Protein

MCA_03663_1

Length
623 amino acids

Browser: contigC:718737-720922-

RNA-seq: read pairs 1660, FPKM 32.9, percentile rank 55.2% (100% = highest expression)

Protein function

KEGG:K18470ARHGAP1 Rho GTPase-activating protein 1
EGGNOG:0PHIXPGUG_03215RhoGAP
SGD closest match:S000003737ECM25Protein ECM25
CGD closest match:CAL0000192000ECM25Ecm25p

Protein alignments

%idAln lengthE-value
MIA_05259_165.78%3392e-155MIA_05259_1
A0A0J9XEI0_GEOCN63.69%3473e-153Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA10s02903g PE=4 SV=1
UniRef50_A0A0J9XEI063.69%3477e-150Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XEI0_GEOCN
A0A060T518_BLAAD50.45%3354e-113ARAD1C08162p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08162g PE=4 SV=1
A0A1E3PNI1_9ASCO50.15%3391e-101Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49436 PE=4 SV=1
Q6CE28_YARLI44.93%3452e-89YALI0B19052p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B19052g PE=4 SV=1
A0A167DWB1_9ASCO44.66%3563e-83Ecm25p OS=Sugiyamaella lignohabitans GN=ECM25 PE=4 SV=1
ECM25_YEAST27.42%3614e-26Protein ECM25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM25 PE=1 SV=2
A0A1D8PFN0_CANAL27.03%3702e-25Ecm25p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM25 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1359

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 623

Detailed signature matches

  1. Domain IPR001251
    CRAL-TRIO lipid binding domain
    1. PS50191 (CRAL_TRIO)
    2. SM00516 (sec14_4)
    3. cd00170 (SEC14)
    4. G3DSA:3.40.52...
    5. PF13716 (CRAL_TRIO_2)
    6. SSF52087 (CRAL/TRIO...)
  2. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  3. Domain IPR000198
    Rho GTPase-activating protein domain
    1. SM00324 (RhoGAP_3)
    2. PF00620 (RhoGAP)
    3. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.55...
  2. cd00159 (RhoGAP)
  3. mobidb-lite (disord...)

Residue annotation

  1. phospholipid bindi...
  2. salt bridge cd00170
  3. catalytic residue ...
  4. GTPase interaction...

Protein sequence

>MCA_03663_1
MSSSYPKDELDILAQRIVYSSKTFDPETRLPIVIMNSTSFPSSPEKYTPELMSKIISRLPNSSYVLVFFACGAPNKPSWS
WISKIYNMLDRQIKKRVGKVYIVHESWWVRAVMEMFRGIVSNKFKSKVVHVSSLSQLAKHIDITLINIPPDVYIHNIKNE
PVITIPRHHSPIFGVPLKKEGNRIIYPKMWPDCIQYLKVTAIFTKNIFQKEEDPELVTIVKQCYDRGQLLDLDDYGPHVT
ASLIKSYLHELPNPLLPIKYIPLPIQDTLEYNRQVFQSLPDITQKFITDLIPLFITIIENHSRTLQTPKTIALSISPSLI
GRYASSKESMAIAVRFTRNLIDFWPQISSSLHIDSSDDDDSDDDCFYKPESTTISNRKAFTRHLNGSLQDSIKDRTLKRV
NSDLSYSSVGSDGSSSYNKITSALNDELTQLHHFPNADARSLSSSNSSIYSGVEGRNINSNLAIAVAAPVDKKISDSTGR
LTSRSDESLVTPTTPIFASMSTPSIPSTKNMANSNNNSSNSSSNSSSARSSLAQPPPPPPPLRKSASTAFRTSFTSGELR
ERKSMSNLSDKRSCSLPIGPNGKPVTISTKRGKMVAELAKLYEEREEVGVLQEVKNQNIRQST

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.