Protein

MCA_03606_1

Length
2,738 amino acids

Gene name: GCN1

Description: eIF-2-alpha kinase activator GCN1

Browser: contigC:514376-522665-

RNA-seq: read pairs 4566, FPKM 20.6, percentile rank 42.2% (100% = highest expression)

Protein function

Annotation:GCN1eIF-2-alpha kinase activator GCN1
EGGNOG:0PHJYGCN1Translational activator GCN1
SGD closest match:S000003163GCN1eIF-2-alpha kinase activator GCN1
CGD closest match:CAL0000192579GCN1Gcn1p

Protein alignments

%idAln lengthE-value
MIA_05174_162.52%27430.0MIA_05174_1
A0A0J9X7M8_GEOCN55.33%27490.0Similar to Saccharomyces cerevisiae YGL195W GCN1 Positive regulator of the Gcn2p kinase activity OS=Geotrichum candidum GN=BN980_GECA04s04839g PE=4 SV=1
UniRef50_A0A0J9X7M855.33%27490.0Similar to Saccharomyces cerevisiae YGL195W GCN1 Positive regulator of the Gcn2p kinase activity n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X7M8_GEOCN
A0A060T9P0_BLAAD46.54%27480.0ARAD1B00704p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B00704g PE=4 SV=1
A0A167FV98_9ASCO47.19%26320.0Gcn1p OS=Sugiyamaella lignohabitans GN=GCN1 PE=4 SV=1
A0A1E3PFL9_9ASCO44.44%27630.0ARM repeat-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83757 PE=4 SV=1
GCN1_YEAST39.95%27810.0eIF-2-alpha kinase activator GCN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCN1 PE=1 SV=1
A0A1D8PIR2_CANAL40.02%26360.0Gcn1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GCN1 PE=4 SV=1
Q6C8Q9_YARLI40.70%23710.0YALI0D17732p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17732g PE=4 SV=1
A0A1E4TG74_9ASCO36.39%25940.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_51022 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0580

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Repeat
1 500 1000 1500 2000 2738

