Protein

MCA_03633_1

Length
208 amino acids


Gene name: HPT1

Description: Hypoxanthine phosphoribosyltransferase

Browser: contigC:600279-600906+

RNA-seq: read pairs 3845, FPKM 227.3, percentile rank 89.5% (100% = highest expression)

Protein function

Annotation:HPT1Hypoxanthine phosphoribosyltransferase
KEGG:K07101uncharacterized protein
EGGNOG:0PIW2HPT1phosphoribosyltransferase
SGD closest match:S000003894XPT1Xanthine phosphoribosyltransferase 1
CGD closest match:CAL0000179091HPT1Hypoxanthine phosphoribosyltransferase

Protein alignments

%idAln lengthE-value
MIA_05150_183.57%2076e-129MIA_05150_1
A0A0J9XBD9_GEOCN76.70%2065e-114Similar to Saccharomyces cerevisiae YJR133W XPT1 Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine OS=Geotrichum candidum GN=BN980_GECA08s04685g PE=4 SV=1
A0A167DGT2_9ASCO75.24%2069e-112Xanthine phosphoribosyltransferase OS=Sugiyamaella lignohabitans GN=XPT1 PE=4 SV=1
A0A060SYR4_BLAAD73.66%2058e-110ARAD1A13992p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A13992g PE=4 SV=1
Q6C5M6_YARLI72.68%2052e-107YALI0E16753p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16753g PE=4 SV=1
UniRef50_Q6C5M672.68%2056e-104YALI0E16753p n=10 Tax=saccharomyceta TaxID=716545 RepID=Q6C5M6_YARLI
A0A1E3PHB3_9ASCO71.84%2066e-106PRTase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47343 PE=4 SV=1
A0A1E4TBT0_9ASCO71.92%2032e-104Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_134474 PE=4 SV=1
XPT1_YEAST64.08%2066e-92Xanthine phosphoribosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=XPT1 PE=1 SV=1
A0A1D8PGN7_CANAL60.98%2053e-76Hypoxanthine phosphoribosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HPT1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0270

Protein family membership

None predicted.

Domains and repeats

1 20 40 60 80 100 120 140 160 180 208

Detailed signature matches

    1. SSF53271 (PRTase-like)
    1. cd06223 (PRTases_typeI)
    2. PF00156 (Pribosyltran)
Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. active site cd06223

Protein sequence

>MCA_03633_1
MSIEKKYISYNHVHKLCQEAAGIIKTKFRPDLMIAIGGGGFIPARILRTFLKEPGQKNIPIQAIGLSLYEDLGVEDEYAE
SLGTQVIRTQWLDFGTMAQRSVEFIGKTVLIVDEVDDTRTTLHYALSELEKDVAAQAQKLGRQDEKTTFLIFVLHNKDKQ
KKAQLPNEMVEEGRYIAARTVPDVWIAYPWEARDIETHTKNAIEQGNN

GO term prediction

Biological Process

GO:0009116 nucleoside metabolic process

Molecular Function

None predicted.

Cellular Component

None predicted.