Protein

MCA_03651_1

Length
386 amino acids

Gene name: RRT12B

Description: subtilisin-like peptidase

Browser: contigC:660378-661682+

RNA-seq: read pairs 566, FPKM 18.1, percentile rank 38.7% (100% = highest expression)

Protein function

Annotation:RRT12Bsubtilisin-like peptidase
KEGG:K14644OSW3 subtilase-type proteinase RRT12 [EC:3.4.21.-]
EGGNOG:0PHPUPGUG_00804Subtilase family
SGD closest match:S000000641RRT12Subtilase-type proteinase RRT12
CGD closest match:CAL0000199679CAALFM_CR00660WAUncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_05112_174.65%3590.0MIA_05112_1
A0A0J9X3G9_GEOCN59.84%3862e-167Similar to Saccharomyces cerevisiae YCR045C RRT12 Probable subtilisin-family protease OS=Geotrichum candidum GN=BN980_GECA02s04129g PE=3 SV=1
UniRef50_A0A0J9X3G959.84%3865e-164Similar to Saccharomyces cerevisiae YCR045C RRT12 Probable subtilisin-family protease n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X3G9_GEOCN
A0A060T9X0_BLAAD56.83%3223e-127ARAD1D15004p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D15004g PE=3 SV=1
Q6CFX4_YARLI50.00%3624e-123YALI0B02794p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02794g PE=3 SV=2
A0A1D8PRS3_CANAL38.37%3446e-77Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR00660WA PE=3 SV=1
A0A1E4THQ1_9ASCO40.56%3602e-76Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_121669 PE=3 SV=1
RRT12_YEAST37.33%3753e-74Subtilase-type proteinase RRT12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRT12 PE=1 SV=1
A0A1E3PQF7_9ASCO37.05%2512e-45Subtilisin-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82078 PE=4 SV=1
A0A161HIN7_9ASCO58.59%1288e-46Rrt12p OS=Sugiyamaella lignohabitans GN=RRT12 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0854

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 386

Detailed signature matches

  1. Family IPR015500
    Peptidase S8, subtilisin-related
    1. PR00723 (SUBTILISIN)
  2. Domain IPR000209
    Peptidase S8/S53 domain
    1. PF00082 (Peptidase_S8)
    2. G3DSA:3.40.50...
    3. SSF52743 (Subtilisi...)
  3. Domain IPR034193
    Proteinase K-like catalytic domain
    1. cd04077 (Peptidases...)
  4. SITE IPR022398
    Peptidase S8, subtilisin, His-active site
    1. PS00137 (SUBTILASE_HIS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Residue annotation

  1. calcium binding si...
  2. catalytic triad cd...
  3. active site cd04077
  4. calcium binding si...

Protein sequence

>MCA_03651_1
MLQSLIGGVLFLLAGICHCTDHSQNESESVIIQFLPELNAERFLTVYPSLRHKVEGNITVGSFKAVYGKFDSRFVRLLTY
SNLVLDVSRDANVRISSVQSDSPRHLSRLSRIDGLSVIGPHDYVYDPSAGHGVDVYVFDTGIYREHPSFENRVTLGMDFT
GEGPGDGNGHGTFVAGIIGSKTHGVAKRANIIDIKVIGANGKGKLSRVLKGIDYVIRMKEQTNRPAVINMSFATMRNNVF
NRAIQAVMERDIPVVTAAGNQDTSACRMSPASVPNVLVVGAFDDRTDTIASFSNWGQCVDAFAPGVNVDSLEHQGNSFVQ
FSGTSVSSAIGSGLVAYFMGMGDLGLEAVDRVRDLRSKDKLSPQSFMFRPLTQNYILYNDAGEPLW

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.