Protein

MCA_03685_1

Length
626 amino acids

Gene name: TRM44

Description: tRNA (uracil-O(2)-)-methyltransferase

Browser: contigC:768760-770641+

RNA-seq: read pairs 600, FPKM 11.8, percentile rank 28.9% (100% = highest expression)

Protein function

Annotation:TRM44tRNA (uracil-O(2)-)-methyltransferase
KEGG:K15447TRM44 tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
EGGNOG:0PIV3TRM44adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase (By similarity)
SGD closest match:S000005951TRM44tRNA (uracil-O(2)-)-methyltransferase
CGD closest match:CAL0000181781orf19.6847tRNA (Uracil) methyltransferase

Protein alignments

%idAln lengthE-value
MIA_02055_160.20%6080.0MIA_02055_1
A0A0J9XIS2_GEOCN56.38%5960.0Similar to Saccharomyces cerevisiae YPL030W TRM44 tRNA(Ser) Um(44) 2'-O-methyltransferase OS=Geotrichum candidum GN=BN980_GECA17s01286g PE=4 SV=1
UniRef50_A0A0J9XIS256.38%5960.0Similar to Saccharomyces cerevisiae YPL030W TRM44 tRNA(Ser) Um(44) 2'-O-methyltransferase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIS2_GEOCN
A0A167FJ98_9ASCO44.22%6492e-174Trm44p OS=Sugiyamaella lignohabitans GN=TRM44 PE=4 SV=1
A0A1E3PI25_9ASCO52.70%4635e-157DUF1613-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83158 PE=4 SV=1
A0A060T2T2_BLAAD44.03%5862e-153ARAD1C30954p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30954g PE=4 SV=1
TRM44_YARLI43.02%6028e-152tRNA (uracil-O(2)-)-methyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TRM44 PE=3 SV=1
A0A1D8PDB2_CANAL43.05%5973e-141tRNA (Uracil) methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6847 PE=4 SV=1
TRM44_YEAST41.91%6184e-139tRNA (uracil-O(2)-)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRM44 PE=1 SV=1
A0A1E4TDT4_9ASCO41.27%4243e-98Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_98130 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0117

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 626

Detailed signature matches

  1. Family IPR011671
    tRNA (uracil-O(2)-)-methyltransferase
    1. PF07757 (AdoMet_MTase)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Protein sequence

>MCA_03685_1
MSLNQDSCCNEHVSPAKDVRTAKNKLIAAPRQTPSQFNPIDIRKQPSILGKDWYGVYQHDVDFGATHFEKAMANILLEPN
INSTLIMRTDVISDTLADKEYTKSWLKQRGISVSDDDFTLKYRNYQKMKKNVSIPTIKNGESSSSRPKKQTTQEPVQPLD
DYQLLNLAIPENVSIDKTTMPLSHYLEDTEARHVDTELVSLERSLVRRIVPRKPLRDPVINQTCAIHTRRIDKSLSTEKA
SQQNSDRETTLPTTDQDSVLVTYIPHIKSPAECPFYLPPAKAVGILYHNYTISVHYQLYDEDRNSEVPFAELPDSDRMIR
IALHLLETPYKHSFGAKAGYKKRVYHDVVVPKVDFQNQYIHLKAKYSKEFVSNWVESTDPKKHVFEDIAIAAFIIELWSR
IYHNSKDTFTFVDVGCGNGLLVNILIQEGYKGYGIDARARKSWATYPEHVQKHLKEQVIIPKILIDETPLRTYQAEGDST
VHKYKDLLQNPAVNTAEFPENTFLIGNHSDELTVWLPLFCCPFIVIPCCSYSLNGTRTRYTPKNANSKSTYASLVDHVEE
VAQKIGWVVEKEVLRIPSTRNTALIGKTRLITPSNKTVREVLYEEGGGDGWIERVTALQTKNPRNH

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008168 methyltransferase activity

Cellular Component

None predicted.