Domain IPR006073
    GTP binding domain
    1. PF01926 (MMR_HSR1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.12...
  3. cd01857 (HSR1_MMR1)
  4. mobidb-lite (disord...)

Residue annotation

  1. G4 box cd01857
  2. GTP/Mg2+ binding s...
  3. G5 box cd01857
  4. G1 box cd01857
  5. Switch I region cd...
  6. G2 box cd01857
  7. G3 box cd01857
  8. Switch II region c...

Protein sequence

>MCA_03855_1
MVKRYGAWKAPKAGSKKRANARNPTGLGRALQNSSKKAGKPQGFIDGQGNFRYTTDINDEGKPRPSDNSEEPGWVKLRSV
TQENALDEFLSTAELAAKDFTADRYNSVKIISQPSASSVSGLPISSFTAHNPYLLSPQEREEIEALQRINRGKLTVPRRP
RWEKGITAQELDRMEKDNFLEWRRQLAQLQDNQDLLMTPFERNIEVWRQLWRVIERSDLVVQIVDARNPLFFRSEDLETY
VKEYDNGIKHNLLLINKADLLSPTQRQAWANYFHKNGIRYAFFSAFTALQEQEADIAKQQQEEEERKRQLEEEEDDSSGE
EDEEESEEEEDDDDNQSETKKEQEKTQTTEKESNEQTPVREILKNNPIHILSVNQLEELFLTEVPPKQREEEEEEEEEDT
SSRKNGNHKKPKKFNKTALNIGLVGYPNVGKSSTINALIGAKKVSVSATPGKTKHFQTIQLSKDVTLCDCPGLVFPNFSN
TNAELVCNGVLPIDQLREFTGPTDLVTQRIPKFFLEAIYGITIYIKPIPDGGSGIPTAQELLYAYARARGFMRAGKGTPD
ESRAARYILKDYVTAKLLYCHPPPDWKPSTPDELLTNEKLRQLPAFASMSPEEIAGRAFNSQLYSLKSLPEARRTQILLA
IAKKRYGEKATLQTLLQETQKEKAYHEEGTTVVNNKKPEKEYDSEDDLSDEEDFEDDDEDYDEEDLDEEELNKKKPAANY
QKITLSDIIDGINLAEELESLSFSQHISFSQMKNSKNKSQLSAMPTANSQGVVSASANFDNDFFQTSALLGHRNLPFHQQ
QMSKKGGKKGAKIAELKGNTSSKSKKAAKKKRRAGAGSGTNLYSDLY

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.