Detailed signature matches

  1. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  2. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  3. Domain IPR022716
    Gcn1, N-terminal
    1. PF12074 (Gcn1_N)
  4. Domain IPR034085
    TOG domain
    1. SM01349 (TOG_3)
  5. Repeat IPR021133
    HEAT, type 2
    1. PS50077 (HEAT_REPEAT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_03606_1
MSEQSTDSWAFLKPIANTQLLLSSPISRTAFMKKLFNLTRVENTSDNDLKEVLSVVFLKYPHYNDHESRRSAQEIIIKFI
ETSENLSLLSSFSLLVQNVANNKSSQSVSSLLNVLEWCNKVLIQFAPVYSSHQDSLKTLIIAQAKLVYKIVTIPTIEKRS
RQYNSTVSSLRSTIAKSLTRSDFDSSPEFAQFFLETLIEKPNTPTDYVFRLISVAALAGAAIDVLPVKPGVQVKVEEKKD
EIFTIYNQAILGTKVALPLTLVDTYSPLFIDFTSQSDFDNKIAPAVAKAFLRSPEIIMSTISITLFQKLSPLVDTADSLN
SCLLSPLLSAFSSSKPNVRVYASQNLQALLALAQPTEKLSKVLTSIVTPLKTNKVTSHEQRFFYGEVLKSLNPYLEGSPI
IYNNILTTVGKEVNEQSLIVLTEAFFKHLIFDLQSNAIIDKKVTEAVVKGMTDKKANLKRVWVTSFVGEIFNQPNSCSAE
LESFINSLSKPLIDSWKEVNTNPPGSILNKSTAIGFAVVALTSKLELLNPDLLKPYKEADVINNSLKNDKHSFLISHKTF
TKLTEPTDVEWAIRALKASAANVVDIDDGEIANDWALTWIYYITSPVSSTTSRLAISLLKDTYVSFQSFVGSLFISNIQQ
LLLDPTSKNDNNLSYIPKTKFNSIILALFRSNDKIDSSIFESNLVSLFVISHHPDVPIKGGWVTLCLESDMDPGAIVSAH
SDRLLNSCFEMAELASNIGNEVMLEASLAAVTTLSFINPSLFVSRITSTIKEGLNTNDFTTELEPELVKKIWETPEGELA
IDPFASKKTYVENKNTKDYETKKWEESVRKEIASKKGIKDNKPKYTKEQQATVNEQLKKETEIRSQLRSIYHRVHKLLVL
ITKLSDMAVTAYNGIEDWYPVSCKLLLDMLTTGKVNFIFKGEASRTFIKLSQNVASKLLLNLRDISGVAILRGLNATEVD
SLALTTKEALKESVLSILYRIKFYSEKGKIDVISLIYLTPLLLRVLEGKGGIAASTEDESEEQTILALDIITDQADMFKE
EVTSRMHLLTTLLGFLEAHPSKAKRIKDVLNRIVQSIGDSFNDDELQLFLKLTISSDPAIRTIILEIIDNELDISHLKYS
SEIFIELFDENPTNAELAESIWTDNELEVDSSTPFKLLPFLESEDDSVRASAAQAIASAASRFPDLVPSVFNDLVDYFKE
KSKPPVPVKDKYGVPVNLGDESDTWKPREGAAKAFSHLAPYLTNELIEKFFKFLIQEDGLGDANSHVREQIQEAGKTIIQ
AHGIKIVEILIPIFEDYLSKDIKKPTEVQDRIRESVVILYGALARHLKPSDPRAEKIVERLISTLDTPNEYVQYAVSECL
ADLVFLFSSKIGDYLQKLQDKLFNDSKYAHRRGAAYGISGIVKGCGIVALADYDIIRILIDAVEDKKDPKKRQGAQFAFE
TLSQSLGQYFEPYVFEIIPLILASLGDSSADVREATSFAAKQIMKHATGYGIKKLIPLTLESLDQTAWRAKKGAVELLGI
MAYLDPRQLSTSLSVIIPELVGVLNDTHREVRSSANQSLQKFGEVIKNPEIQSLVPTLIKAISDPTKHTEEALDGLLKTQ
FIHYIDAPSLALVIHILHRGLKDRSANIKRKAAQIVGNMSILTDGKDLVPYLPDLVAELEISMVDPVPATRSTASRALGA
LVEKLGEDQFPDLIGRLMATLKSEDKVGDRLGSAQGLAEIVYGLGIRKLEELLPVILKNATSPKAHIREGFMPLMIFLPA
SFGASFTPYLSQIIPPILAGLSDDQSSIRETSLKAGRLLVKNYASKAVDLLLPELERGLSDYSHRIRAASVELTGDLLFQ
LTGVSGNTELAEEDKIIYGDVTKNIVEALGTERRDRIFAAIFICRSDIYPQVRGVAVEVWKSLVFNTPRTIKEILPTLTQ
TIIRRLASTNQDQRNIAAQALGELVRRVGGTSLSRLLPTLSEGMATSDPDARQGICIAVNELIGSTQPDDLEAQQGLIIP
IIRSGLGDSDERVCDSAANAFDSLQNAIGNQIMDKILPDLINMLQNESTADNALAALKKIISTKGAIVFPVLMPTLLKPP
MTVTNARSLGALASVAGPALIKRFEKIVDSLIDAIVGEDGEEPSEQDAETFKESLNSVLLSINFDEGVHTLMHHMLSLAR
NPEPKRREITFEHMSEYFSETSVDYSNYIEDWVGVCITSLDDVDPNVVKAAWQCLNSIIKAQSKEQLAALVRTARSTLRS
TGTPGQELPGFALPKGASCILPIFLQGLMYGTNDQREQAALGISDVVERTSAANLKPFVTQITGPLIRTVGERFPSPIKA
AIMYTLNTLLVKIPAFLKPFLPQLQRTFAKALADPTNETLRSRAGKALSTLVKLQPKVDPLVTELVTSANSTNDEAVVES
ILQSLSDIVIVAGSKLGPTSKSLISNFVEDELLKSGSHRRITLAKLVGGITNAMDGEEAKKYITSSVLNNSSNQQFAVLT
LNTLLKVAGPKIDEAGVSKDIANYLIAHINDADDEISENSIRAAGKYLLATTATEEVAIDEELKNSSSPFTLEFRNIKLN
FDHSPEIVLGLVKELAEAMVKSPSKSVETRRLALVVVRTLARHKYDMVCQYECLDILVPAIFGCVRDSVIPVKLAAEKAY
LQIFKLTQELEENPEDKSKQQETFEKWFKHATEANVLPGTLGRSVSEYTKRVATRLASAEVERIAAGGDYTAVFSDRMED
EEDLWAIGSVELSIEEDI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding

Cellular Component

None predicted.