MCA_03793_1

Protein

Length

263 amino acids

Gene name: RVS161

Description: Reduced viability upon starvation protein 161

Browser: contigC:1107946-1108829+

RNA-seq: read pairs 5654, FPKM 264.6, percentile rank 90.9% (100% = highest expression)

Protein function

Annotation:		RVS161	Reduced viability upon starvation protein 161
KEGG:	K20120	BIN3	bridging integrator 3
EGGNOG:	0QE92	RVS161	Reduced viability upon starvation protein 161
SGD closest match:	S000000602	RVS161	Reduced viability upon starvation protein 161
CGD closest match:	CAL0000193274	RVS161	Regulator of cytoskeleton and endocytosis RVS161

Protein alignments

	%id	Aln length	E-value
MIA_05107_1	90.11%	263	0.0	MIA_05107_1
A0A0J9XDR9_GEOCN	87.36%	261	5e-175	Similar to Saccharomyces cerevisiae YCR009C RVS161 Amphiphysin-like lipid raft protein OS=Geotrichum candidum GN=BN980_GECA12s00593g PE=4 SV=1
A0A167CQU7_9ASCO	86.21%	261	2e-174	Amphiphysin-like protein RVS161 OS=Sugiyamaella lignohabitans GN=RVS161 PE=4 SV=1
A0A060TBV2_BLAAD	82.82%	262	2e-169	ARAD1D34892p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D34892g PE=4 SV=1
Q6CCM8_YARLI	83.59%	262	1e-168	YALI0C08118p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C08118g PE=4 SV=1
A0A1E3PNZ8_9ASCO	81.23%	261	6e-164	BAR-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45341 PE=4 SV=1
A0A1E4TF52_9ASCO	75.19%	262	1e-152	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106303 PE=4 SV=1
UniRef50_F9XHA0	71.48%	263	1e-139	Uncharacterized protein n=49 Tax=Ascomycota TaxID=4890 RepID=F9XHA0_ZYMTI
RV161_YEAST	63.02%	265	1e-122	Reduced viability upon starvation protein 161 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RVS161 PE=1 SV=1
RV161_CANAL	60.38%	265	9e-117	Regulator of cytoskeleton and endocytosis RVS161 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RVS161 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7448
Predicted cleavage: 14

Protein family membership

None predicted.

Domains and repeats

Domain
5 - 237
Arfaptin homology (AH) domain/BAR domain (IPR027267)
BAR domain (IPR004148)

1 50 100 150 200 263

Detailed signature matches

IPR027267

Arfaptin homology (AH) domain/BAR domain
1. SSF103657 (BAR/IMD ...)
  
  20 - 234
  
  SUPERFAMILY
  SSF103657 (BAR/IMD domain-like)
IPR004148

BAR domain
1. PS51021 (BAR)
  
  17 - 237
  
  PROSITE profiles
  PS51021 (BAR)
2. SM00721 (5bar)
  
  5 - 230
  
  SMART
  SM00721 (5bar)
3. PF03114 (BAR)
  
  6 - 229
  
  Pfam
  PF03114 (BAR)

no IPR

Unintegrated signatures

Coil

32 - 52

COILS
Coil (Coil)

163 - 183

COILS
Coil (Coil)
G3DSA:1.20.12...

13 - 236

GENE3D
G3DSA:1.20.1270.60 (G3DSA:1.20.1270.60)
cd07591 (BAR_Rvs161p)

20 - 241

CDD
cd07591 (BAR_Rvs161p)

Residue annotation

dimer interface cd...

38R

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

41T

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

42M

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

46C

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

48K

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

49L

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

52E

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

53A

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

55G

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

56Y

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

66S

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

67Q

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

69R

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

70I

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

73T

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

74I

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

76A

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

77F

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

80D

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

92L

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

95V

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

96Q

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

189P

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

192I

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

193D

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

195R

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

200D

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

203F

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

204E

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

206L

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

207V

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

210Q

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

211L

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

214C

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

215T

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

217S

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

218Y

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

221L

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

222A

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

224V

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

225Q

dimer interface
38R, 41T, 42M, 46C, 48K, 49L, 52E, 53A, 55G, 56Y, 66S, 67Q, 69R, 70I, 73T, 74I, 76A, 77F, 80D, 92L, 95V, 96Q, 189P, 192I, 193D, 195R, 200D, 203F, 204E, 206L, 207V, 210Q, 211L, 214C, 215T, 217S, 218Y, 221L, 222A, 224V, 225Q
CDD
cd07591 (BAR_Rvs161p)

Protein sequence

>MCA_03793_1
MSWNGFKKAINRAGTSVMMKTGQVEKTVDKEFEVEERRYRTMETACNKLQKEAKGYLDSLRAMTASQTRIAETIDAFYGD
AGTRDGVSKHYLTAVQELDTETVKALDGPFRETVLEPITRFCSYFSDVNEAIKKRNHKMMDYDALRAKVKRLIEKPSDDA
TKLPRMEKDLQFAKDVYEQLNNQLTTELPKLIDLRVPYLDPSFEALVKIQLRFCTESYTRLAQVQQYLDASTREEYANGQ
LDNKVEEVLQSMKELSITSLGTV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features