Protein

MCA_03655_1

Length
584 amino acids

Gene name: VPS17

Description: Vacuolar protein sorting-associated protein 17

Browser: contigC:669876-671809+

RNA-seq: read pairs 5831, FPKM 123.2, percentile rank 82.2% (100% = highest expression)

Protein function

Annotation:VPS17Vacuolar protein sorting-associated protein 17
EGGNOG:0PGQ6VPS17Vacuolar protein sorting-associated protein
SGD closest match:S000005658VPS17Vacuolar protein sorting-associated protein 17
CGD closest match:CAL0000176868VPS17Vacuolar protein sorting-associated protein 17

Protein alignments

%idAln lengthE-value
MIA_03795_170.42%4800.0MIA_03795_1
A0A0J9XFY4_GEOCN70.13%4620.0Vacuolar protein sorting-associated protein 17 OS=Geotrichum candidum GN=BN980_GECA14s02089g PE=3 SV=1
UniRef50_A0A0J9XFY470.13%4620.0Vacuolar protein sorting-associated protein 17 n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XFY4_GEOCN
A0A167C8F1_9ASCO63.91%4600.0Vps17p OS=Sugiyamaella lignohabitans GN=VPS17 PE=4 SV=1
A0A060SXI1_BLAAD52.66%6020.0Vacuolar protein sorting-associated protein 17 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03828g PE=3 SV=1
A0A1E3PSL6_9ASCO47.63%5902e-161Vacuolar protein sorting-associated protein 17 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81390 PE=3 SV=1
A0A1E4TH68_9ASCO49.23%4578e-141Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_116463 PE=4 SV=1
VPS17_YEAST39.74%4582e-101Vacuolar protein sorting-associated protein 17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS17 PE=1 SV=2
Q6C8A4_YARLI41.67%4323e-94Vacuolar protein sorting-associated protein 17 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D21362g PE=3 SV=1
Q5A8Z0_CANAL38.21%4242e-87Vacuolar protein sorting-associated protein 17 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPS17 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0403

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 584

Detailed signature matches

  1. Family IPR014461
    Vacuolar protein sorting-associated protein 17, Vps17
    1. PIRSF011791 (Retrom...)
  2. Domain IPR001683
    Phox homologous domain
    1. PF00787 (PX)
    2. SM00312 (PX_2)
    3. G3DSA:3.30.15...
    4. SSF64268 (PX domain)
  3. Domain IPR015404
    Sorting nexin Vps5-like, C-terminal
    1. PF09325 (Vps5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.12...
  3. cd06891 (PX_Vps17p)
  4. mobidb-lite (disord...)

Residue annotation

  1. putative phosphoin...

Protein sequence

>MCA_03655_1
MASSVPYDPDGFDSPDVNPFAQEESLSSSQWKTEDVDKDEQNDNLQQSKADESTDAESHSKDKPTETEQSDATQNTTNTQ
SSKPSASQESSTQPQPTSTNTPVSNPAQQQQTTAPKPQKKKYKLLLKVTGLERQGKKDPIIKFDAFTTLPRFRTTTFRDI
RRTHHEFLKFGAHLSNANPECFVPSVPPAVSSAGAGTEEDEIKVKKRIQLWLDRVSSNPILARDEEFVHFIESDFGYSPV
NKRKPPATGVTRKALKQLQPPHDEVVELAQFRPVVKQLYITGQETVTKIERLSKARRSLGLALNDFGSKLYEFSDTETTG
NSNLVLMWRKLGKIVTGLGDLEAIKATTEAVTLTDGLNWVIKDAYVAKEAMTNRHLLMRDLAKAQAVTKSKHQTAVKLKG
STNIAPIKVDEALNSLKNAELVEEQLTNKVRLVTENMLMEKDILSKRIETDVKSYIAEYVVRIIDAERRALSAWESVRSD
VRAADANGGLSRLGREAHPPRRKATHISSQGAKGDAWSDRKVRAKDLGDPTALQQSSTAAGELTASVNSTATSNEDDDVQ
DIENGEATQVDARSAASLLSGLTF

GO term prediction

Biological Process

GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi

Molecular Function

GO:0035091 phosphatidylinositol binding

Cellular Component

GO:0030904 retromer complex