Protein

MCA_03814_1

Length
337 amino acids

Gene name: TDH1

Description: Glyceraldehyde-3-phosphate dehydrogenase

Browser: contigC:1160071-1161173+

RNA-seq: read pairs 646756, FPKM 23643.1, percentile rank 100.0% (100% = highest expression)

Protein function

Annotation:TDH1Glyceraldehyde-3-phosphate dehydrogenase
KEGG:K00134GAPDH glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
EGGNOG:0PF9KGPDglyceraldehyde-3-phosphate dehydrogenase
SGD closest match:S000003588TDH1Glyceraldehyde-3-phosphate dehydrogenase 1
CGD closest match:CAL0000197744TDH3Glyceraldehyde-3-phosphate dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_05226_188.99%3360.0MIA_05226_1
A0A0J9XLL3_GEOCN84.73%3340.0Glyceraldehyde-3-phosphate dehydrogenase OS=Geotrichum candidum GN=BN980_GECA32s01660g PE=3 SV=1
A0A1E3PM77_9ASCO81.90%3370.0Glyceraldehyde-3-phosphate dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23250 PE=3 SV=1
G3P_YARLI81.95%3380.0Glyceraldehyde-3-phosphate dehydrogenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=GPD PE=3 SV=1
A0A060T9D2_BLAAD79.10%3350.0Glyceraldehyde-3-phosphate dehydrogenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D16896g PE=3 SV=1
A0A0A0WGN4_9ASCO79.23%3370.0Glyceraldehyde-3-phosphate dehydrogenase OS=Sugiyamaella lignohabitans GN=TDH3 PE=3 SV=1
Q5ADM7_CANAL75.82%3350.0Glyceraldehyde-3-phosphate dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TDH3 PE=3 SV=1
A0A1E4TG95_9ASCO75.60%3360.0Glyceraldehyde-3-phosphate dehydrogenase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2427 PE=3 SV=1
UniRef50_C7YPH873.87%3338e-179Glyceraldehyde-3-phosphate dehydrogenase n=83 Tax=cellular organisms TaxID=131567 RepID=C7YPH8_NECH7
G3P1_YEAST72.04%3292e-177Glyceraldehyde-3-phosphate dehydrogenase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TDH1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9008

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 337

Detailed signature matches

  1. Family IPR020831
    Glyceraldehyde/Erythrose phosphate dehydrogenase family
    1. PR00078 (G3PDHDRGNASE)
    2. PIRSF000149 (GAPDH)
  2. Family IPR006424
    Glyceraldehyde-3-phosphate dehydrogenase, type I
    1. TIGR01534
  3. Domain IPR020828
    Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
    1. PF00044 (Gp_dh_N)
    2. SM00846 (gp_dh_n_7)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR020829
    Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
    1. PF02800 (Gp_dh_C)
  6. SITE IPR020830
    Glyceraldehyde 3-phosphate dehydrogenase, active site
    1. PS00071 (GAPDH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.36...
  2. G3DSA:3.40.50...
  3. SSF55347 (Glycerald...)

Protein sequence

>MCA_03814_1
MVTKVGINGFGRIGRIVLRNALKNPDVEVVAFNDPFITADYAAYMFKFDSTHGKFNGSVESKDGALYINDKKISVFGERD
PSSIPWGSVGADYVVESTGVFTTTEKASAHLKGGAKKVVISAPSADAPMFVVGVNLDKYTPDLKVVSNASCTTNCLAPLA
KVVNDKFGIIEGLMTTVHSITATQKTVDGPSHKDWRGGRTAGDNIIPSSTGAAKAVGKVIPELNGKLTGLSLRVPTSDVS
VVDLTVRLEKAVTYDDIKAAIKAESEGELKGVLGYTEEAVVSTDFKGDTHSSIFDASAGILLNEHFVKLISWYDNEYGYS
ARVVDLLVYISKVDASA

GO term prediction

Biological Process

GO:0006006 glucose metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding

Cellular Component

None predicted.