MCA_03782_1

Protein

Length

569 amino acids

Gene name: MAL11

Description: High-affinity maltose transporter (alpha-glucoside transporter)

Browser: contigC:1068507-1070217+

RNA-seq: read pairs 943, FPKM 20.4, percentile rank 42.0% (100% = highest expression)

Protein function

Annotation:		MAL11	High-affinity maltose transporter (alpha-glucoside transporter)
KEGG:	K08141	MAL	MFS transporter, SP family, general alpha glucoside:H+ symporter
EGGNOG:	0PF97		Maltose permease
SGD closest match:	S000003521	MAL11	General alpha-glucoside permease
CGD closest match:	CAL0000184818	MAL31	Maltose permease

Protein alignments

	%id	Aln length	E-value
MIA_05170_1	53.44%	494	1e-172	MIA_05170_1
UniRef50_A0A1N6MC50	41.51%	518	9e-122	Putative sugar porter n=1 Tax=Candida hispaniensis TaxID=312227 RepID=A0A1N6MC50_9ASCO
A0A060TAD9_BLAAD	42.17%	517	2e-119	ARAD1D18106p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D18106g PE=3 SV=1
Q6CH11_YARLI	39.29%	509	5e-102	YALI0A14212p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A14212g PE=3 SV=2
MAL11_YEAST	34.23%	555	3e-95	General alpha-glucoside permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAL11 PE=1 SV=1
Q5AK39_CANAL	34.55%	521	2e-90	Maltose permease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MAL31 PE=3 SV=1
A0A167E5Q6_9ASCO	40.39%	406	7e-85	Mal31p OS=Sugiyamaella lignohabitans GN=MAL31 PE=3 SV=1
A0A1E3PR23_9ASCO	26.93%	401	1e-27	General substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80878 PE=3 SV=1
A0A0J9XGJ5_GEOCN	25.67%	487	2e-24	Similar to Saccharomyces cerevisiae YHR096C HXT5 Hexose transporter with moderate affinity for glucose OS=Geotrichum candidum GN=BN980_GECA15s00725g PE=3 SV=1
A0A1E4TA60_9ASCO	26.04%	407	3e-20	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_126349 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0314

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)
- Sugar/inositol transporter (IPR003663)

Domains and repeats

Domain
81 - 538
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 569

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  82 - 540
  
  Pfam
  PF00083 (Sugar_tr)
IPR003663

Sugar/inositol transporter
1. TIGR00879
  
  31 - 536
  
  TIGRFAMs
  TIGR00879 (TIGR00879)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  81 - 529
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  317 - 538
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  84 - 283
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  83 - 523
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

524 - 569

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 77

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

205 - 215

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

269 - 339

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

393 - 403

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

152 - 157

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

461 - 471

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

313 - 552

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

64 - 285

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

362 - 372

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

95 - 125

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

240 - 244

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

177 - 181

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

422 - 432

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

495 - 505

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

158 - 177

TMHMM
TMhelix (TMhelix)

341 - 363

TMHMM
TMhelix (TMhelix)

373 - 395

TMHMM
TMhelix (TMhelix)

402 - 424

TMHMM
TMhelix (TMhelix)

474 - 496

TMHMM
TMhelix (TMhelix)

506 - 523

TMHMM
TMhelix (TMhelix)

182 - 204

TMHMM
TMhelix (TMhelix)

439 - 461

TMHMM
TMhelix (TMhelix)

254 - 276

TMHMM
TMhelix (TMhelix)

129 - 151

TMHMM
TMhelix (TMhelix)

217 - 239

TMHMM
TMhelix (TMhelix)

78 - 100

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

126 - 151

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

78 - 94

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

506 - 523

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

245 - 268

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

404 - 421

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

216 - 239

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

182 - 204

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

433 - 460

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

373 - 392

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

340 - 361

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

158 - 176

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

472 - 494

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

96G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

99T

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

100G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

101G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

103L

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

104A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

132G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

135I

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

136C

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

139R

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

143A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

144L

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

146V

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

147G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

193W

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

194G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

197N

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

198T

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

201S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

202T

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

205S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

217T

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

218S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

221N

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

222L

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

228Q

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

349A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

352G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

353D

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

356T

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

357G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

360A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

373S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

377A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

381A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

384S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

388T

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

446L

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

449N

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

450L

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

453G

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

457L

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

458I

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

461S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

472S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

473I

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

476A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

477M

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

480Y

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

481A

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

484S

putative substrate translocation pore
96G, 99T, 100G, 101G, 103L, 104A, 132G, 135I, 136C, 139R, 143A, 144L, 146V, 147G, 193W, 194G, 197N, 198T, 201S, 202T, 205S, 217T, 218S, 221N, 222L, 228Q, 349A, 352G, 353D, 356T, 357G, 360A, 373S, 377A, 381A, 384S, 388T, 446L, 449N, 450L, 453G, 457L, 458I, 461S, 472S, 473I, 476A, 477M, 480Y, 481A, 484S
CDD
cd06174 (MFS)

Protein sequence

>MCA_03782_1
MHFRKDKSQSTKLSTISDSATTLVSELYLQDKHNQSDKKNDIQTEISSILNDEDTGSKATDFEHSLTTFRALGLYKKAVF
WSVVVSIILIMDGYDGTLTGGLLAQKAFQEAYGERLPSGNYNISTAWQLTVGLVICVSRIIGALGVGFFISKWGCKKTLI
CSLFFVIAFLFIEFFAQNMGTLTIGAALANIIWGGFNTLASTYASEVCPVALRGILTSYINLAWGIGQLISQCVLNGFVE
SSSHWSYRIPFAIQWVWPVLLLVLLPFAPESPWWLVRRDRLGDARKALEKLTSFKESESYLIDNQLFMIIETDRKERENN
TEEVGWKDCFKGIDARRTEIGCMAWVVQAFSGDNLTGYAAYFFELAGLDKNQSFKLALGLAVISVVGTIISWSFTDKFGR
RSTYLVGISFIVIFLFLMGIFDFPKKGPNFQTFAWIQSILLLLISLTFNLTLGPVALIVVSEVSAIRLREKSIALAMSSY
AVCSLVLQVVVPLMINPGAGNWSGKIGFFFGGLSVISFIWTYFRLPEMSGRTFAEIDHMFELKLPARAFKKYNFEHEKEV
KSQLDDVSD

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features