Protein

MCA_03846_1

Length
573 amino acids

Gene name: NDE1A

Description: External NADH-ubiquinone oxidoreductase 1, mitochondrial

Browser: contigC:1273720-1275442+

RNA-seq: read pairs 16515, FPKM 355.5, percentile rank 92.8% (100% = highest expression)

Protein function

Annotation:NDE1AExternal NADH-ubiquinone oxidoreductase 1, mitochondrial
KEGG:K17871ndh1 NADH:ubiquinone reductase (non-electrogenic) [EC:1.6.5.9]
EGGNOG:0PIYANDE1NADH dehydrogenase
SGD closest match:S000004753NDE1External NADH-ubiquinone oxidoreductase 1, mitochondrial
CGD closest match:CAL0000200307NDE1NADH-ubiquinone reductase (H(+)-translocating)

Protein alignments

%idAln lengthE-value
MIA_03206_180.82%5110.0MIA_03206_1
A0A0J9X410_GEOCN77.45%5100.0Similar to Saccharomyces cerevisiae YMR145C NDE1 Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH OS=Geotrichum candidum GN=BN980_GECA02s06192g PE=4 SV=1
A0A060TAJ6_BLAAD70.99%5170.0ARAD1D20086p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20086g PE=4 SV=1
A0A167D6R4_9ASCO74.22%5120.0NADH-ubiquinone reductase (H(+)-translocating) NDE1 OS=Sugiyamaella lignohabitans GN=NDE1 PE=4 SV=1
NDH2_YARLI67.83%5160.0External alternative NADH-ubiquinone oxidoreductase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NDH2 PE=1 SV=1
UniRef50_F2Z69967.83%5160.0External alternative NADH-ubiquinone oxidoreductase, mitochondrial n=403 Tax=Eukaryota TaxID=2759 RepID=NDH2_YARLI
A0A1E4TAG6_9ASCO63.60%5220.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_128582 PE=4 SV=1
A0A1E3PS28_9ASCO61.45%5110.0FAD/NAD(P)-binding domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81254 PE=4 SV=1
Q5AEC9_CANAL50.93%5367e-171NADH-ubiquinone reductase (H(+)-translocating) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NDE1 PE=4 SV=1
NDH1_YEAST49.00%5023e-143External NADH-ubiquinone oxidoreductase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NDE1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9979
Predicted cleavage: 55

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 573

Detailed signature matches

  1. Domain IPR023753
    FAD/NAD(P)-binding domain
    1. PF07992 (Pyr_redox_2)
    2. G3DSA:3.50.50.60
    3. SSF51905 (FAD/NAD(P...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. PR00368 (FADPNR)
  5. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_03846_1
MLPRSLNCSRQLARPFLGSHSLAAAPLFTKTSNTAARVALLSSARQFSSFSPRFSSVTPPPPAPKKKWGFWKTLWRVTYV
SFFAAVGYTAYTIYEIRNPKDQKPADPSKKTLVILGTGWGSVSLLKKIDASNYNIIVVSPRNFFLFTPLLPSCTTGTVEH
RSIMEPVRNIIRMKESAVTYYEAEATSIDYDNHKVIIKDAVGNAEKTLDYDYLVVGVGAQNSTFGIPGVQEHACFLKEIP
DAQKIRKKIMDCIESASFMSDEKDRKKILHTVVVGGGPTGVEFAAELQDFFEEDLRKWIPEVAKDFKVTLVEALPNVLPS
FSKQLIQYTENTFKAEQITVLTKTMVKKVDDNFIYAEASKPDGTKELLELPYGLLVWATGNSVRPVVRDILTRNPAQRNS
RRGLLVNEYLVVEGTEDVWALGDCTATKYAPTAQVAAQQGVYLAGLFNQLAKAEELRQEIEKLQALSKSVTNDPDRKAVL
AESEAKQRKLRRTESLLPFEYSHQGSLAYIGSDRAVADLKFWGEASNYASGGRLTYLFWRSAYISMVFSARNRLLVVFDW
IKVKLFGRDVSRE

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.