Protein

MCA_03679_1

Length
442 amino acids

Gene name: LSC2

Description: Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

Browser: contigC:755323-756789+

RNA-seq: read pairs 33001, FPKM 920.5, percentile rank 96.4% (100% = highest expression)

Protein function

Annotation:LSC2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
KEGG:K01900LSC2 succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
EGGNOG:0PFU7PGUG_04080succinyl-CoA synthetase beta
SGD closest match:S000003476LSC2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
CGD closest match:CAL0000179299LSC2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

Protein alignments

%idAln lengthE-value
MIA_03779_185.75%4210.0MIA_03779_1
A0A0J9X9H8_GEOCN79.67%4180.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Geotrichum candidum GN=BN980_GECA06s00439g PE=3 SV=1
A0A060TDF4_BLAAD78.45%4270.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B24266g PE=3 SV=1
A0A161HKS2_9ASCO79.42%4130.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Sugiyamaella lignohabitans GN=LSC2 PE=3 SV=1
Q6CA97_YARLI77.14%4330.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D04741g PE=3 SV=2
A0A1E3PMM0_9ASCO79.67%3690.0Succinate-CoA ligase subunit beta OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45998 PE=3 SV=1
A0A1E4TK04_9ASCO69.46%4420.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82388 PE=3 SV=1
UniRef50_A0A0B8N35965.89%4310.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial n=9 Tax=leotiomyceta TaxID=716546 RepID=A0A0B8N359_9EURO
A0A1D8PTB5_CANAL67.14%4230.0Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LSC2 PE=3 SV=1
SUCB_YEAST60.85%4012e-168Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LSC2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9966
Predicted cleavage: 40

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 442

Detailed signature matches

  1. Family IPR005809
    Succinate--CoA synthetase, beta subunit
    1. TIGR01016
    2. MF_00558 (Succ_CoA_...)
    3. PIRSF001554 (SucCS_...)
  2. Domain IPR011761
    ATP-grasp fold
    1. PS50975 (ATP_GRASP)
  3. Domain IPR013650
    ATP-grasp fold, succinyl-CoA synthetase-type
    1. PF08442 (ATP-grasp_2)
  4. Domain IPR013815
    ATP-grasp fold, subdomain 1
    1. G3DSA:3.30.14...
  5. Domain IPR016102
    Succinyl-CoA synthetase-like
    1. SSF52210 (Succinyl-...)
    2. G3DSA:3.40.50...
  6. Domain IPR005811
    ATP-citrate lyase/succinyl-CoA ligase
    1. PF00549 (Ligase_CoA)
  7. SITE IPR017866
    Succinyl-CoA synthetase, beta subunit, conserved site
    1. PS01217 (SUCCINYL_C...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.47...
  2. SSF56059 (Glutathio...)

Protein sequence

>MCA_03679_1
MLSRSILSRRIANSSKAVFKQQPILKQQSRFLSLHEYRSAQILKENGVPVPPGAAATTPEEAYEVAKNLNLEDMVIKAQA
LTGGRGKGVFDSGLKGGVKLISSPFEAKMYAEQMLHHKLITKQSGPQGKDVTAVYIVQREFVRREAYLCILMDRQSQGPM
IVASSQGGMDIEGVAKETPEAIKTFPIDINKGVTDELANEVASVLGFSSKATPEAAEIVKNLYKVFSTKDATQIEINPLA
ETTQHKVYAMDAKLGFDDNADFRQQEIWSYRDLTQEDPEEVEAAQYGLNFIKLDGSIGCLVNGAGLAMATMDIIKLYGGD
PANFLDCGGGATARTIEKGFELITSDSKVTAIFVNIFGGIVRCDDIAKGLIAVTKHMNLNIPLVVRLQGTNMEAAQKLIA
DSGLKIFSYADLDEAAEKVCQLAKVVQMAREIDFNVSFELPL

GO term prediction

Biological Process

GO:0006099 tricarboxylic acid cycle
GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0046872 metal ion binding

Cellular Component

None predicted.